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  • 1980-1984  (1)
  • 1975-1979  (2)
  • 1970-1974  (2)
  • 1880-1889
  • 1980  (1)
  • 1976  (2)
  • 1974  (2)
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Material
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  • 1980-1984  (1)
  • 1975-1979  (2)
  • 1970-1974  (2)
  • 1880-1889
Year
  • 1
    Electronic Resource
    Electronic Resource
    SODIUM AND CHLORIDE FLUXES IN SYNAPTOSOMES IN VITRO (1976)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 26 (1976), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Synaptosomes incubated in a physiological saline extrude sodium and take up potassium. As would be expected this process is completely blocked by metabolic inhibitors such as cyanide and iodoacetate. However, when metabolic inhibitors are replaced by ouabain (100 μM) there is an increase in the steady state intrasynaptosomal sodium and chloride content even though there is no change in the potassium content. The increases are prevented when synaptosomes are incubated with metabolic inhibitors in addition to ouabain. There is therefore a ouabain-insensitive process that transports sodium, chloride and concomitantly water into synaptosomes. It appears not to function when the supply of metabolic energy is inhibited. The diuretic furosemide (1 mM) in the presence of ouabain inhibits the entry of sodium and chloride without affecting the intrasynaptosomal potassium concentration. Ethacrynic acid (1 mM) has a somewhat similar effect but in addition appears to damage the synaptosome membrane.Kinetic measurements were made of the uptake of sodium, potassium and chloride under conditions of metabolic inhibition and the permeability constants of the membrane determined. Values of 0.068, 0.117 and 0.032 × 10-6 (cm s-1) were found for the permeability constants of the membrane to (respectively) sodium, potassium and chloride. Measurements of the rate of uptake in the presence of ouabain revealed an inwardly directed sodium and chloride flux of 5-20 pmol cm-2 s-1. Calculation of the fluxes from the steady state ion concentrations also reveals an inwardly directed sodium and chloride flux, though of lesser magnitude. The influx of water is less than would be expected to preserve osmotic equality suggesting that the translocation of sodium and chloride is the primary event. Although its function remains uncertain the flux has a considerable effect on the ion content of synaptosomes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1976.tb06480.x
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Frequency-Dependent Selection (1974)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Ecology, Evolution, and Systematics 5 (1974), S. 115-138 
    Details
    ISSN: 0066-4162
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.es.05.110174.000555
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
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    THE STUDY OF LAW IN SOCIETY IN BRITAIN (1976)
    Beverly Hills, Calif. : Periodicals Archive Online (PAO)
    Law and society review. 10:4 (1976:Summer) 547 
    Details
    ISSN: 0023-9216
    Topics: Law
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:d430-1976-010-04-000005
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Studies with divinyl ether-maleic anhydride and foot-and-mouth disease vaccines in swine (1974)
    Springer
    Archives of virology 46 (1974), S. 334-340 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Mice treated with divinyl ether-maleic anhydride (DVE/MA) 7 days before, 2 days before, or simultaneously with foot-and-mouth disease (FMD) viral antigens (aqueous or oil emulsified) were more resistant to virus infection and released antibody earlier than mice treated with antigen alone. Simultaneous treatment of swine with these antigens plus DVE/MA resulted in a slightly enhanced early antibody response, which, in a test with oil-emulsified antigen, was not associated with an early induced antiviral resistance to FMD. In general, the primary and secondary antibody responses to oil antigen plus DVE/MA were the same as in control swine receiving the antigen alone. However, swine sensitized with aqueous antigen plus DVE/MA responded faster and developed higher antibody titers after a secondary treatment with aqueous antigen than swine treated similarly but without DVE/MA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01240075
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Book reviews (1980)
    Springer
    Interchange 11 (1980), S. 72-82 
    Details
    ISSN: 1573-1790
    Source: Springer Online Journal Archives 1860-2000
    Topics: Education
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01810434
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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