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  • 1
    Electronic Resource
    Electronic Resource
    VIP occurs in intrathyroidal nerves and stimulates thyroid hormone secretion (1980)
    [s.l.] : Nature Publishing Group
    Nature 287 (1980), S. 343-345 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Thyroid tissue specimens from cat, pig and man were fixed by immersion in ice-cold 4% formalin buffered to pH 7.O. The human material was obtained at surgery for benign autonomous nodules. Mice, rats and guinea pigs were anaesthetized with sodium pentobarbitone or diethyl ether and perfused via the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/287343a0
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Vasoactive intestinal peptide (VIP) occurs in nerves of the pineal gland (1980)
    Springer
    Cellular and molecular life sciences 36 (1980), S. 1119-1120 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Nerves staining with antibodies against vasoactive intestinal peptide (VIP) were detected in the pineal gland of the rabbit, cat and pig. VIP nerves were numerous in the cat but few in the rabbit and pig. A particularly rich VIP nerve supply was noted in the pineal stalk of the cat. The nerves were predominantly located around small blood vessels. Occasionally, nerve fibres were seen in the glandular parenchyma without obvious relation to blood vessels.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01966004
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Quinacrine accumulates in certain peptide hormone-producing cells (1980)
    Springer
    Histochemistry and cell biology 66 (1980), S. 1-9 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Quinacrine is a fluorescent anti-malarial acridine derivative which binds selectively to a population of nerves, presumably peptidergic, and to certain peptide hormone-producing cells. Among these cells are glycopeptide hormone-producing cells in the adenohypophysis, the calcitonin cells in the thyroid, the insulin, glucagon and PP cells in the pancreatic islets, and the gastrin cells in the pyloric antrum. Available evidence suggests that the fluorophore accumulates in the secretory granules. The half-life of the fluorescence varies from one cell type to another, from 6 h in the gastrin cells to 40 h in the insulin cells. It cannot be excluded that the half-life of the fluorescence reflects the turn-over rate of the secretory granules and that the disappearance rate of the fluorescence is dependent upon the secretory activity of the cell.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00493240
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Ontogeny and ultrastructure of somatostatin and calcitonin cells in the thyroid gland of the rat (1980)
    Springer
    Cell & tissue research 206 (1980), S. 193-201 
    Details
    ISSN: 1432-0878
    Keywords: Somatostatin cells ; Calcitonin cells ; Ontogeny ; Ultrastructure ; Thyroid (rat)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Calcitonin cells are relatively numerous in the thyroid gland of the rat. In contrast, somatostatin cells are very scarce except at the time of birth and a few days thereafter, when they are conspicuously numerous. Somatostatin cells of the thyroid gland, which are ultrastructurally similar to somatostatin cells in gut and pancreas, also contain immunoreactive calcitonin. It is not clear whether somatostatin cells in the rat thyroid gland produce calcitonin or accumulate calcitonin from the environment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00232763
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Evidence that lipolytic peptide B occurs in the ACTH/MSH-cells of the pituitary and in the brain (1980)
    Springer
    Cell & tissue research 205 (1980), S. 349-359 
    Details
    ISSN: 1432-0878
    Keywords: Lipolytic peptide B ; Pituitary ; ACTH/MSH cells ; Brain ; Immunocytochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Several lipid-mobilizing peptides occur in the pituitary, among them β-lipotropin and “lipolytic peptide A and peptide B”. The latter two peptides are distinct from β-lipotropin and appear to be chemically related to the neurophysins. Immunohistochemistry has now revealed that the lipolytic peptide B of the pituitary is localized in the ACTH- and MSH-cells. In addition, immunoreactive peptide B was found in axons of the posterior lobe of the pituitary. Immunoreactive peptide B was found also in nerve fibers and nerve cell bodies in the hypothalamus, particularly in the hypothalamo-hypophyseal tract and in the magnocellular neuronal system. Immunoreactive nerve fibers were numerous also in the periventricular nucleus of the thalamus. The antiserum against peptide B cross-reacts with neurophysin I, and hence, it cannot be excluded that at least part of the immunostaining in the brain reflects the presence of the latter component. However, the regional distribution of immunoreactive peptide B and neurophysin was not identical. Therefore, it is possible that authentic peptide B occurs not only in the pituitary but also in the brain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00232277
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Origin and distribution of VIP (Vasoactive Intestinal Polypeptide)-nerves in the genito-urinary tract (1980)
    Springer
    Cell & tissue research 205 (1980), S. 337-347 
    Details
    ISSN: 1432-0878
    Keywords: VIP-immunoreactive nerves ; Genito-urinary tract ; Peptidergic nerves ; Neuropeptides
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary VIP (Vasoactive Intestinal Polypeptide)-immunoreactive nerves were found throughout the genito-urinary tract of the cat; they were less numerous in the guinea pig and in the rat. In the cat, VIP nerves were particularly numerous in the neck of the urinary bladder and proximal urethra, in the uterine cervix and in the prostate gland. The nerves were found in smooth muscle, around blood vessels and in the connective tissue immediately beneath the epithelium. Ganglia were found below the trigonum area of the bladder, in the wall of the proximal urethra, and in paracervical tissue. VIP-immunoreactive nerve cell bodies occurred in all these ganglionic formations. These ganglia probably represent the origin of the VIP nerves of the genital tract since their removal in the female cat greatly reduced the VIP nerve supply. Transection of the hypogastric nerves had no overt effect. Transection of the cervix eliminated the VIP nerves above the level of the lesion, except those in the ovaries, supporting the view that the VIP nerves of the uterus and the oviduct are derived from a paracervical source.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00232276
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    Paper (German National Licenses)
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