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  • 1
    Electronic Resource
    Electronic Resource
    Buchbesprechungen (1985)
    Springer
    Journal of molecular medicine 63 (1985), S. 480-480 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01731498
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Changing biclonal gammopathy due to different lymphocyte clones in acquired immunodeficiency syndrome with kaposi's sarcoma (1985)
    Springer
    Journal of molecular medicine 63 (1985), S. 1083-1086 
    Details
    ISSN: 1432-1440
    Keywords: Acquired Immunodeficiency-Syndrome ; Kaposi's sarcoma ; Biclonal gammopathy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We report the first case of acquired immunodeficiency-syndrome (AIDS) with Kaposi's sarcoma which at the same time has also a changing biclonal gammopathy (initial: double IgG-paraproteinaemia, lateron IgA-IgG Double-paraproteinaemia) due to different lymphocyte clones. The relationship of a B-cell neoplasia to a concurrent disease of T-cells is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01739678
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Zur Pathogenese und klinischen Bedeutung der Mönckebergschen Mediaverkalkung (1985)
    Springer
    Journal of molecular medicine 63 (1985), S. 211-216 
    Details
    ISSN: 1432-1440
    Keywords: Mönckeberg's sclerosis ; Lumbar sympathectomy ; Doppler ankle pressures ; Peripheral vessel disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Medial calcinosis of Mönckeberg is frequently observed in peripheral arteries of diabetics with neuropathy. The cause of this vessel alteration is unknown and the clinical significance has been questioned. Six to eight years after uni- or bilateral lumbar sympathectomy 60 patients were investigated radiologically for medial calcinosis of foot arteries. Of 60 patients, 55 had Mönckeberg's sclerosis. In 93% of the patients who had undergone bilateral operation medial calcification was seen in both feet. After unilateral sympathectomy the incidence of medial calcinosis on the operated side was significantly higher than on the non-operated side (88% versus 18%,p〈0.01). There was no significant difference between diabetics and non-diabetics. These findings suggest that medial calcification is related to autonomic neuropathy of peripheral vessels. Fifty-two of 160 patients (32.5%) with severe arterial occlusive disease of the lower limbs showed medial calcification of foot arteries. Mönckeberg's sclerosis was significantly associated with the peripheral type of vascular disease (p〈0.025). Two groups of patients with the same stage of occlusive vascular disease but without (group A) and with (group B) medial calcification were examined by Doppler ultrasound. In group A the mean ankle pressure (pD) was 51 mm Hg lower than the Riva-Rocci pressure (pRR). In spite of the severe ischemia mean pD in group B exceeded pRR by 14 mm Hg. Of the patients of group B 63% had a pD-pRR value ≧0 mm Hg. In group A no positive difference pD-pRR could be shown. Thus medial calcification can cause pseudohypertensive Doppler pressures and mask vessel disease. It might play a role in the development of the peripheral type of arteriosclerosis of the lower limbs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01731171
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  • 4
    Electronic Resource
    Electronic Resource
    IgG-antibodies to HTLV-III in patients with AIDS, LAS, and persons at risk of AIDS in West Germany (1985)
    Springer
    Annals of hematology 50 (1985), S. 13-18 
    Details
    ISSN: 1432-0584
    Keywords: HTLV-III antibodies ; AIDS ; lymphadenopathy syndrome ; homosexuals at risk of AIDS ; ELISA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In a first seroepidemiological study on the prevalence of the human T-lymphotropic retrovirus HTLV-III in West Germany, sera of 26 patients with acquired immunodeficiency syndrome (AIDS), 33 patients with lymphadenopathy syndrome (LAS) or AIDS related complex (ARC), and 113 homosexual men at risk of AIDS were screened for IgG antibodies to HTLV-III by an enzyme linked immunosorbent assay (ELISA). 22 out of 26 AIDS-patients (84.6%), 24 out of 33 LAS-patients (72.7%), and 44 out of 113 healthy homosexual men with increased risk of AIDS (38.9%) were found positive for antibodies to HTLV-III. Heterosexual controls including healthy laboratory workers and medical personnel with contact to AIDS patients did not show antibodies to HTLV-III. The HTLV-III antibodies analyzed predominantly recognize a protein of molecular weight 41,000 (p 41).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00319764
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  • 5
    Electronic Resource
    Electronic Resource
    Prevalence of antibodies to human T-lymphotropic virus-III (HTLV-III) in hemopheliacs and other patients chronically substituted with blood products (1985)
    Springer
    Annals of hematology 51 (1985), S. 243-249 
    Details
    ISSN: 1432-0584
    Keywords: HTLV-III infection ; AIDS ; Hemophilia ; Polytransfused patients
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The prevalence of antibodies to human T-lymphotropic virus III (HTLV-III) was determined in a total of 140 hemophiliacs and 36 polytransfused patients from three medical centers by an enzyme linked immunosorbent assay (ELISA) and confirmatory tests. 58 hemophiliacs (41.4%) were seropositive. In all instances where the origin of the coagulation factors given to these patients could be determined, blood products came from the United States. In addition, 2 of 36 polytransfused patients, mostly with acute leukemias, who were transfused with blood products from local donors were positive for HTLV-III antibodies. No HTLV-III antibodies were detected in 237 blood donors selected in part from the donor pool of the polytransfused patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00320518
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    Paper (German National Licenses)
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