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  • 1
    Electronic Resource
    Electronic Resource
    Boss Forming, An Environment-Friendly Rotary Forming (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 344 (July 2007), p. 947-953 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Boss forming, which is sometimes called hub forming, has attracted its attention as anenvironment-friendly rotary forming process to form a circular plate with a hole into a boss shape.An experimental study was conducted to survey the technological possibility of boss forming. Bossforming of A1050-O commercially pure aluminum plate of 10 mm thickness was carried out atroom temperature under various working conditions. The effects of the working conditions on themetal flow in boss forming were clarified experimentally
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/54/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.344.947.pdf
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Lymphocyte Subsets in Lung Tissues of Non-specific Interstitial Pneumonia and Pulmonary Fibrosis Associated with Collagen Vascular Disorders: Correlation with CD4/CD8 Ratio in Bronchoalveolar Lavage (2000)
    Springer
    Lung 178 (2000), S. 361-370 
    Details
    ISSN: 1432-1750
    Keywords: Key words: Lymphocytes—Subset—CD4—CD8—Bronchoalveolar lavage—Open lung biopsy.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. This study was designed to evaluate the distribution of lymphocyte subsets in lung specimens that were obtained by open-lung biopsy from 8 patients with idiopathic nonspecific interstitial pneumonia/fibrosis (NSIP) and 10 patients with pulmonary fibrosis associated with collagen vascular disorders (PF-CVD). Distributions of B lymphocytes, CD4-positive T lymphocytes, and CD8-positive T lymphocytes were evaluated immunohistochemically and compared with the cell composition in BALF. Correlation between CD4/CD8 ratios in bronchoalveolar lavage fluids (BALF) and CD4/CD8 ratios in lung tissues was also examined. B lymphocytes were mostly restricted in lymphoid follicles. CD4-positive T lymphocytes were observed inside and around lymphoid follicles and in the thick fibrotic wall of reconstructed alveoli with fibrosis. In contrast, CD8-positive T lymphocytes were diffusely distributed, especially in relatively thin alveoli. Correlation was weak between CD4/CD8 ratios in lung tissue and CD4/CD8 ratios in BALF. However, even in patients with very low CD4/CD8 ratios in BALF, many CD4 lymphocytes were observed in lung tissues, suggesting that CD8-positive lymphocytes diffusely distributed in thin alveolar architecture were more easily recovered in BALF than CD4-positive lymphocytes. Therefore, a low CD4/CD8 ratio in BALF may indicate that the alveolar structure was not severely reconstructed by fibrosis. This is the first report that compared lymphocyte subsets in lung tissues and in BALF.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004080000037
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Elevation of Anti-Cytokeratin 18 Antibody and Circulating Cytokeratin 18: Anti-Cytokeratin 18 Antibody Immune Complexes in Sera of Patients with Idiopathic Pulmonary Fibrosis (2000)
    Springer
    Lung 178 (2000), S. 171-179 
    Details
    ISSN: 1432-1750
    Keywords: Key words: Autoantibody—Cytokeratin 18—Idiopathic pulmonary fibrosis—Immune complexes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. In this study, we hypothesize that anti-cytokeratin 18 (CK18) antibody and CK18:anti-CK18 immune complex increase in sera in patients with idiopathic pulmonary fibrosis (IPF). To prove the existence of anti-CK18 antibodies in patients' sera, bovine CK18 was stained with patients' sera using a Western blotting. In patients with IPF, anti-CK18 antibodies were clearly demonstrated in sera by Western blotting. Then, we tried to establish an enzyme-linked immunosorbent assay (ELISA) to quantify anti-CK18 antibodies and CK18:anti-CK18 immune complexes in sera of patients with IPF. Levels of anti-human CK18 antibodies in sera of patients with IPF (0.81 ± 0.31, mean ± SD) measured by ELISA were significantly high compared with that of normal volunteers (0.45 ± 0.06, p 〈 0.01). In addition, levels of CK18:anti-CK18 antibody complexes in patients' sera (0.64 ± 0.35, man ± SD) significantly increased compared with those of normal subjects (0.40 ± 0.10, p 〈 0.01). These results suggest that anti-CK18 antibody and its immune complex may have played a role in the process of lung injury in IPF.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004080000020
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    Paper (German National Licenses)
    Fulltext
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