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  • Electronic Resource  (2)
  • Radionuclide ventriculography  (2)
  • 1
    ISSN: 1619-7089
    Keywords: Radionuclide ventriculography ; Aneurysm ; Ejection fraction ; Underestimation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The left-ventricular ejection fraction (LVEF) of 72 patients with aneurysm of the anterior wall was measured by multiple gated blood pool acquisition (MUGA) in the anterior and left anterior oblique (LAO) positions, and by cineangiography (CA) in right anterior oblique (RAO) and LAO projections of 30° and 60°, respectively. The LVEF was overestimated by CA in the LAO projection and by MUGA in the anterior position, but underestimated by CA in the RAO projection (6.1 percentage points) and by MUGA in the LAO position (6.2 percentage points). In 50 patients without aneurysm, no systematical error occurred using MUGA. The underestimation of the LVEF in patients with aneurysm by MUGA in the LAO position is due to differences of photon attenuation in various parts of the cardiac blood pool. This systematical error can be overcome by biplane MUGA.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1619-7089
    Keywords: Radionuclide ventriculography ; Aortic regurgitation ; Mitral regurgitation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In order to evaluate the significance of gated equilibrium radionuclide ventriculography (RNV) for non invasive quantification of valvular regurgitation and follow up, various approaches were tested concerning accuracy and reproducibility. By using in vitro labeling of red blood cells and extending the acquisition time, a clear reduction of dispersion was obtained in patients without valvular insufficiency. Quantification of regurgitation directly from functional images (ventricular amplitude or stroke volume image) was clearly superior compared to the variable region of interest method. Employing functional images, reproducibility between two observers and between two independent measurements was excellent. Correlation to regurgitation values determined by cardiac catheterization was only moderate with all RNV approaches tested. RNV is limited in the absolute quantification of valvular regurgitation due to the variable overlap of right atrium and right ventricle. However, because of its high reproducibility, RNV is a non invasive technique suitable for intraindividual follow up of patients with valvular insufficiency.
    Type of Medium: Electronic Resource
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