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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 39 (1984), S. 0 
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The lymphocyte subpopulations were classified using monoclonal antibodies specific for B lymphocytes (B1 antibodies), T lymphocytes (T11 and OKT3 antibodies). Helper/inducer T cells (T4 antibodies) and suppressor/cytotoxic T cells (T8 antibodies). Three groups of subjects were studied: 20 normal controls, 29 patients with allergic rhinitis and a subgroup of nine patients who had received immunotherapy. The proportion of B Lymphocytes, total T cells and T4 positive (helper/inducer) cells were not significantly different between the groups, but allergic patients were found to have a decreased proportion of suppressor T8 positive (suppressor/cytotoxic) cells and hence a high helper/suppressor cell ratio. These received immunotherapy. These results imply that a suppressor cell deficiency may be an underlying mechanism of allergic disease, and that immunotherapy could correct the suppressor cell deficiency.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 20 (1990), S. 0 
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Peripheral blood mononuclear cell (MNC) response to house dust (HD) stimulation in cultures was studied in a group of 35 subjects with asthma and a multiple positive skin test (ST) reaction to inhalant allergens including HD, and in 19 healthy controls. The MNC response to allergen stimulation was assessed by interleukin-2 receptor (IL-2R) expression identified with an anti-Tac monoclonal antibody. Lymphocyte subpopulations of baseline and cultured cells were also analysed. The percentage of IL-2R presenting cells increased significantly in HD-driven cultures in the asthma group compared to controls. The increase in proportion of IL-2R+ cells was closely related to the increase in CD4+ percentage of cultured cells and was accompanied by a decrease in proportion of CD8+ lymphocytes and monocytes/macrophages, suggesting that HD-activated cells were CD4+ lymphocytes. Lymphocyte activation, measured by IL-2R expression, was significantly higher in the group of asthmatics, and positive dual (early and late) skin reaction to HD, as compared to those with single early reaction.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 100 (1981), S. 271-283 
    ISSN: 1432-1335
    Keywords: Cancer of the larynx ; Blood vessels ; Microcorrosion casts ; SEM ; Kehlkopfkarzinom ; Blutgefäße ; Plastik-Korrosion-Präparate ; Rasterelektronenmikroskopie (REM)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Mit Hilfe der REM wurde die Morphologie der Innenabdrucke von Blutgefäßen bei Kehlkopfkarzinom untersucht. Als bösartige Geschwulst produziert es TAF und ist somit fähig, den Prozeß der Neoangiogenesis in Gang zu setzen. Die größten Unterschiede in den Replika-Mustern des Endothels im Vergleich mit denjenigen von normalem Gewebe wurden bei Kapillaren, Venolen und Venen festgestellt. In allen Zonen des Kehlkopfkarzinoms machen Kapillargefäße den größten Anteil des Blutgefäßlagers aus. Auch erweisen sie die stärkste morphologische Differenzierung sowohl im Fall von blind endenden, kolbenförmig im distalen Abschnitt erweiterten Röhrchen als auch bei Schlingen, die durch Gefäße recht verschiedenen Durchmessers gebildet werden, und deren Arme während ihres Wachstums einer oft sehr starken Verwindung und zusätzlichen Biegungen unterliegen. Die sich neu bildenden Kapillargefäße, die vor allem dem veno-kapillaren Gefäßlager der Umgebung entstammen, entsprechen dem Typ embryonaler Blutgefäße. Deshalb ist es sehr wahrscheinlich, daß der durch aktives Einwirken von TAF hervorgerufene Prozeß der Neoangiogenese im Prinzip einer Repetition der Mechanismen der embryonalen Angiogenese gleichkommt.
    Notes: Summary Morphology of blood vessels in cancer of the larynx, which as other solid tumors has great neoangiogenic abilities, was studied on microcorrosion casts in SEM. Most evident changes of the endothelial patterns were seen on the casts of capillaries, venules, and veins. Capillaries, especially the newly formed, are the most numerous constituent of the vasacular bed in all zones of cancer of the larynx. These vessels exhibit great morphological differentiation varying from the single, blind-ended pipes via relatively long hairpin loops spirally twisted in the long axis, to strongly spiralled and convoluted loops, resembling pseudoglomeruli. The newly formed capillaries deriving predominantly from the host's capillaries, venules, and veins have an embryonal character. It seems resonable to presume that the neoangiogenesis process triggered by active influence of the tumor angiogenesis factor, is in principle, a repetition of the mechanism of the embryonal angiogenesis.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Environmental monitoring and assessment 61 (2000), S. 133-144 
    ISSN: 1573-2959
    Keywords: adaptation scenarios ; climate change ; agriculture ; Poland
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract This paper demonstrates the ability of Polish agriculture to adapt to predicted climate change according to GISS and GFDL scenarios. Both climate-change scenarios will significantly affect farming conditions in Poland through water deficit, shifts in planting and harvesting seasons, changes in crop yields and crop structure. Neither scenario seems to endanger the self-sufficiency of Poland as long as preventative measures are taken. Moreover, the realization of GISS creates the possibility of a surplus in production. It must be emphasized that regardless of the scenario, the adaptation of agriculture to an expected climate change cannot be handled by the farming community itself.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The mechanical properties of poly(urethaneimides) (PUI) were compared with known biomedical polyurethanes. The resistance of PUI to extraction with hexane and water and to sterilization with ethylene oxide or water vapor was stated. Water sorption and the permeability of water vapor, oxygen, and carbon dioxide through PUI foils were investigated. In blood compatibility, the PUI foils were similar to cellulose material Cuprophane, used in dialysis. Preliminary in vivo testing of PUI implanted in rats indicated good biocompatibility of this polymer. © 1995 John Wiley & Sons, Inc.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
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