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  • 1970-1974  (62)
  • 1972  (62)
  • Life and Medical Sciences  (50)
  • Ultrastructure  (12)
  • 1
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: One hundred and twenty-two larvae of Xenopus laevis, the South African clawed toad, at developmental stages 48, 50, 52 and 54, were implanted in the tail with two allografts from adult tissues. In each case, one allograft was from kidney, while the other was either from kidney, thymus, spleen, or liver. In any particular host the two implants were always from the same donor and the implants were all visually matched in size. The experimental period was a maximum of nine days, so as to minimize the large numbers of changes normally accompanying larval progress from stage to stage. We are concerned with the timing of allograft response initiation under the implant conditions of each experimental group at a particular point in development. An allograft response was defined as an infiltration and accumulation of small lymphocytes in the “test” kidney allograft. Larvae of all stages developed allograft responses within one week post-implantation when the variable implant was from kidney, but implants from spleen and thymus suppressed both the timing of initiation and the subsequent intensity of the response. Spleen was more effective in this regard than thymus and both were more effective in the earlier larval stages. Liver proved to be toxic to the larvae. The relationship between the maturation of the lymphomyeloid tissues and external morphological staging is also discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 137 (1972), S. 289-333 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The trabeculae cranii are at first quite separate from each other, after few days their anterior two fifths are connected by a trabecular plate which is obliterated throughout development. The paired origin of the parachordal plate is not observed. The fused posterior orbital cartilages chondrify in the form of a wide short plate, traversed by the oculomotor and trochlear nerves. The basicranial fenestra and fenestra ovalis are formed by the degeneration of pre-existing cartilage. The cochlear portion is completely fused with the parachordal plate from the very beginning. The elements of the pterygoquadrate are fused together. The quadrate and Meckel's cartilage are in close contact from the very beginning. While the lower part of the interorbital septum is derived from the trabecula communis, its upper part is derived from the anterior orbital cartilages. The lateral parts of the fused posterior orbital cartilages give rise to most of the taeniae and pilae of the orbitotemporal region. There is only one commissure between the auditory capsule and parachordal plate. A cartilaginous connection between the distal portion of the columella auris and ceratohyal persists for some time. The parietotectal and paranasal cartilages are fused together from the very beginning. The processus paroticus originates from the columella auris.In the fully formed stage the notochord is completely embedded in the occipital condyle. The union between the condyle and odontoid process persists. The auditory capsules and occipital arches contribute to the formation of the tectum synoticum plus posterius. The prefacial commissure and facial foramen lie in front of the cochlear portion. The columella auris possesses a processus internus (connected with the quadrate), but the processes a dorsalis has completely disappeared. The orbitotemporal region is quite complete. A medial fenestra is formed in the planum supraseptale. A fenestra is observed in each of the interorbital and nasal septa. The lamina transversalis anterior is fused with the parietotectal cartilage. A complete zona annularis is present. The outer wall of the paranasal cartilage is perforated by a large fenestra lateralis. The parietotectal and paranasal cartilages and the posterior process of the lamina transversalis anterior contribute to the formation of the concha nasalis. There is a contact between the planum antorbitale and nasal septum. The pterygoid process has disappeared. The common characters of the lacertid chondrocranuium are deduced.
