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  • 2015-2019  (3)
  • 2000-2004  (293)
  • 1925-1929  (57)
  • 1850-1859  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    The effects of fungal inoculum arrangement (scale and context) on emergent community development in an agar model system (2002)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology ecology 39 (2002), S. 0 
    Details
    ISSN: 1574-6941
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Consequences of initial spatial organisation of model fungal communities upon their spatio-temporal development were investigated. Dynamics of prescribed two- and three-species ‘communities’ developing on tessellated agar tile model systems were analysed in terms of literal maps, principal component analyses, or as the proportion of species extant within tiles. It was established that for two-species interactions of equal patch size, large-scale (i.e. many constituent tiles) behaviour could be extrapolated from the relevant small-scale (i.e. pairs of tiles) interactions. However, relative patch sizes (scale) of species within tessellations influenced the times taken by individuals to colonise tiles and, hence, temporal behaviour of the system. Outcome of arrangements involving three species of equal patch size and inoculum potential, and prescribed with different mixing patterns, could not be directly extrapolated by reference to the outcome of pair-wise interactions between constituent species. Three-species arrangements attempt to limit assembly of lateral aggregates of individuals (patch size) and hence any effects of tile colonisation times, so as to reveal effects of nearest neighbour context within the complex community. Such arrangements indicate that spatial configuration of inoculum influences community development and reproducibility. They also suggest that spatial distribution of species affects persistence of individuals, which would otherwise be expected to be eliminated from the system. Two-species interactions appeared generally more reproducible than those comprising three species, and the sensitivity of fungal community development to temperature was not solely associated with influence on colony extension rate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6941.2002.tb00901.x
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    The five Ss of retail operations: a model and tool for improvement (2003)
    Bingley : Emerald
    International journal of retail and distribution management 31 (2003), S. 518-528 
    Details
    ISSN: 0959-0552
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Reviews the academic and practitioner literature on retail operations and identifies five core elements of retail operations. Proposes a method by which managers can examine ways of improving their operations by the use of a modified cause-effect technique. Provides worked examples of the technique.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/09590550310497049
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    Paper (German National Licenses)
    Fulltext
  • 3
    Book
    Book
    Building high integrity applications with SPARK / (2015)
    New York, NY :Cambridge University Press,
    Details
    Title: Building high integrity applications with SPARK /
    Author: McCormick, John W.
    Contributer: Chapin, Peter C.
    Publisher: New York, NY :Cambridge University Press,
    Year of publication: 2015
    Pages: XIV, 367 S.
    ISBN: 978-1-107-04073-1 , 978-1-107-65684-0
    Type of Medium: Book
    Language: English
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    ZIB Catalog
    Zuse Institute Berlin get availability status
  • 4
    facet.materialart.
    Unknown
    The role of titanium surface nanotopography on preosteoblast morphology, adhesion and migration (2017)
    Details
    Publication Date: 2022-07-19
    Description: Surface structuring of titanium-based implants with appropriate nanotopographies can significantly modulate their impact on the biological behavior of cells populating these implants. Implant assisted bone tissue repair and regeneration require functional adhesion and expansion of bone progenitors. The surface nanotopography of implant materials used to support bone healing and its effect on cell behavior, in particular cell adhesion, spreading, expansion, and motility, is still not clearly understood. The aim of this study is to investigate preosteoblast proliferation, adhesion, morphology, and migration on different titanium materials with similar surface chemistry, but distinct nanotopographical features. Sonochemical treatment and anodic oxidation were employed to fabricate disordered – mesoporous titania (TMS), and ordered – titania nanotubular (TNT) topographies respectively. The morphological evaluation revealed a surface dependent shape, thickness, and spreading of cells owing to different adherence behavior. Cells were polygonal-shaped and well-spread on glass and TMS, but displayed an elongated fibroblast-like morphology on TNT surfaces. The cells on glass however, were much flatter than on nanostructured surfaces. Both nanostructured surfaces impaired cell adhesion, but TMS was more favorable for cell growth due to its support of cell attachment and spreading in contrast to TNT. Quantitative wound healing assay in combination with live-cell imaging revealed that cells seeded on TMS surfaces migrated in close proximity to neighboring cells and less directed when compared to the migratory behavior on other surfaces. The results indicate distinctly different cell adhesion and migration on ordered and disordered titania nanotopographies, providing important information that could be used in optimizing titanium-based scaffold design to foster bone tissue growth and repair.
    Language: English
    Type: article , doc-type:article
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    OPUS
  • 5
    facet.materialart.
    Unknown
    The role of titanium surface nanotopography on preosteoblast morphology, adhesion and migration (2017)
    Details
    Publication Date: 2022-07-19
    Description: Surface structuring of titanium-based implants with appropriate nanotopographies can significantly modulate their impact on the biological behavior of cells populating these implants. Implant assisted bone tissue repair and regeneration require functional adhesion and expansion of bone progenitors. The surface nanotopography of implant materials used to support bone healing and its effect on cell behavior, in particular cell adhesion, spreading, expansion, and motility, is still not clearly understood. The aim of this study is to investigate preosteoblast proliferation, adhesion, morphology, and migration on different titanium materials with similar surface chemistry, but distinct nanotopographical features. Sonochemical treatment and anodic oxidation were employed to fabricate disordered – mesoporous titania (TMS), and ordered – titania nanotubular (TNT) topographies respectively. The morphological evaluation revealed a surface dependent shape, thickness, and spreading of cells owing to different adherence behavior. Cells were polygonal-shaped and well-spread on glass and TMS, but displayed an elongated fibroblast-like morphology on TNT surfaces. The cells on glass however, were much flatter than on nanostructured surfaces. Both nanostructured surfaces impaired cell adhesion, but TMS was more favorable for cell growth due to its support of cell attachment and spreading in contrast to TNT. Quantitative wound healing assay in combination with live-cell imaging revealed that cells seeded on TMS surfaces migrated in close proximity to neighboring cells and less directed when compared to the migratory behavior on other surfaces. The results indicate distinctly different cell adhesion and migration on ordered and disordered titania nanotopographies, providing important information that could be used in optimizing titanium-based scaffold design to foster bone tissue growth and repair.
