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  • 1995-1999
  • 1985-1989  (3)
  • 1975-1979
  • 1988  (3)
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  • 1995-1999
  • 1985-1989  (3)
  • 1975-1979
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  • 1
    Electronic Resource
    Electronic Resource
    On the directional sensitivity of hot-wires: a new look at an old phenomenon (1988)
    Springer
    Experiments in fluids 6 (1988), S. 553-560 
    Details
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The directional response of a constant temperature hotwire anemometer to variations in pitch and yaw is reviewed, and a new data reduction technique for obtaining velocity vector data in a steady flow is described. Sequential sampling of the signal as the probe shaft is rotated through 360° provides data to yield a three-dimensional velocity vector. Jorgensen's expression was found to be suitable for the data reduction using independently measured pitch and yaw coefficients. Within the range of velocity and flow direction investigated, the velocity magnitude and direction can be determined to within 2% and 2° respectively if the yaw coefficient is neglected. This measurement method is currently being used to determine velocity distributions on the intake-valve/cylinder boundary for different induction system designs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00196602
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Effects of fosfomycin, mesna, and sodium thiosulfate on the toxicity and antitumor activity of cisplatin (1988)
    Springer
    Journal of cancer research and clinical oncology 114 (1988), S. 497-501 
    Details
    ISSN: 1432-1335
    Keywords: Cisplatin ; Fosfomycin ; Mesna ; Sodium-thiosulfate ; Detoxification ; Antitumor effect
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fosfomycin and mesna were investigated in rats and mice concerning their detoxifying effects on cisplatin toxicity in comparison to sodium thiosulfate, a known protector against cisplatin nephrotoxicity. After separate i.p. injection of cisplatin and fosfomycin (500 mg/kg) or mesna (800 mg/kg) a slight increase in the 50% lethal dose of cisplatin was found in all animals. In mice sodium thiosulfate proved to be far more effective in preventing lethal toxicity and nephrotoxicity as measured by blood urea nitrogen increase. Fosfomycin and mesna were almost without influence on cisplatin treatment of L-1210 leukemia whereas their inhibition of the antitumor effect against S-180 ascites sarcoma (increase of in cisplatin dose to cure 50% of animals from 2.0 mg/kg to 3.5/4.7 mg/kg cisplatin) was similar to thiosulfate, which showed a strong inhibiting effect in the treatment of both tumors. In rats fosfomycin distinctively reduced the antitumor efficacy of cisplatin against Yoshida ascites sarcoma. Thus the concurrent injection of fosfomycin and mesna reduced both the toxicity and the antitumor activity of cisplatin. Therefore their simultaneous administration in addition to cisplatin via the same injection route should be avoided. Due to the weak detoxifying efficacy of fosfomycin and mesna they cannot be used instead of sodium thiosulfate for renal protection against cisplatin toxicity in local i.p. treatment modalities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00391499
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Exercise versus immersion: antagonistic effects on water and electrolyte metabolism during swimming (1988)
    Springer
    European journal of applied physiology 57 (1988), S. 248-253 
    Details
    ISSN: 1439-6327
    Keywords: Aldosterone ; Antidiuretic hormone ; Blood volume ; Kidney
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Changes in blood composition, renal function, aldosterone and antidiuretic hormone (ADH) concentrations were investigated in 10 untrained male subjects when swimming (60 min at a heart rate of about 155 beats·min−1, water temperature 28° C) and during the subsequent 3 h in a sitting position. Many specific effects of either exercise or immersion were abolished or attenuated; no significant changes in plasma aldosterone, [ADH], [K+], [Cl−], or of urinary volume, glomerular filtration rate, free water or osmolar clearance were observed. The urine was diluted resulting in lowered [Na+]. In blood some quantities which are only slightly influenced by immersion increased during swimming ([Na+], [Lac−], [H+], osmolality, [creatinine]). Exercise induced plasma volume loss, calculated from increasing [Hb], was small (110 ml), probably because interstitial fluid enters the vascular space during the initial phase of immersion. One might anticipate that the training effects on fluid and electrolyte metabolism and circulation are different when swimming and when performing endurance sports on land.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00640671
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    Paper (German National Licenses)
    Fulltext
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