    Additional Material: 22 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 138 (1972), S. 187-205 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The day-by-day development of the alimentary system of the sheep embryo from 14 to 34 days is documented and described. This includes development of the mouth, the pharynx and its derivatives, esophagus, stomach, intestine, cecum, pancreas and liver.This work provides standards within the normal range of development of the ovine alimentary system on which studies of abnormal development can be based.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 138 (1972), S. 169-185 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The developmental anatomy of the sheep in the early prenatal period (14 to 34 days) was studied using embryos of known coital age, and embryos of known size with estimated coital age. Characteristics of the embryos were studied by gross observation under the dissecting microscope, and by means of serial sections. The period of the ovum (from conception to 10 days) and the early embryonic period (from 11 to 14 days) are summarized from the literature.This work provides a detailed, systematic account of embryonic development in the sheep and establishes size-age standards. Anatomical features encountered in the normal development of the sheep embryo are documented day-by-day because they are essential for studies of teratogenesis and early prenatal mortality.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Internal vascular ultrastructural detail of renal microcirculation observed by a combination of latex injection/corrosion/scanning electron microscopy techniques can be correlated with structures visible in transmission electron micrographs. Glomeruli of normal and hypertensive rats have been examined using both techniques. In the casts, indentations occur which are comparable in size, shape and frequency to nuclei of endothelial cells; and other irregular indentations may be correlated with the occurrence of platelet thrombi and endothelial cell proliferation. From these observations we conclude that ultrastructurally accurate casts of blood may be visualized by scanning electron microscopy. Such visualization offers much promise for the study of microcirculatory structures in states of disease and altered function.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 10 (1972), S. 38-48 
    ISSN: 1432-0827
    Keywords: Bivalve ; Molluse ; Shell ; Carbonates ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Description / Table of Contents: Résumé La technique du bombardement à l'aide d'ion d'argon est utilisée pour réduire l'épaisseur de la coquille de carbonate de calcium des bivalvesMytilus etMercenaria pour examen au microscope électronique par transmission et en diffraction électronique; une comparaison est réalisée à l'aide de répliques simples, servant de témoins. Les résultats obtenus confirment les études antérieures de répliques et de microscopie par balayage. De plus, une structure “aérée” est mise en évidence dans la coquille des aragonites, et surtout dans le nacre deMytilus. Cette structure est interprêtée comme un artefact induit par la chaleur, formé par l'inclusion d'eau et de matériel organique, interprétation qui concorde avec les études chimiques et de microscopie électronique.
    Abstract: Zusammenfassung Die Beschießung mit Argonionen wurde angewendet, um die Dicke von Calciumcarbonat-Schalen der zweischaligen MuschelnMytilus undMercenaria zu reduzieren. Diese Technik erlaubte die Ausführung von Transmissions-Elektronenmikroskopie und Elektronendiffraktion, wobei gleiche Proben nach einer bereits bestehenden Methode vorbereitet und als Kontrollen herangezogen wurden. Es wurden zusätzliche Resultate zu den Muschelstruktur-studien erhalten, welche früher publizierte Arbeiten unterstützen, die mit der Abklatschmethode und der Raster-Elektronenmikroskopie ausgeführt worden waren. Zusätzlich wurde eine „schaumartige” Struktur der Muschelaragoniten, besonders im Perlmutter vonMytilus, beobachtet. Da es sich um ein durch Hitze verursachtes Artefakt handelt, wird diese Struktur als Einschlüsse von Wasser und organischem Material interpretiert, was den Befunden von verschiedenen veröffentlichten chemischen und elektronenmikroskopischen Arbeiten entspricht.
    Notes: Abstract Use is made of the argon ion-bombardment technique to reduce the thickness of calcium carbonate shells of the bivalvesMytilus andMercenaria for transmission electron microscopy and electron diffraction, with comparison of single-stage replicas of similar specimens serving as controls. As an additional approach to shell structure studies, it gives results which support earlier published work with both replicas and scanning microscopy. In addition, a “frothy” structure is detected in the shell aragonites, especially inMytilus nacre. As a heat-induced artifact, it is interpreted as representing trapped water and organic material inclusions, an interpretation consistent with several published chemical and electron microscope studies.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 21 (1972), S. 68-75 