    Language: English
    Type: reportzib , doc-type:preprint
    Format: application/pdf
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    OPUS
  • 6
    Unknown
    Urban drainage (2004)
    London ; New York : Spon Press
    Details
    Keywords: Urban runoff.
    Pages: xxii, 543 p.
    Edition: 2nd ed
    ISBN: 0-203-14969-6
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=116885
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    E-Book (German National Licenses)
  • 7
    Electronic Resource
    Electronic Resource
    Structure and dynamics of N2–IH (2000)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 113 (2000), S. 249-257 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The ground state rotational spectra and internal dynamics in five isotopomers 14N2–IH, 14N2–ID, 15N2–IH, 14N15N–IH, and 15N14N–IH of the nitrogen–hydrogen iodine dimer have been investigated by pulsed-nozzle, Fourier-transform microwave spectroscopy. Analysis of the recorded spectra yields rotational, centrifugal distortion, nuclear quadrupole and spin-rotation coupling constants for the five isotopomers. The spectroscopic constants are interpreted in terms of a ground-state NN–IH structure using the parameters rcm, kσ, and the oscillation angles θN2 and θHI of the N2 and IH moieties. For 14N2–IH, the values rcm=4.197 872(67) Å, kσ=1.461 52(32) N/m, θN2=25.61(22)°, and θHI=23.454 6(91)° are obtained. The rotational transitions of 14N2–IH, 14N2–ID, and 15N2–IH show a doubling, which is a consequence of tunneling associated with the interchange of the two nitrogen nuclei. The experimental findings are compared with results from ab initio calculations. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.481791
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    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    The effects of funding source and management ownership on the productivity of R&D (2004)
    Oxford, UK : Blackwell Publishing
    R & D management 34 (2004), S. 0 
    Details
    ISSN: 1467-9310
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: This study investigates the influence of the source of R&D funds and management ownership on R&D productivity. The lagged effect of the source of R&D funds on R&D output is investigated for a sample of US manufacturing firms in five industries over the 1996–99 period. Estimates based on 779 firm-years show that R&D productivity increases with the proportion of stock held by managers and directors of firms primarily in the Other Electronics industry. The estimates also show that recipients of government-sponsored R&D funds in the Chemicals industry have lower levels of output (sales) for each dollar committed to R&D. In addition, output for firms in the Chemicals industry worsens as management stockholding increases, implying an agency cost rationale for the observed difference in output. The implication is that firms with high manager-owner content are less productive with government-sponsored R&D than with company-financed R&D. The reported results suggest that potential agency costs should be incorporated in government-sponsored R&D contracts. It also suggests that the source of R&D funds should be disclosed and incorporated into the valuation of intangible assets attributable to research and development.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1467-9310.2004.00339.x
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    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    POXVIRUSES AND IMMUNE EVASION (2003)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Immunology 21 (2003), S. 377-423 
    Details
    ISSN: 0732-0582
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology , Medicine
    Notes: Abstract Large DNA viruses defend against hostile assault executed by the host immune system by producing an array of gene products that systematically sabotage key components of the inflammatory response. Poxviruses target many of the primary mediators of innate immunity including interferons, tumor necrosis factors, interleukins, complement, and chemokines. Poxviruses also manipulate a variety of intracellular signal transduction pathways such as the apoptotic response. Many of the poxvirus genes that disrupt these pathways have been hijacked directly from the host immune system, while others have demonstrated no clear resemblance to any known host genes. Nonetheless, the immunological targets and the diversity of strategies used by poxviruses to disrupt these host pathways have provided important insights into diverse aspects of immunology, virology, and inflammation. Furthermore, because of their anti-inflammatory nature, many of these poxvirus proteins hold promise as potential therapeutic agents for acute or chronic inflammatory conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.immunol.21.120601.141049
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Technology Trends in Staffing and Assessment: A Practice Note (2003)
    Oxford, UK : Blackwell Publishing
    International journal of selection and assessment 11 (2003), S. 0 
    Details
    ISSN: 1468-2389
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: This practice note listed and described, from a practitioner's perspective, ten dominant technology trends that are impacting the personnel testing industry. Five trends were classified as ‘platform-centric,’ and five were classified as ‘information-centric.’ Platform-centric trends were related to virtual career centers, integrated assessment platforms, media-rich assessments, technology-friendly tests, and the adaptation of personnel tests to emerging technologies. Information-centric trends were related to Internet-age access and fairness concerns, computer-enabled scoring innovations, strategic HR data warehousing and mining, satisfaction with computer-based assessments, and computer-based testing standards. A review of these ten technology trends suggests that the personnel testing industry is keeping pace with rapid technological innovations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/1468-2389.00248
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    Paper (German National Licenses)
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