ISSN:
1432-041X
Keywords:
Hydra
;
Morphogenetic substances
;
Regeneration
;
Pattern formation
;
Sea anemones
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary A substance was isolated from crude extracts of hydra that inhibits foot regeneration. This substance, the foot inhibitor, has a molecular weight of ≦500 daltons. It is a hydrophilic molecule, slightly basic in character and it has no peptide bonds. The pruified substance acts specifically and at concentrations lower than 10−7 M. At this low concentration only foot and not head regeneration is inhibited. Hydra are sensitive to purified foot inhibitor between the second and eight hour after initiation of foot regeneration by cutting. In normal animals the foot inhibitor is most likely produced by nerve cells. A substance with similar biological and physico-chemical properties is found in other coelenterates.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00848805
Permalink