    ISSN: 1432-0533
    Keywords: Myelinated Nerve ; Venom ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The fine structure of right sciatic nerves of Swiss white mice was studied after being exposed to a venom solution ofAgkistrodon contortrix laticinctus (broad-banded copperhead) and to 0.9% NaCl solutions for periods of 1, 2 or 3 h. There was some “Wallerian-like” degeneration in all groups of nerves in the experiment. Additional neuropathological changes were noted in the nerves exposed to venom solutions. The connective tissue was affected most severely, while the basal lamina was unaffected. Schwann cells were vacuolated, and in the most extreme case, a type of myelin splitting occurred which was considered as a “demyelinative” effect. The results were compared to those of Martin and Rosenberg (1968) [15] on studies of the giant squid axon. References to additional fine structural studies of various other neuropathies were given.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 21 (1972), S. 239-252 
    ISSN: 1432-0533
    Keywords: Ultrastructure ; Myotendon ; Zebra-Bodies (ladder-like structure) ; Rods
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The ultrastructure of the adult and foetal human myotendon is described. At the myotendon the muscle fibre is surrounded by plasma and basement membranes which are never penetrated by the adjacent collagen fibrils of the tendon. Increased thickness and electron density of the plasma membrane and the myofilaments which merge with it occur at the myotendon and this electron dense zone corresponds to the terminal Z-line of the final sarcomere of the myofibril. In the adult the muscle fibre near the myotendon may contain nemaline rods and zebra-bodies. The tendon in the foetus shows much more activity of the fibroblasts than in the normal adult. The collagen fibrils of the early foetus are thinner in diameter than at later stages of development. The union of the tendon with cartilage is illustrated.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 9 (1972), S. 238-242 
    ISSN: 1432-0827
    Keywords: Dentine ; Ultrastructure ; Tubule ; Tooth
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Description / Table of Contents: Résumé L'étude ultrastructurale de la dentine humaine périphérique, de couronnes dentaires de sujets âgés de 11 à 75 ans, a montré trois aspects principaux du contenu des canalicules en coupe transversale. Il s'agit de canalicules apparemment vides, de canalicules contenant un matériel organique annulaire et, enfin, de canalicules totalement remplis d'un matériel organique d'aspect granulaire ou hyalin. Aucune terminaison nerveuse n'est visible à ce niveau.
    Abstract: Zusammenfassung Die ultrastrukturelle Untersuchung von peripherem menschlichem Zahnkronendentin bei Patienten im Alter von 11–75 Jahren hat drei Hauptaspekte des Inhaltes der Dentintubuli gezeigt. Sie bestehen bei transversalen Schnitten aus toten Gängen sowie beim Lumen der Tubuli entweder aus ringförmigen oder ganzausfüllenden Ablagerungen. Im äußeren Dentin wurden keine Nervenendigungen beobachtet.
    Notes: Abstract An ultrastructural study of peripheral human coronal dentin in patients aged 11 to 75 years, has shown main aspects of the dentinal tubular content. In transverse sections, they consist of dead tracts and annular or solid content to the tubular lumen. No nerve endings were observed in the outer dentin.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 77 (1972), S. 279-291 
    ISSN: 1432-1335
    Keywords: Lung mouse tumors ; Chemical carcinogen ; Ultrastructure ; Pneumocyte II ; Crystalline inclusions ; Interstitial fibrosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The pulmonary tumours induced in Swiss mice by NMUR seem to be constituted for the most part by cells closely related to the granular pneumocytes (pneumocytes II ou B). Other rarer cells, of epithelial bronchiolar aspect, may take part in the proliferation. The ultrastructural study of tumoral cells suggest that their secretory functions are disturbed. The origin of the crystalline intratumoral structures is discussed, as well as their possible relationship with the production of surfactant. The peritumoral areas are characterized by a dense interstitial flbrosis in which the collagen fibers are associated with an elastoid substance.
    Notes: Resumé Les tumeurs pulmonaires induites chez la souris swiss par le NMUR apparaissent essentiellement constituées de cellules apparentées aux pneumocytes granuleux (pneumocytes II ou B). D'autres cellules plus rares, de morphologie épithéliale bronchiolaire peuvent participer á la prolifération. L'étude ultrastructurale des cellules tumorales suggère que leurs fonctions secrétoires sont perturbées. Le mode de formation des structures cristallins intratumorales est discuté, ainsi que leur rapport éventuel avec la production du surfactant. Les territoires péri-tumoraux sont caractérisés par une fibrose interstitielle dense où les fibres de collagène sont associées à uns substance élastoïde.
    Type of Medium: Electronic Resource
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