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  • Electronic Resource  (2)
  • Marchiafava-Bignami disease  (1)
  • traditional angiography  (1)
  • 1
    ISSN: 0942-0940
    Keywords: Echotomography ; traditional angiography ; atherosclerosis ; carotid lesions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sixty-three patients (115 carotid arteries) have been examined first by Dopplersonography, then by echotomography and finally by angiography using the Seldinger technique. The comparison between echotomography and angiography showed a sensitivity of 0.9, a specificity of 0.7 and a accuracy of 0.8. There have been 15 false positive results; in 14 of them the lesions were lower than 10% of lumen reduction and in one case there was a 10–45% stenosis. It seems that echotomography can better estimate lower degree lesions. It was difficult for echotomography to detect correctly the presence of an occlusion and to evaluate the surface aspect mainly in the presence of ulcerations.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1435-1463
    Keywords: Marchiafava-Bignami disease ; corpus callosum ; brain glucose utilization ; Positron Emission Tomography ; alcoholism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The Cerebral Metabolic Rate of Glucose (CMRGlu) was measured with positron emission tomography and18F-FDG in a patient with Marchiafava-Bignami Disease (MBD)-related dementia. Despite MRI evidence of lesions essentially limited to the corpus callosum (CC), but consistent with the cognitive pattern of cortical dementia, the CMRGlu was markedly reduced in the frontal and temporo-parieto-occipital association cortices. Disruption of cortico-cortical networks crossing the CC presumably contributed to, but may not in and by itself explain, the severity of the clinicalmetabolic findings in this patient. An additional role could be played by microscopic white matter lesions and/or neocortical neuronal loss, which have been occasionnally observed in post-mortem studies of MBD patients.
    Type of Medium: Electronic Resource
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