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  • 1
    Electronic Resource
    Electronic Resource
    Granular cell tumor arising in myelinated peripheral nerves (1983)
    Springer
    Virchows Archiv 402 (1983), S. 175-183 
    Details
    ISSN: 1432-2307
    Keywords: Granular cell myoblastoma ; Granular cell tumor ; Peripheral nerve ; Immunoperoxidase ; Electron microscopy, Schwann cell
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The histologic, immunohistochemical and ultrastructural characteristics of two granular cell tumors arising from the right recurrent laryngeal and left facial nerves are described. S-100 protein was detected both in the nuclei and cytoplasm of the granular cells using the peroxidase-anti-peroxidase method. The ultrastructural findings in both cases support a Schwann cell derivation of the granular cells. It is suggested that the granularity of cells of granular cell tumor may represent a lysosomal disorder affecting most frequently neoplastic and nonneoplastic Schwann cells and occasionally other cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00695059
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Malignant lymphoma with a high content of epithelioid histiocytes (so-called Lennert's lymphoma) (1983)
    Springer
    Virchows Archiv 399 (1983), S. 255-264 
    Details
    ISSN: 1432-2307
    Keywords: Non-Hodgkin's lymphoma ; Lennert's lymphoma ; Epithelioid histiocyte ; Cytoplasmic immunoglobulins ; Ultrastructure of Lennert's lymphoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The clinicopathological findings of four cases of an uncommon form of non-Hodgkin's lymphoma called malignant lymphoma with a high content of epithelioid histiocytes (MLHH) are described. In each case the peroxidase antiperoxidase technique was used for detecting cytoplasmic immunoglobulins (CIg) in the diagnostic lymphoid tissue. In one case (patient 1), IgG and IgM heavy chains and kappa light chain were detected in 30 to 40 percent of the atypical lymphoid cells. This result suggests that the proliferating B lymphocytes in this patient with MLHH are neoplastic rather than reactive in nature. We were unable to identify CIg in the proliferating lymphoid cells of the other three patients. Our case when coupled with others reported in the literature suggest that the morphologic features of MLHH (so-called Lennert's lymphoma) can be associated with a neoplastic proliferation of either T or B lymphocytes. The ultrastructural findings of one case are presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00612943
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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