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  • 1990-1994  (4)
  • 1994  (4)
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  • 1990-1994  (4)
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  • 1
    Electronic Resource
    Electronic Resource
    Severe neurological abnormalities associated with a mutation in the zinc-finger domain in a group A xeroderma pigmentosum patient (1994)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 131 (1994), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: All the reported Japanese patients with group A xeroderma pigmentosum (XP) have two or three mutations at codon 116 in exon 3, codon 228 in exon 6, and the splicing acceptor site of intron 3 of XP group A complementing (XPAC) gene. A homozygote (XP390S) with a nonsense mutation at codon 228 has less severe neurological abnormalities than patients with the splicing mutation at the acceptor site of intron 3. As homozygotes for the nonsense mutation at codon 116, which truncates a carboxyl-terminal site of XPAC protein at an early part of its zinc-finger domain, have not been reported previously, the possible severity of associated neurological abnormalities was not known. We report a group A XP patient, XP180S, who had neurological abnormalities which were more severe than those in patients homozygous for the splicing mutation. The polymerase chain reaction product from exon 3 of the patient's XPAC gene was digested completely into three fragments by MseI restriction endonuclease. Thus, the patient was homozygous for the mutation at codon 116.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1994.tb08562.x
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  • 2
    Electronic Resource
    Electronic Resource
    Plane elastic solution for the second mixed boundary value problem and its application (1994)
    Springer
    Archive of applied mechanics 64 (1994), S. 295-306 
    Details
    ISSN: 1432-0681
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Übersicht Die Lösung des zweiten gemischten Randwertproblems der ebenen Elastizität mit zwei kraftbeanspruchten und zwei gestützten Rändern wird dargestellt. Für die Analyse wird eine rationale Abbildung verwendet, die als Summe partieller Lösungen aus komplexen Spannungsfunktionen aufgebaut ist. Für gleichmäßige Zug- und Schubbeanspruchungen kann die Lösung in geschlossener Form dargestellt werden und ist verwendbar in Rißaufgaben der linear elastischen Bruchmechanik. Als Illustration der allgemeinen Lösung dient ein verzweigter Bereich der gegenseitigen Einwirkung einer quadratischen Öffnung mit Seitenkerbe und eines Risses. Die Spannungsverteilungen und Spannungsintensitäten werden dabei berechnet.
    Notes: Summary A solution is obtained for the second mixed boundary value problem with two boundaries loaded with external forces, and the other two boundaries simply supported. A rational mapping function formed as a sum of fractional expressions and complex stress functions is used for the analysis. A closed form solution can be obtained under uniform tensile and shearing loadings. These solutions are applicable to crack problems in linear elastic fracture mechanics. In order to illustrate the general solution, a double connected region is considered, in which interaction between a square hole with a crack extension and another crack is investigated. Stress distributions and stress intensity factors are obtained.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00788215
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Rheological properties of blends of lithium- or sodium-sulfonated polystyrene ionomers with polyamide 6 (1994)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 34 (1994), S. 1056-1064 
    Details
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Dynamic viscoelastic properties of blends of alkali metal salts of sulfonated polystyrene ionomers with polyamide 6 were investigated in the melt. The blends of lithium-sulfonated polystyrene (10 mol% sulfonation) with polyamide 6 (LiSPS/PA-6) behaved as a homogeneous viscoelastic fluid over most of the blend composition range, since blending with PA-6 disrupted the ionic network of the LiSPS. Specific interactions between the lithium sulfonate group and the amide group are believed to be responsible for the behavior. By contrast, blends of sodium-sulfonated polystyrene with PA-6 (NaSPS/PA-6) showed typical behavior of immiscible systems in that they exhibited large positive deviations from the log-additivity rule for complex viscosity. This implied that sodium sulfonate groups did not interact strongly with amide groups, in contrast to the behavior of lithium sulfonates. Oldroyd's emulsion model was applied to the results of dynamic viscoelasticity studies of both the immiscible ionomer/PA-6 blends and the polystyrene/PA-6 blends. For the latter, the fit was much better than for the former. This difference in behavior might be due to partial miscibility or to the presence of an indistinct phase boundary in the “immiscible” ionomer-based systems.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pen.760341304
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Direct observation of the coil-globule transition in dna molecules (1994)
    New York : Wiley-Blackwell
    Biopolymers 34 (1994), S. 555-558 
    Details
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bip.360340410
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    Paper (German National Licenses)
    Fulltext
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