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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Experiments in fluids 25 (1998), S. 283-297 
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  The Reynolds-averaged flow for a solid/free-surface juncture boundary layer and wake is documented. The three mean-velocity components and five of the Reynolds stresses are measured for a surface-piercing flat plate in a towing tank using a laser-Doppler velocimeter system for both boundary-layer and wake planes in regions close to the free surface. The experimental method is described, including the foil-plate model, laser-Doppler velocimeter system, conditions, and uncertainty analysis. The underlying flow data is in excellent agreement with benchmark data. Inner (near the plate and wake centerplane and below the free surface) and outer (near the free surface) regions of high streamwise vorticity of opposite sign are observed, which transport, respectively, high mean velocity and low turbulence from the outer to the inner and low mean velocity and high turbulence from the inner to the outer portions of the boundary layer and wake. For the wake, the inner region of vorticity is relatively weak. The physical mechanism for the streamwise vorticity is analyzed with regard to the Reynolds-averaged streamwise vorticity equation. The anisotropy of the crossplane normal Reynolds stresses closely correlates with the vorticity and, additionally, indicates similarity, i.e., its nature is such that it only depends on the proximity to the plate and free surface boundaries or wake centerplane symmetry plane. Free-surface effects on the Reynolds stresses are analyzed with regard to the behavior close to the free surface of the turbulent kinetic energy and the normal components of the anisotropy tensor and the anisotropy invariants. Close to the free surface, the turbulent kinetic energy is nearly constant and increases for the inner and outer portions, respectively, of the boundary layer and wake and the normal components of the anisotropy tensor and the anisotropy invariants roughly correspond to the limiting values for two-component turbulence. The similarities and differences between the present results and analysis with those from related studies are discussed. The data and analysis should have practical application with regard to the development of turbulence models for computational fluid dynamics methods for the Reynolds-averaged Navier–Stokes equations.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0738
    Keywords: Key words N-nitroso-N-(3-keto-1 ; 2-butanediol)-3′-nitrotyramine ; Unschedule DNA synthesis ; Genotoxicity ; Initiating agent
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract   N-Nitroso-N-(3-keto-1,2-butanediol)-3′-nitrotyramine (NO-NTA) is a product of a model browning system in the presence of sodium nitrite. In this study, the chemical structure is confirmed by spectral studies, including UV, mass spectrometry, nuclear magnetic resonance and infrared spectroscopy. NO-NTA is strongly genotoxic to the rat hepatocyte and is moderately cytotoxic to mouse C3H10T1/2 cells. Results obtained in this study indicate that NO-NTA inflicted DNA damage through the formation of a DNA adduct. In addition, C3H10T1/2 cells were treated with NO-NTA and, following addition of 12-O-tetradecanoylphorbol-13-acetate (TPA) as promotor, the increase of transformed foci indicated that NO-NTA could possibly be an inhibitor of TPA tumor promotion. A transformed cell line from NO-NTA initiated and TPA promoted foci increased saturation density and growth ability in soft agar reactive to the control line. These results suggest that the formation of a genotoxic agent of nitroso-derivatives may take place in a nitrite-containing food system during processing and cooking.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Chromatography A 519 (1990), S. 137-143 
    ISSN: 0021-9673
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0032-0633
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Geosciences , Physics
    Type of Medium: Electronic Resource
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