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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 72 (1994), S. 772-774 
    ISSN: 1432-1440
    Keywords: Type A natriuretic peptide (CDD/ ANP-99-126) ; Bronchodilation ; Asthma therapy ; Lung function
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Type A natriuretic peptide (CDD/ANP99-126) in its circulating form was analyzed with respect to the localization of its bronchodilating effects in asthmatic subjects in vivo. The intravenous infusion of 5.7, 11.4, and 17.1 pmol kg−1 min− CDD/ANP-99-126 caused a significant bronchodilation of both central and peripheral airways. While the localization of the bronchodilating effects was similar to β2-agonists, an improvement in lung function parameters comparable to these substances was not observed. But other members of the natriuretic peptide family may reveal a stronger bronchodilating potency.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Intensivmedizin und Notfallmedizin 36 (1999), S. 190-196 
    ISSN: 1435-1420
    Keywords: Key words Pulmonology ; Pneumology ; Respiratory care ; Intensive care medicine ; Schlüsselwörter Pneumologie ; Intensivmedizin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Im Rahmen einer Fragebogenaktion wurde der Stand der Intensiv-Versorgung an Kliniken mit in der Deutschen Gesellschaft für Pneumologie (DGP) organisierten Pneumologen untersucht. Dazu wurden sämtliche eingetragenen Mitglieder der DGP zur Situation an der Klinik, an der sie arbeiten, befragt. Von mehr als 1600 angeschriebenen Ärzten antworteten 240, die 145 verschiedene Kliniken repräsentieren (Rücklaufquote: 14,4%). Analysiert wurden die Anzahl und Art der Einrichtungen, die pneumologische Gesamt- und Intensivbettenzahl und das pneumologisch-intensivmedizinische Leistungsspektrum. Auch wenn der Anteil pneumologischer Intensivbetten an der Gesamtzahl pneumologischer Betten an Universitätskliniken genau so hoch liegt wie an Lungenkliniken, finden sich weder an Universitätskliniken (8%) noch an Versorgungskrankenhäusern (2%) eine akzeptable Anzahl pneumologisch verantworteter Intensivbetten, und selbst an Lungenkliniken (50%) wird nur ein Teil der Intensivstationen durch Pneumologen geleitet. Pneumologen haben in Deutschland bezogen auf die Gesamtzahl der internistischen Intensivbetten so gut wie nichts mit der Intensiv-Versorgung zu tun. Das in Deutschland bestehende Defizit in der Präsenz von Pneumologie an Universitätsklinika und an den anderen Krankenhäusern spiegelt sich – im Gegensatz zu anderen Ländern – in besonderer Weise in der internistischen Intensivmedizin wider.
    Notes: Summary With a postal survey we investigated the situation of intensive care medicine in hospitals where pneumologists organized in the German Society of Pneumology (DGP) are employed. Of more than 1600 interviewed 240 responded, representing 145 different hospitals (overall response rate 14.4%). All members of the DGP were questionaired about the type of hospital, the organization, and size of the department of respiratory medicine (independent, semi-independent, or not independent at all) as well as the organization and size of the intensive care units at their respective hospitals. In addition to this the technical resources available were investigated. Even though the fractions of intensive care beds of the total number of respiratory care beds are equal in university hospitals and specialized pulmonary care centers the part of intensive care units that are headed by pneumologists are inadequately low in university (8%) as well as general type hospitals (2%) and even in specialized respiratory care centers (45%) only part of the ICUs are run by pneumologists. In Germany – in contrast to other countries – the existing deficit of respiratory care medicine at university hospitals is reflected in an even aggravated fashion in the lack of involvement in intensive care medicine.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 57 (1988), S. 248-253 
    ISSN: 1439-6327
    Keywords: Aldosterone ; Antidiuretic hormone ; Blood volume ; Kidney
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Changes in blood composition, renal function, aldosterone and antidiuretic hormone (ADH) concentrations were investigated in 10 untrained male subjects when swimming (60 min at a heart rate of about 155 beats·min−1, water temperature 28° C) and during the subsequent 3 h in a sitting position. Many specific effects of either exercise or immersion were abolished or attenuated; no significant changes in plasma aldosterone, [ADH], [K+], [Cl−], or of urinary volume, glomerular filtration rate, free water or osmolar clearance were observed. The urine was diluted resulting in lowered [Na+]. In blood some quantities which are only slightly influenced by immersion increased during swimming ([Na+], [Lac−], [H+], osmolality, [creatinine]). Exercise induced plasma volume loss, calculated from increasing [Hb], was small (110 ml), probably because interstitial fluid enters the vascular space during the initial phase of immersion. One might anticipate that the training effects on fluid and electrolyte metabolism and circulation are different when swimming and when performing endurance sports on land.
    Type of Medium: Electronic Resource
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