ISSN:
1573-4919
Schlagwort(e):
DNA topoisomerase I
;
camptothecin
;
αA-globin gene
;
c-Ha-ras gene
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Chemie und Pharmazie
,
Medizin
Notizen:
Summary Two molecular forms of topoisomerase I differing in size and sensitivity to camptothecin were isolated from calf thymus. Mapping of topo I cleavage sites of the cloned chicken αA-globin and human c-Ha-ras genes was carried out. Camptothecin was shown to affect site specificity of the topoisomerases.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00229529
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