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  • 1
    Electronic Resource
    Electronic Resource
    Solid-pseudopapilläre Tumoren des Pankreas (1996)
    Springer
    Der Chirurg 67 (1996), S. 1012-1015 
    Details
    ISSN: 1433-0385
    Keywords: Key words: Papillary cystic tumor ; Pancreas ; Pancreatic neoplasms.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung. Wir berichten über unsere Erfahrungen an 3 Patientinnen mit einem solid-pseudopapillären Tumor des Pankreas. Charakteristisch für diesen semimalignen Tumor sind das Vorkommen bei jungen Frauen, die auffallende Größe (bis 10 cm) und das seltene Auftreten von Metastasen. Trotz erheblicher Größe der Tumoren war in allen Fällen eine kurative Resektion möglich. Präoperatives Hauptunterscheidungsmerkmal zum duktalen Adenocarcinom war in allen Fällen die normale Weite des Pankreasgangs ohne Gangabbruch. Im Gegensatz zu den meisten anderen Tumoren des Pankreas hat dieser Tumor eine gute Prognose. Alle unsere Patientinnen sind z. Z. (bis zu 8 Jahren nach der Operation) rezidivfrei.
    Abstract: Schlüsselwörter: Solid-pseudopapillärer Tumor – Pankreas – papillär-cystischer Tumor
    Notes: Summary. We report on three female patients with solid pseudopapillary tumors of the pancreas. The histogenetic origin of this entity is still unclear. The tumor, usually occurring in young women, forms large masses (up to 10 cm in diameter) before becoming symptomatic. Metastases have very rarely been reported. In contrast to other pancreatic tumors, the main pancreatic duct was displaced, but of normal caliber without stenosis, in all our patients. Despite the large size of the tumors, they were curatively resected in all three cases. Two of the tumors infiltrated the parenchyma or adipose tissue of the pancreas but did not spread into the lymph nodes or other organs. All of the patients are alive and without signs of tumor recurrence up to 8 years after surgical resection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00002511
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  • 2
    Electronic Resource
    Electronic Resource
    Reversible metastatic pulmonary calcification in a patient with multiple myeloma (1996)
    Springer
    Annals of hematology 72 (1996), S. 329-332 
    Details
    ISSN: 1432-0584
    Keywords: Key words Bisphosphonate ; Multiple myeloma ; Pulmonary calcification
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  A-52-year-old patient presented with a 2-year history of multiple myeloma, recurrent episodes of hypercalcemia, and extensive bone involvement. She developed pulmonary infiltrates, initially misdiagnosed as interstitial pneumonia. High-resolution computed tomography and bone scintiscanning indicated pulmonary calcification, which was confirmed by a transbronchial biopsy. Cytostatic treatment of multiple myeloma in combination with repetitive i.v. administration of bisphosphonates over a period of 6 months led to a significant improvement of clinical symptoms. Regression of pulmonary infiltrates was demonstrated by chest radiograph and computed tomography. There are only a few reports on pulmonary calcification in patients with multiple myeloma; the condition was associated mostly with progressive disease, kidney failure, adult respiratory distress syndrome and bad prognosis. In our patient isolated calcification of the lungs without involvement of other organ systems was successfully treated. These findings suggest that interstitial pulmonary calcinosis in multiple myeloma can be reversed by normalization of serum calcium levels using bisphosphonates combined with cytostatic treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002770050181
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    MR mammography: influence of menstrual cycle on the dynamic contrast enhancement of fibrocystic disease (1999)
    Springer
    European radiology 9 (1999), S. 1107-1112 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Breast ; Parenchymal pattern ; MR imaging ; Contrast enhancement ; MR mammography ; Menstruation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Magnetic resonance mammography (MRM) provides data regarding the nature of tumours based on contrast medium dynamics; fibrocystic changes in the breast, however, may lead to false-positive results. This study investigated whether the contrast medium dynamics of fibrocystic changes are dependent on the menstrual cycle. Twenty-four patients with palpable lumps but normal mammographies and ultrasound studies were examined. The MRM technique was performed during the first and second part of the menstrual cycle using a FLASH 3D sequence, both native and at 1, 2, 3 and 8 min after intravenous application of 0.15 mmol/kg body weight of gadodiamide. The calculated time–intensity curves were evaluated based on the following criteria: early percentage of contrast medium uptake in relation to the native value; formation of a plateau phenomenon after the second minute; the point of maximal contrast medium uptake; and calculation of the contrast enhancing index. During the second half of the menstrual cycle, a generally greater contrast medium uptake was observed. Nevertheless, when further diagnostic criteria, such as continuous contrast medium increase as a function of time, were considered, there was no increased rate of false-positive findings. The phase of the menstrual cycle may affect the specificity of the examination, if only the quantitative contrast medium uptake and the percentage of contrast medium uptake in the first 2 min are considered. A control MRM during the other half of the cycle may then be indicated and additional diagnostic criteria may improve specificity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050800
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    Paper (German National Licenses)
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