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  • Digitale Medien  (4)
  • 2D binary shape description  (1)
  • Carcinogenesis  (1)
  • MAS  (1)
  • Mesonephros  (1)
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  • Digitale Medien  (4)
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  • 1
    Digitale Medien
    Digitale Medien
    The carcinogenic effect of 2,2-dioxopropylnitrosamine on the renal pelvic epithelium of Sprague-Dawley rats, after chronic subcutaneous injections (1992)
    Springer
    Journal of cancer research and clinical oncology 118 (1992), S. 222-227 
    Details
    ISSN: 1432-1335
    Schlagwort(e): Renal pelvis ; Carcinogenesis ; 2,2-Dioxopropylnitrosamine ; Rat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The carcinogenicity of 2,2-dioxopropylnitrosamine on the urinary tract was investigated in three experimental groups of Sprague-Dawley rats (15 males, 15 females/group) by weekly subcutaneous administration for the life of the carcinogen at dose levels 1/5, 1/10 and 1/20 of the LD50, and compared with that in a similar group of untreated controls. It resulted in the induction of urinary tract tumours in 42 out of 79 effective animals (53%). Of these animals, 38 developed tumours within the renal pelvis. In the high-dose group, females had a 100% incidence of renal pelvic tumours, and males 73%. In all experimental groups, renal pelvic tumours were more frequent than ureteral and vesical ones. Histologically, the tumours were transitional cell papillomas and carcinomas, except for one squamous carcinoma. Out of 66 tumours, 42 (64%) were low-grade. High-grade tumours arose mainly in the renal pelvis of animals belonging to the highest-dose group. This experiment offers a useful model for the study of mechanisms involved in renal pelvic carcinogenesis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01410138
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  • 2
    Digitale Medien
    Digitale Medien
    Pyramiding of bacterial blight resistance genes in rice: marker-assisted selection using RFLP and PCR (1997)
    Springer
    Theoretical and applied genetics 95 (1997), S. 313-320 
    Details
    ISSN: 1432-2242
    Schlagwort(e): Key words Rice ; Bacterial blight ; Resistance genes ; Pyramiding ; MAS
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract  DNA marker-assisted selection was used to pyramid four bacterial blight resistance genes, Xa-4, xa-5, xa-13 and Xa-21. Breeding lines with two, three and four resistance genes were developed and tested for resistance to the bacterial blight pathogen (Xanthomonas oryzae pv. oryzae). The pyramid lines showed a wider spectrum and a higher level of resistance than lines with only a single gene. To speed up the gene pyramiding process and to facilitate future marker-aided selection, we developed PCR markers for the two recessive genes, xa-5 and xa-13, and used these to survey a range of rice germplasm. The results of the germplasm survey will be useful for the selection of parents in breeding programs aimed at transferring these bacterial blight resistance genes from one varietal background to another.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s001220050565
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  • 3
    Digitale Medien
    Digitale Medien
    Immunohistochemical localization of transforming growth factor-α and epidermal growth factor-receptor in the mesonephros and metanephros of the chicken (1993)
    Springer
    Cell & tissue research 271 (1993), S. 3-8 
    Details
    ISSN: 1432-0878
    Schlagwort(e): Transforming growth factor-alpha ; Epidermal growth factor-receptor ; Mesonephros ; Metanephros ; Domestic fowl
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary Transforming growth factor-alpha (TGF-α) is a polypeptide related to epidermal growth factor (EGF). Both bind to EGF-receptor (EGF-R) to carry out their function in a variety of tissues and cell lines. Several studies have shown their presence in mammalian kidney, however, nothing has to date been stated concerning their existence in avian kidney. Expression of TGF-α and EGF-R is reported here for the first time during the development of the chicken kidney. Using immunohistochemical techniques, we identified a TGF-α (but not EGF) in mesonephric distal tubule cells from day 8 to day 20 of embryonic development and in metanephric distal tubule cells from day 14 of embryonic development to the adult. The histochemical characteristics of these cells and their histological localization suggest that they may be the “principal cells” of the distal tubules. Similarly, EGF-R was found in mesonephric proximal tubule cells from day 7 to day 18 of embryonic development and in metanephric proximal tubule cells from day 13 of embryonic development up to adult stages. The coexistence of both TGF-α and EGF-R from the onset of development of mesonephros and metanephros supports their possible role in mechanisms of proliferation and differentiation of the cells of these organs.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00297536
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  • 4
    Digitale Medien
    Digitale Medien
    Robust Descriptors of Binary Shapes with Applications (1999)
    Springer
    International journal of computer vision 34 (1999), S. 5-17 
    Details
    ISSN: 1573-1405
    Schlagwort(e): 2D binary shape description ; stochastic mathematical morphology ; granulometry ; geometric covariogram ; shape matching
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Informatik
    Notizen: Abstract The subject of this paper is to propose and test a set of numerical descriptors of 2D binary planar shapes. Given a shape, A, the transformations of A with a given mathematical morphological operation and different structuring elements are considered. The measures of this family of transformed sets provide a numerical description of the original set A. These descriptors are very robust against noise and maintain a reasonable discriminatory power. The robustness against different levels of contour degradation is tested by simulation. Starting with a clean (without noise) set, Λ, it is assumed that the observed set, A, is a noisy version (with contour degradation) of Λ. The performance of the descriptors, when they are used to compare different shapes or shapes from a scene with models, is studied and compared with related descriptors based on the granulometric analysis of the original set, which are the closest previous alternative to our approach in the literature.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1008164518969
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