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  • 2005-2009
  • 2000-2004
  • 1995-1999  (4)
  • Civil and Mechanical Engineering  (2)
  • 2,4,6-trinitrotoluene  (1)
  • 2-butanediol)-3′-nitrotyramine  (1)
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Years
  • 2005-2009
  • 2000-2004
  • 1995-1999  (4)
Year
  • 1
    ISSN: 1432-0738
    Keywords: Key words N-nitroso-N-(3-keto-1 ; 2-butanediol)-3′-nitrotyramine ; Unschedule DNA synthesis ; Genotoxicity ; Initiating agent
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract   N-Nitroso-N-(3-keto-1,2-butanediol)-3′-nitrotyramine (NO-NTA) is a product of a model browning system in the presence of sodium nitrite. In this study, the chemical structure is confirmed by spectral studies, including UV, mass spectrometry, nuclear magnetic resonance and infrared spectroscopy. NO-NTA is strongly genotoxic to the rat hepatocyte and is moderately cytotoxic to mouse C3H10T1/2 cells. Results obtained in this study indicate that NO-NTA inflicted DNA damage through the formation of a DNA adduct. In addition, C3H10T1/2 cells were treated with NO-NTA and, following addition of 12-O-tetradecanoylphorbol-13-acetate (TPA) as promotor, the increase of transformed foci indicated that NO-NTA could possibly be an inhibitor of TPA tumor promotion. A transformed cell line from NO-NTA initiated and TPA promoted foci increased saturation density and growth ability in soft agar reactive to the control line. These results suggest that the formation of a genotoxic agent of nitroso-derivatives may take place in a nitrite-containing food system during processing and cooking.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Biotechnology techniques 12 (1998), S. 839-842 
    ISSN: 1573-6784
    Keywords: 2,4,6-trinitrotoluene ; 2,4,6-triaminotoluene ; derivatization ; separation ; HPLC
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract 2,4,6-Triaminotoluene (TAT), an oxygen sensitive metabolic product of 2,4,6-trinitrotoluene (TNT) reduction, was derivatized yielding oxygen stable products using a procedure previously employed for the stabilization of other O2sensitive TNT metabolic products. A HPLC method is presented that allows for the separation of diverse intermediates and products of TNT metabolism following the derivatization procedure. © Rapid Science Ltd. 1998
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 22 (1998), S. 425-447 
    ISSN: 0363-9061
    Keywords: closed-form solution ; transversely isotropic half-space ; Fourier transform ; Hankel transform ; rock anisotropy ; Engineering ; Civil and Mechanical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: We rederive and present the complete closed-form solutions of the displacements and stresses subjected to a point load in a transversely isotropic elastic half-space. The half-space is bounded by a horizontal surface, and the plane of transverse isotropy of the medium is parallel to the horizontal surface. The solutions are obtained by superposing the solutions of two infinite spaces, one acting a point load in its interior and the other being free loading. The Fourier and Hankel transforms in a cylindrical co-ordinate system are employed for deriving the analytical solutions. These solutions are identical with the Mindlin and Boussinesq solutions if the half-space is homogeneous, linear elastic, and isotropic. Also, the Lekhnitskii solution for a transversely isotropic half-space subjected to a vertical point load on its horizontal surface is one of these solutions. Furthermore, an illustrative example is given to show the effect of degree of rock anisotropy on the vertical surface displacement and vertical stress that are induced by a single vertical concentrated force acting on the surface. The results indicate that the displacement and stress accounted for rock anisotropy are quite different for the displacement and stress calculated from isotropic solutions. © 1998 John Wiley & Sons, Ltd.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 22 (1998), S. 495-508 
    ISSN: 0363-9061
    Keywords: consolidation ; cohesive soil ; clay ; axial strain ; true triaxial ; finite difference method ; Engineering ; Civil and Mechanical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: This paper presents a simplified approach for the analysis of axial strain induced by three-dimensional consolidation of cohesive soils. The axial strain is divided into a constant volume component and a consolidation component. A relevant undrained stress-strain relationship is required to determine the constant volume component. A theoretical formulation is developed for the evaluation of the consolidation component. Predictions of the axial strain accompanying true triaxial laboratory tests for a variety of stress patterns correlate sufficiently well with the measured data. The proposed method is potentially applicable in conjunction with a finite difference scheme to analyze the time-dependent response of pile groups subjected to static vertical loading. © 1998 John Wiley & Sons, Ltd.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
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