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  • 11
    ISSN: 1434-601X
    Keywords: 25.70.Np
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Subthreshold ¯p andK − and energeticπ − production was studied in Ne + NaF, Cu, Sn and Bi, and in Ni + Ni collisions with incident energies between 1.6 and 2 GeV/u. The measured cross sections indicate a dominant contribution of baryonic resonances. This is also consistent with a generalized scaling behaviour of the cross sections with the energy available in the collision and the energy necessary to produce particles as observed with Ne induced reactions. Deviations from scaling especially pronounced in the Ni-Ni system will be discussed in terms of absorption effects. The flat slope of the excitation function for ¯p production can be related to a reduced production threshold caused by a reduction of the antiproton mass in the dense and heated medium by about 100—150 MeV/c2. A similar in-medium mass reduction is also indicated forK − mesons. An increased ¯p reabsorption probability for the heavier systems is concluded from the comparison of the ¯p yields in Ne + NaF, Ne + Sn and Ni + Ni collisions.
    Type of Medium: Electronic Resource
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  • 12
    ISSN: 1432-1440
    Keywords: Sarcoidosis ; Immune response ; Activity markers ; Soluble CD 14 ; Serum neopterin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary CD14 represents the most specific marker for monocytes/macrophages. It has been demonstrated in vitro that monocytes/macrophages lose this antigen upon activation. Results of studies investigating the expression of membrane-bound CD14 on the surface of monocytes/macrophages in sarcoidosis patients are controversial. To investigate whether the soluble form of CD14 reflects monocyte/macrophage activation in sarcoidosis, serum levels of soluble CD14 were determined concurrently with other serum markers of monocyte/macrophage activation (neopterin, angiotensin-converting enzyme) in 50 consecutive patients with bioptically confirmed sarcoidosis. The patients were allocated to three groups according to disease activity and therapy. The soluble interleukin-2 receptor in serum and the CD4/CD8 ratio in lavage fluid were used to monitor T-lymphocyte activation. No significant differences in serum or bronchoalveolar lavage levels of soluble CD14 were observed in patients with active or inactive sarcoidosis. Despite the presence of normal soluble CD14 serum concentrations a correlation with serum neopterin and angiotensin-converting enzyme was found in active sarcoidosis (soluble CD14 versus neopterin, r s = 0.61 and 0.65, P〈 0.05 and 0.01, respectively; soluble CD14 versus angiotensin-converting enzyme, rs=0.6 and 0.72, P〈 0.02 and 0.003, respectively). A correlation between soluble CD14 and parameters of T-cell activity was not demonstrated. We therefore conclude that soluble CD14 in serum is not a useful clinical parameter in establishing disease activity in sarcoidosis. Neopterin and angiotensin-converting enzyme serum concentrations are parameters with higher sensitivity, although specificity remains very low. The exact role of CD14 antigen in sarcoidosis requires further investigation.
    Type of Medium: Electronic Resource
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  • 13
    ISSN: 1434-601X
    Keywords: 23.60. +e ; 23.90. +w ; 27.60. +j
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract In fusion reactions of58Ni beams with54Pe and58Ni target nuclei neutron deficient evaporation residues have been produced and separated from the beam in an electrostatic deflector with large acceptance. The recoil nuclei were implanted and detected in an array of 100 PIN photodiodes, where also their particle decays were recorded. The assignment of the 0.81 MeV proton line to the decay of109I could be experimentally proven by the observation, that it is followed by the 3.31 MeV alpha emission from108Te. A proton decay from112Cs was not observed. The decay energies of a number of known α emitters have been measured with better precision.
    Type of Medium: Electronic Resource
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  • 14
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Blood specimens were collected from 15000 pregnant women during the first 3 months of their pregnancy and screened for amino acid disturbances by means of paper chromatography. A high incidence of disturbances in the phenylalanine metabolism was discovered: three cases of mild hyperphenylalaninaemia without phenylpyruvicaciduria (incidence 1:5000); two cases of mild hyperphenylalaninaemia with phenylpyruvicaciduria (incidence 1:7550); four cases of mild phenylketonuria (incidence 1:3750). Disturbances in the metabolism of other amino acids were found to be rare. Metabolic and genealogical findings in some detected families are briefly described.
    Type of Medium: Electronic Resource
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