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  • 1
    Electronic Resource
    Electronic Resource
    (–)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor (1980)
    [s.l.] : Nature Publishing Group
    Nature 283 (1980), S. 92-94 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The technique used in this study was first to allow slices of CNS tissue to accumulate radiolabelled transmitter and then to examine the effect of GABA and its analogues on the basal and K+-evoked release into fresh superfusion fluid. Three areas of the rat CNS were chosen, the cerebellum, striatum ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/283092a0
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The effect of acute hyperglycaemia on the retinal circulation of the normal cat (1980)
    Springer
    Diabetologia 18 (1980), S. 233-237 
    Details
    ISSN: 1432-0428
    Keywords: Diabetic retinopathy ; glucose ; vessel calibre ; fluorescence angiography ; autoregulation ; cats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The retinal microcirculation of anaesthetised normal cats was studied during hyperglycaemia (15 to 55 mmol/l) induced by intravenous infusion of glucose, using high speed cine fluorescence angiography. Saline (0.150 mmol/l) was infused as a control for the volume effect of glucose solution and equiosmolar mannitol was infused as a control for the osmotic effect. The mean retinal arteriolar inflow rate increased from 34±1 mm/sec to 41±4 mm/sec during glucose infusion, and from 46±1 mm/sec to 56±3 mm/sec during mannitol infusion. The blood pressure similarly increased from 105±5 mmHg to 125±2 mmHg during glucose infusion and from 110 ±7 mmHg to 129±1 mmHg during mannitol infusion. During mannitol infusion the increased inflow was accompanied by a reduction in the arteriolar width so that the volume flow remained unchanged. During glucose infusion this constriction did not occur, resulting in a significantly increased volume of retinal blood flow (9±1 μl/min to 12±1 μl/min).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00251922
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Increased somatomedin and cartilage metabolic activity in rabbit fetuses injected with insulin in utero (1980)
    Springer
    Diabetologia 19 (1980), S. 143-147 
    Details
    ISSN: 1432-0428
    Keywords: Rabbit fetus ; insulin ; somatomedin activity ; cartilage growth
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of insulin injection in fetal rabbits on plasma somatomedin activity and cartilage metabolism was investigated. One fetus in each of 12 litters was injected with 1 unit of insulin zinc suspension subcutaneously on day 27 of gestation and a control fetus was injected with the same volume of 0.154 mol/l saline. The litter was delivered by caesarean section on day 29 and each fetus identified. Plasma somatomedin activity was determined by fetal rabbit cartilage bioassay. Costal cartilage from individual fetuses was incubated in medium containing [3H]thymidine or [35S]sulphate as indicators of cell replication and matrix synthesis respectively. Individual values for somatomedin activity or cartilage isotope uptake were ranked within a litter. In each case the rank in the litter of the insulin-injected fetus, but not the saline-injected fetus, was significantly higher than the mean rank of the litter. Insulin did not stimulate cartilage metabolism in vitro.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00421861
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    The understanding in science test as a measure of piagetian level of intellectual development (1980)
    Springer
    Research in science education 10 (1980), S. 83-91 
    Details
    ISSN: 1573-1898
    Source: Springer Online Journal Archives 1860-2000
    Topics: Natural Sciences in General
    Notes: Conclusion The purpose of this paper is not to denigrate pencil-and-paper tests of intellectual capabilities. The Understanding in Science Test, if it were not for its reliability problems, may be a useful test of intellectual processing. It appears not to be a successful analogue to clinically-administered Piagetian tasks. The same may be said of the other written or group tests of this nature. If they are reliable, they may provide useful measures of intellectual ability. Our research, though, suggests that, for junior high school students and younger, they may not possess high concurrent validity with Piagetian tasks.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02356313
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Eighteen years on (1980)
    Springer
    Medical & biological engineering & computing 18 (1980), S. N20 
    Details
    ISSN: 1741-0444
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02442472
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  • 6
    Electronic Resource
    Electronic Resource
    Millimeter wave absorption spectra of biological samples (1980)
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 1 (1980), S. 285-298 
    Details
    ISSN: 0197-8462
    Keywords: absorption ; millimeter wave ; biological media ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: A solid-state computer-controlled system has been used to make swept-frequency measurements of absorption of biological specimens from 26.5 to 90.0 GHz. A wide range of samples was used, including solutions of DNA and RNA, and suspensions of BHK-21/C13 cells, Candida albicans, C krusei, and Escherichia coli. Sharp spectra reported by other workers were not observed. The strong absorbance of water (10-30 dB/mm) caused the absorbance of all aqueous preparations that we examined to have a water-like dependence on frequency. Reduction of incident power (to below 1.0 μW), elimination of modulation, and control of temperature to assure cell viability were not found to significantly alter the water-dominated absorbance. Frozen samples of BHK-21/C13 cells tested at dry ice and liquid nitrogen temperatures were found to have average insertion loss reduced to 0.2 dB/cm but still showed no reproducible peaks that could be attributed to absorption spectra. It is concluded that the spectral resonances reported by others are likely to be in error.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bem.2250010305
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Dosimetry for a study of effects of 2.45-GHz microwaves on mouse testis (1980)
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 1 (1980), S. 325-336 
    Details
    ISSN: 0197-8462
    Keywords: microwave ; dosimetry ; mouse testis ; 2.45 GHz ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: In order to determine the effects of microwave radiation on the testis, it is necessary to express the physical insult in animal studies in a way that can be replicated elsewhere and ultimately used as a basis for extrapolation to man. However, there is conflict  -  especially in chronic experiments  -  between the desire for precise dosimetry and the need to minimise alteration of the normal physiological functions of the animals. The compromise arrangement used in this study was to house the mice singly, in cages with limited food and water, and to irradiate them for up to 30 days (16 h/day) in an anechoic chamber. The only measurements taken routinely were of power density in the positions normally occupied by the cages. In addition, a series of absorption measurements was made in mouse carcasses: Whole-body specific absorption rate (SAR); energy-deposition patterns (determined thermographically); and local SAR in testis (using a miniature electric (E)-field probe). It was concluded that the SAR in testis was considerably less than the whole-body SAR. Exposure for 16 h at 50 mW/cm2 elevated rectal but not testis temperature, thus demonstrating the ability of the conscious mouse to regulate the temperature of its testis.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bem.2250010308
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    Paper (German National Licenses)
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