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  • 11
    Electronic Resource
    Electronic Resource
    Review article: the management of primary sclerosing cholangitis (1997)
    Oxford BSL : Blackwell Science
    Alimentary pharmacology & therapeutics 11 (1997), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by a progressive obliterating fibrosis of the intrahepatic and extrahepatic bile ducts. The pathogenesis of PSC is poorly understood but it is thought to be an immune-mediated disease. The optimal therapy which successfully improves symptoms, delays progression towards liver failure and transplantation and prevents the onset of cholangiocarcinoma remains elusive. Although current treatments are used to manage cholestasis and its consequences and some of the more general complications of the disease, none of the current therapeutic agents have been shown to retard and reverse the rate of disease progression. The role of cupruretics, corticosteroids, methotrexate, anti-fibrogenic agents and ursodeoxycholic acid in the treatment of PSC is reviewed. Orthotopic liver transplantation remains the only therapeutic option for advanced PSC but the timing of transplantation remains controversial and the possibility of recurrence of the disease in the graft is increasingly recognised. It is likely that greater insight into the pathogenetic mechanisms involved in PSC will allow therapy to be targetted more specifically at the biliary epithelium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.1997.91263000.x
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  • 12
    Electronic Resource
    Electronic Resource
    A photometric redshift of z = 6.39 ± 0.12 for GRB 050904 (2006)
    [s.l.] : Nature Publishing Group
    Nature 440 (2006), S. 181-183 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Gamma-ray bursts (GRBs) and their afterglows are the most brilliant transient events in the Universe. Both the bursts themselves and their afterglows have been predicted to be visible out to redshifts of z ≈ 20, and therefore to be powerful probes of the early Universe. The burst GRB 000131, ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature04552
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  • 13
    Electronic Resource
    Electronic Resource
    An origin in the local Universe for some short γ-ray bursts (2005)
    [s.l.] : Nature Publishing Group
    Nature 438 (2005), S. 991-993 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Gamma-ray bursts (GRBs) divide into two classes: ‘long’, which typically have initial durations of T90 〉 2 s, and ‘short’, with durations of T90 〈 2 s (where T90 is the time to detect 90% of the observed fluence). Long ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature04310
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  • 14
    Electronic Resource
    Electronic Resource
    Demonstration of Strain-hardening of Steel (1915)
    [s.l.] : Nature Publishing Group
    Nature 94 (1915), S. 589-589 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE accompanying photograph (Fig. 1) represents the side of a steel bar. The bar was first marked by a punch in the way shown, and the punch marks were afterwards completely filed out. The side was then polished and the bar pulled in a testing machine beyond the elastic limit of the material. ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/094589c0
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  • 15
    Electronic Resource
    Electronic Resource
    Gamma-spectroscopy of the 199At nucleus with the Recoil Filter Detector (1998)
    Springer
    The European physical journal 3 (1998), S. 311-312 
    Details
    ISSN: 1434-601X
    Keywords: PACS:23.20.Lv Gamma transitions and level energies – 27.80.+w 190 ≤ A ≤ 219 – 29.40.Ym Other detectors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. The neutron deficient 199At nucleus has been studied in the 175Lu+28Si reaction at Eb= 141 MeV. In order to select events of interest in the presence of the very strong background caused by fission, γ-rays have been detected in coincidence with recoiling evaporation residues. The excited states of 199At observed for the first time may indicate that this nucleus is deformed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100500050184
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  • 16
    Electronic Resource
    Electronic Resource
    The observation of a superdeformed structure in82Y (1995)
    Springer
    The European physical journal 353 (1995), S. 251-253 
    Details
    ISSN: 1434-601X
    Keywords: 21.10.Re ; 21.60.Cs ; 23.20.Lv ; 27.50.+e
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The58Ni(30Si,αpn)82Y reaction at a beam energy of 134 MeV was used to populate the odd-odd nucleus82Y and coincidentγ rays depopulating high spin states in the evaporation residues were detected with the EUROGAM Phase 2 array. A superdeformed structure has been observed with an intensity of 1.5±0.5%. The cascade of 9 coincidentγ rays has consecutive energy spacing of ∼160 keV. This corresponds to a dynamic moment of inertia which is almost constant at approx mately 25h 2 MeV−1. The band is interpreted as a signature=0, negative parity SD band with aπ51 V52 intrinsic intruder configuration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01292329
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  • 17
