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  • 1
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 108 (1998), S. 2903-2911 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The problem of resonant vibration–vibration (V–V) energy transfer in liquids is explored within a simple model in order to compare two calculational methods. Two bromine diatomics are constrained to move between two fixed argon solvent atoms in one dimension. The time-dependent probability for the transfer of a vibrational excitation between the bromine diatomics is computed semiclassically. The results of single-trajectory molecular dynamics methods are compared with those of multiple-trajectory surface hopping methods. It is found that the two methods give similar results, indicating that the simpler single-trajectory method adequately describes the resonant V to V transfer process. The proximity of the nearly degenerate potential energy surfaces leads to a phase coherence time that exceeds the time required for the transition probability to saturate for this model. As a result, the transition probability remains a nonlinear function of time, and this precludes the extraction of a rate constant from the slope of the resonant V–V transition probability curve for this simple one-dimensional model. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Westerville, Ohio : American Ceramics Society
    Journal of the American Ceramic Society 81 (1998), S. 0 
    ISSN: 1551-2916
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: State-of-the-art infrared (IR) thermal imaging was used to monitor the heating of ZnO varistors by electrical transients. On a macroscopic scale (e.g., 10 mm), heating in large varistor blocks (i.e., diameter of 42 mm) was found to be the greatest near the block edges and to be approximately radially symmetric in blocks fabricated at a low aspect ratio. In blocks fabricated at a higher aspect ratio, the heating was less symmetric, presumably because uniform properties are more difficult to achieve. Nonuniform heating in large blocks can be attributed to processing-induced variations in the electrical properties of the blocks. On an intermediate size scale (e.g., 1 mm), the heating in small varistor disks (e.g., diameter of 10 mm) was observed to be most intense along localized electrical paths. The high electrical conductivity of these paths originates from the statistical fluctuations in properties that inevitably occur in polycrystalline materials. On a microscopic scale (e.g., 10 μm), the heating in thin varistor slices (e.g., thickness of 100 μm) was observed to be localized in strings of tiny hot spots. The hot spots occur at the grain boundaries in a conducting path, where the potential is decreased across Schottky-type barriers and the heat is generated. The experimentally observed heating is interpreted by applying transport theory and using computer simulations. It is shown that, on the scale of the grain size, the heat transfer is too fast to permit temperature differences that could cause a varistor failure. Current localization and nonuniform heating on an intermediate size scale can have a microstructural origin (e.g., statistical fluctuations of grain sizes and grain-boundary properties). However, these are shown to be significant only in small varistors, whereas destructive failures (puncture and cracking) of large varistor blocks can be caused only by nonuniform heating on a macroscopic scale.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd.
    The @journal of popular culture 32 (1998), S. 0 
    ISSN: 1540-5931
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Ethnic Sciences
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Pacing and clinical electrophysiology 21 (1998), S. 0 
    ISSN: 1540-8159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The learning curve characteristics of lead extraction with a laser sheath were examined in 19 patients. Forty-two leads were removed: five leads were removed by traction alone, five required a femoral approach as a primary procedure and a laser sheath was used in 32 lead extraction attempts. Primary laser success was achieved in 26 attempts (81 %). A femoral approach was successfully applied as a back-up procedure in five of the failures. Overall, 26% of the leads were removed by the femoral approach. The overall success rate was 98% (41 of 42 leads). No variables related to the patients, leads, or extraction techniques were significantly related to failure of laser sheath extraction. There was a distinct learning curve with all but one failure occurring in the first half of our cases. All failures occurred with leads implanted from the right subclavian vein. In four, a sharply angled curve at the subclavian vein-superior vena cava junction could not be passed with the laser sheath. The ability to smooth this curve improved the results during the learning curve. All procedures were performed in the operating room for safety reasons. This precaution was lifesaving in a case of acute tamponade after laser extraction of an atrial lead. In another case the left internal mammary artery was torn after laser sheath extraction, causing the formation of a false aneurysm. New pacing leads were introduced in nine patients during the same procedure. The mean procedure time was 255 ± 110 min. reflecting the complexity of these procedures.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK and Boston, USA : Blackwell Publishers Ltd
    Labour 12 (1998), S. 0 
    ISSN: 1467-9914
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: This paper investigates (un)employment dynamics in response to labour demand shocks using a small empirical flow model for the labour market in The Netherlands. The model explicitly takes account of the propagation of shocks through the various duration classes of unemployment and allows for duration dependence in the state of unemployment. A sensitivity analysis shows that 1. congestion in the matching process due to the increase in the pace of job creation and destruction may have substantial effects on (un)employment dynamics; 2. the effects depend very much on the initial pace of labour market dynamics and they are larger when the initial pace is low; 3. the labour market may be out of its equilibrium for quite a long time after a shock occurs; 4. fluctuations in the pace of job creation and destruction only lead to unemployment persistence in the model when the escape probability from long term unemployment is zero; otherwise, the economy returns to its original equilibrium, albeit with long adjustment lags in the case that the initial pace of structural change and/or the escape probability for long term unemployed is low.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Management decision 36 (1998), S. 679-685 
