ISSN:
1432-2307
Keywords:
Granular cell myoblastoma
;
Granular cell tumor
;
Peripheral nerve
;
Immunoperoxidase
;
Electron microscopy, Schwann cell
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The histologic, immunohistochemical and ultrastructural characteristics of two granular cell tumors arising from the right recurrent laryngeal and left facial nerves are described. S-100 protein was detected both in the nuclei and cytoplasm of the granular cells using the peroxidase-anti-peroxidase method. The ultrastructural findings in both cases support a Schwann cell derivation of the granular cells. It is suggested that the granularity of cells of granular cell tumor may represent a lysosomal disorder affecting most frequently neoplastic and nonneoplastic Schwann cells and occasionally other cells.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00695059
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