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  • Electronic Resource  (4)
  • Corrosion casting  (3)
  • Blutgefäße  (1)
  • 1
    ISSN: 1432-2307
    Keywords: Key words Bladder cancer ; Blood vessels ; Angiogenesis ; Corrosion casting
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The vascular architecture of five advanced invasive papillary tumours of the urinary bladder was investigated using corrosion casting and scanning electron microscopy. The superficial vasculature was composed predominantly of capillary systems of two types: dense flat networks with numerous interconnections and tightly packed tortuous loops, forming multiple irregular folds that reflected the papillary morphology of the tumours. The capillaries were supplied and drained by numerous straight nonanastomosing arterioles and venules, which arose by way of multiple branching of larger vessels originating from the mucosal plexus of the bladder. Differences between the tumours in the spatial arrangement of these vessels probably reflect different growth dynamics. The intramural parts of the tumours contained a chaotic network of straight, uniform capillaries with numerous sprouts, which was very different from the superficial capillary system. It is postulated that different angiogenesis-targeted growth factors may be expressed in the phases of exophytic growth and muscularis invasion of the tumour, leading to the formation of different microvascular patterns.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0568
    Keywords: Cartilage canals ; Blood vessels ; Development ; Human fetus ; Corrosion casting
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Formation of intrachondral vessels (cartilage canals) in the proximal femoral epiphysis was studied in 13- to 22-week-old human fetuses using a corrosion casting technique and scanning electron microscopy. Several successive morphological stages of angiogenesis occurring inside the hyaline cartilage were distinguished. The process of cartilage vascularization starts with the formation of hairpin loops sent off from the perichondrial vascular network into the adjacent cartilage. A capillary glomerulus is then formed at the leading end, and the entire vascular unit grows in length, assuming a mushroom-like shape. Its further elongation is accompanied by a backward expansion of the capillary network which surrounds a pair of main vessels (arteriole and venule) like a manchette. The subsequent branching of such primary vascular units proceeds according to the same morphological patterns. The resulting tree-like vascular formations become interconnected via their lateral branches. This study clearly supports the invasion theory of cartilage canal formation.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 100 (1981), S. 271-283 
    ISSN: 1432-1335
    Keywords: Cancer of the larynx ; Blood vessels ; Microcorrosion casts ; SEM ; Kehlkopfkarzinom ; Blutgefäße ; Plastik-Korrosion-Präparate ; Rasterelektronenmikroskopie (REM)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Mit Hilfe der REM wurde die Morphologie der Innenabdrucke von Blutgefäßen bei Kehlkopfkarzinom untersucht. Als bösartige Geschwulst produziert es TAF und ist somit fähig, den Prozeß der Neoangiogenesis in Gang zu setzen. Die größten Unterschiede in den Replika-Mustern des Endothels im Vergleich mit denjenigen von normalem Gewebe wurden bei Kapillaren, Venolen und Venen festgestellt. In allen Zonen des Kehlkopfkarzinoms machen Kapillargefäße den größten Anteil des Blutgefäßlagers aus. Auch erweisen sie die stärkste morphologische Differenzierung sowohl im Fall von blind endenden, kolbenförmig im distalen Abschnitt erweiterten Röhrchen als auch bei Schlingen, die durch Gefäße recht verschiedenen Durchmessers gebildet werden, und deren Arme während ihres Wachstums einer oft sehr starken Verwindung und zusätzlichen Biegungen unterliegen. Die sich neu bildenden Kapillargefäße, die vor allem dem veno-kapillaren Gefäßlager der Umgebung entstammen, entsprechen dem Typ embryonaler Blutgefäße. Deshalb ist es sehr wahrscheinlich, daß der durch aktives Einwirken von TAF hervorgerufene Prozeß der Neoangiogenese im Prinzip einer Repetition der Mechanismen der embryonalen Angiogenese gleichkommt.
    Notes: Summary Morphology of blood vessels in cancer of the larynx, which as other solid tumors has great neoangiogenic abilities, was studied on microcorrosion casts in SEM. Most evident changes of the endothelial patterns were seen on the casts of capillaries, venules, and veins. Capillaries, especially the newly formed, are the most numerous constituent of the vasacular bed in all zones of cancer of the larynx. These vessels exhibit great morphological differentiation varying from the single, blind-ended pipes via relatively long hairpin loops spirally twisted in the long axis, to strongly spiralled and convoluted loops, resembling pseudoglomeruli. The newly formed capillaries deriving predominantly from the host's capillaries, venules, and veins have an embryonal character. It seems resonable to presume that the neoangiogenesis process triggered by active influence of the tumor angiogenesis factor, is in principle, a repetition of the mechanism of the embryonal angiogenesis.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 242 (1995), S. 411-416 
    ISSN: 0003-276X
    Keywords: Blood vessles ; Nasal mucosa ; Human fetus ; Corrosion casting ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Background: The vasculature of the nasal mucosa in the human fetus so far has not been investigated morphologically by modern techniques.Methods: Nasal blood vessels were studies in 18-21-week-old human fetuses by corrosion casting and scanning electron microscopy.Results: The general vascular architecture was similar to that described for adult humans, with (1) a dense network of subepithelial capillaries, (2) a mucosal layer of larger vessles, predominantly veins, and (3) large arteries located near the perichondrium. Specific vessel types characteristic of the nasal mucosa and important for its functions in adults, such as cavernous veins or cushion veins, were, however, absent in the fetuses, although probable precursor forms of cushion veins could be observed. The arteriovenous anastomoses had the form of short bridges, and no tortuous or glomerular anastomoses present in the mature nasal mucosa were found.Conclusions: The underdevelopment of some vascular areas is postulated to reflect the functional immaturily of the respiratory system in the fetus. © 1995 Wiley-Liss, Inc.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
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