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  • 1975-1979  (3)
  • 1977  (2)
  • 1975  (1)
Material
Years
  • 1975-1979  (3)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 62 (1975), S. 541-542 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Chromatographia 10 (1977), S. 444-448 
    ISSN: 1612-1112
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary Chiral compounds may be separated by gas chromatography by direct enantiomer separation on optically active stationary phases. More generally the separation can be achieved on conventional stationary phases after formation of diastereoisomeric derivatives. In this work we report on new results in enantiomer separation, indicating that hydrogen bond association is not the only kind of molecular interaction responsible for enantiomer separation. For the separation of a wide variety of chiral compounds with amino or hydroxy groups diastereo-isomeric derivatives may be formed by reaction with L-α-chlorisovaleryl chloride. The derivatives of amino acids, aliphatic and aromatic amines, amino alcohols and of some alcohols are separated in glass capillaries. Gas chromatography as a separation technique of high selectivity is specifically useful for the separation of mixtures of chemically related components with comparable molecular interactions with the molecules of the stationary phase of a gas chromatographic column. The separation of optically active compounds, particularly, requires highly efficient columns. Glass capillary chromatography is a tool that meets this standard and was applied exclusively in this work.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 60 (1977), S. 2071-2078 
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Metabolites from Microorganisms, 6-Chlorogenistein and 6,3′-DichlorogenisteinA strain of Streptomyces griseus produced chlorinated metabolites in media containing soybean meal. Two of these metabolites were isolated together with a chlorine free compound which could be identified as the isoflavone genistein (I) by its spectral properties and by comparison with an authentic sample. By NMR. and mass spectroscopy the chlorinated compounds were shown to be 6-chlorogenistein (II) and 6,3′-dichlorogenistein (III).The 7-glucoside of genistein is a constituent of soybean meal; it is hydrolysed and chlorinated by Streptomyces griseus.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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