    ISSN: 0025-1747
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: One of the more difficult problems facing academic, business and government institutions is that of evaluating job and/or promotion candidates. A typical evaluation consists of several tasks. First, applications must be gathered. Then, they must be evaluated using a number of criteria such as education, experience, personality, etc. Finally, a weighted average of the various criteria must be developed for each applicant or promotion candidate which represents the individual's overall desirability. Two of the chief difficulties in the above process are: rating individuals for each of the criteria; and developing a logical and consistent set of weights for the various criteria. In this paper we will present Saaty's Analytical Hierarchy Process as a means of dealing with these difficulties. We will also discuss some of the practical problems encountered in applying the method.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0843
    Keywords: Key words Idarubicin ; c-myc ; Breast tumor cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purpose: Studies were designed to elucidate the basis for the antiproliferative activity of the anthracycline antibiotic, idarubicin (4-demethoxy-daunorubicin) in MCF-7 breast tumor cells. Methods: Growth inhibition was evaluated using the MTT tetrazolium dye assay, induction of DNA strand breaks was determined by alkaline elution, inhibition of DNA synthesis was assessed by measuring the incorporation of labelled thymidine into DNA, modulation of the expression of the c-myc oncogene was determined by Northern blotting and the induction of apoptosis was evaluated by alkaline unwinding, static field gel electrophoresis, terminal end labelling and assessment of cell morphology. Results: MCF-7 cells were relatively sensitive to idarubicin, with an IC 50 value for growth inhibition of approximately 0.01 μM. While DNA strand breakage was not evident below a concentration of 0.1 μM idarubicin, where growth inhibition exceeded 70%, both the inhibition of DNA synthesis and suppression of c-myc expression closely paralleled the profile of antiproliferative activity for idarubicin. Finally, while exposure to idarubicin resulted in a substantial loss of viable cells within 48–72 h, there was no morphological evidence of apoptotic body formation. The absence of apoptosis in cells exposed to idarubicin was supported by studies demonstrating the absence of DNA fragmentation using gel electrophoresis, alkaline elution and in situ DNA end-labelling assays. Conclusions: The results of these studies extend previous results from this laboratory indicating an association between suppression of c-myc expression, inhibition of DNA synthesis and growth arrest by topoisomerase II inhibitors, as well as the lack of induction of apoptotic cell death by topoisomerase II inhibitors in MCF-7 breast tumor cells.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of experimental and theoretical physics 87 (1998), S. 655-662 
    ISSN: 1090-6509
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The possibilities of current-sheet formation in two-dimensional magnetic fields with a null line as well as the characteristic features of the plasma dynamics under high initial pressure conditions (helium, P 0≈300 mtorr) are investigated for the first time. It is shown that current-sheet formation and efficient compression of the plasma into a sheet require that the magnetic field gradient be sufficiently large. A brightly emitting compact region with electron density N e∼9×1016 cm−3, an order of magnitude higher than the gas atom density, was observed to form at the center of the layer.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1090-6487
    Keywords: 28.20.Cz ; 11.55.Fv
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract An experiment to check the standard dispersion law for ultracold neutrons is described. The experiment is based on searching for a shift of the resonance line of a neutron interference filter as the neutron velocity component parallel to the filter surface is varied. The first results attest to a statistically significant effect. No mimicking effects were found in a control experiment, but their possible existence cannot be completely ruled out at present.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Annals of surgical oncology 5 (1998), S. 751-756 
    ISSN: 1534-4681
    Keywords: Juvenile polyposis ; Gastrointestinal carcinoma ; Colorectal cancer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Familial juvenile polyposis (JP) is an autosomal dominant condition in which affected individuals develop upper or lower gastrointestinal (GI) juvenile polyps, or both, and have a predisposition to cancer of the gastrointestinal tract. The risk of GI cancer has not been well defined because of the small number of these families and the lack of follow-up. The objective of this study was to determine the prevalence and age at diagnosis of GI polyposis and cancer in a large JP kindred. Methods: Medical records were reviewed, patients were interviewed, and histories were taken. Pathology reports and slides were reviewed by our pathologists. A database was created for analysis of clinical and pathologic factors. Results: This kindred contains 117 members, 29 of whom have had upper or lower GI polyps or cancer, or both. All those affected have had colonic juvenile polyps or cancer, except for two who died of advanced gastric cancer and never had colonic evaluation. Nine individuals have had both upper and lower GI polyps or cancer. Sixteen of 29 (55%) affected patients have developed gastrointestinal cancer. Eleven (38%) have had colon cancer, and six (21%) have had upper GI cancers. Conclusions: The risk of gastrointestinal malignancy in affected members of this JP kindred exceeds 50%. The high risk of GI cancer warrants frequent endoscopic screening of both affected and at-risk family members. Screening will soon be facilitated by presymptomatic genetic testing for the identification of gene carriers.
    Type of Medium: Electronic Resource
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