    Electronic Resource
    Electronic Resource
    Rotational bands in 167Hf (1999)
    Springer
    The European physical journal 6 (1999), S. 37-42 
    Details
    ISSN: 1434-601X
    Keywords: PACS: 23.20.Lv Gamma transitions and level energies – 27.70.+q 150 〈 A 〈 189
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: High-spin states in 167Hf, populated in the 141Pr(30Si, p3n)167Hf reaction, have been studied using the nordball Ge detector array. Three rotational cascades have been observed for the first time and the previously-known level scheme has been extended to significantly higher spin. Band-crossing effects are discussed within the framework of Woods-Saxon cranking calculations and are found to be in good agreement.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100500050314
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  • 18
    Electronic Resource
    Electronic Resource
    The Al (Nb, Ta) Ti(in−2) substitution in titanite: the emergence of a new species? (1995)
    Springer
    Mineralogy and petrology 52 (1995), S. 61-73 
    Details
    ISSN: 1438-1168
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Zusammenfassung Die AI(Nb, Ta)Ti−2 Substitution im Titanit: Auftauchen einer neuen Mineralspecies? Die höchsten (Nb, Ta) Gehalte, die jemals für Titanit gefunden wurden, werden für den Maršíkov II Pegmatit in Nordmähren, Tschechei, berichtet. Der Intrusivgang ist Teil eines Amphibolit-faziell überprägten Pegmatitschwarms vom Beryll-Columbit Subtypus Der Pegmatit führt u.a. seltene tantalbetonte Rutile verwachsen mit titanbetontem Ixiolith, titanbetontem Columbit-Tantalit, Fersmit and Mikrolith. Deformationsbedingte Frakturen in den (Nb, Ta) Oxiden sind mit Titanit, als Folge der Reaktion der metamorphen Porenlösungen mit den Oxidmineralen, verkittet. Titanit zeigt begrenzte Substitutionen Na(Ta 〉 Nb)(CaTi)−1,(Ta 〉 Nb)4□Ti−4Si−1 and Al(OH, F)(TiO)−1, aber extensive (und gelegentlich einzig bedeutsame) Substitution (Al 〉〉 Fe3+)(Ta 〉 Nb)Ti−2, die eine weitverbreitete, oszillierende Zonierung hervorruft. Diese Substitution verringert den Anteil der Titanit-Komponentesensu stricto, CaTiSiO,O, auf weniger als 50 Mol% in vielen Analysen. Die Extremzusammensetzung entspricht Ca0.994Na0.11) (T10.436Sn0.007Al0.280Fe3+ 0.006Ta0.199Nb0.079)Si0.988O4(O0.974F0.026). Das AusmaB dieser Substitution ist unzureichend, um eine neue Mineralspecies zu definieren.
    Notes: Summary The highest (Nb, Ta) content ever encountered in titanite is reported from the Maršíkov 11 pegmatite in northern Moravia, Czech Republic. This dike is a member of a pegmatite swarm of the beryl-columbite subtype, metamorphosed under conditions of the amphibolite facies. The pegmatite carries, i.a., rare tantalian rutile intergrown with titanian ixiolite, titanian columbite-tantalite, fersmite and microlite. Fissures generated in the Nb, Ta oxide minerals during deformation are filled with titanite, formed by reaction of the oxide minerals with metamorphic pore fluids. The titanite displays limited degrees of substitutions Na(Ta 〉 Nb)(CaTi)−1, (Ta 〉 Nb)4□Ti−4Si−1 and AI(OH, F)(TiO)−1, but an extensive (and occasionally the sole significant) substitution (Al 〉 Fe3+)(Ta 〉 Nb)Ti−2, responsible for widespread oscillatory zoning. This substitution reduces the proportion of the titanite componentsensu stricto, CaTiSiO4,O, to less than 50 mole % in many analyzed spots. The extreme composition corresponds to (Ca0.994Na0.011)(Ti0.436Sn0.007Al0.280Fe3+ 0.006Ta0.199Nb0.079)Si0.988O4(O0.974F0.026). However, so far this substitution fails to generate compositions that would define a new species.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01163126
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  • 19
    Electronic Resource
    Electronic Resource
    Geochemical and structural evolution of micas in the Rožná and Dobrá Voda pegmatites, Czech Republic (1995)
    Springer
    Mineralogy and petrology 55 (1995), S. 177-201 
    Details
    ISSN: 1438-1168
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Zusammenfassung In 11 bis 60 Proben von Biotit, Muskovit und Lepidolith aus den Pegmatiten von Rožná (Typlokalität des Lepidoliths; 323 ± 9 Ma) in Westmähren wurden Chemie, Struktur-parameter, Polytypie, optische Eigenschaften und Rb-Sr-Isotopie untersucht. An beiden Lokalitäten wird früher Biotit an Endokontakten nach Innen von Muskovit und Lepidolith gefolgt, letzterer ist in und um den Kern konzentriert. In Rožná folgt 1M-Lepidolith auf 2M1-Muskovit, aber alle späteren Lepidolithgenerationen sind 2M2, nahe Tri50Ply50 und zum Teil mit 2M1-Muskovit vergesellschaftet. In Dobrá Voda sind alle Lepidolithe vom Typ 1M und frei von Muskovit, die späten Varietäten kommen Tri50Ply50 nahe. An beiden Lokalitäten ist während des Fortschreitens der Glimmerkristallisation eine Tendenz von steigendem μHF angezeigt, die in der Ausfällung von Topas ihren Höhepunkt findet. Die Polytypie des Lepidoliths kann nicht mit irgendeiner Eigenheit der Zusammensetzung oder des Wachstums korreliert worden, auch nicht mit einer Kombination von diesen. Während der ganzen Glimmerkristallisation nimmt Rb/Cs ab, aber die Tendenz von K/Rb ändert sich nach anfänglichem Abfall. Das Bor verteilt sich bevorzugt auf den Muskovit (bis zu 1.10 Gew. -% B2O3), aber die Be-, Zn-, Mn- und Sc-Gehalte sind im Lepidolith erhöht. Ein leichter Ansteig von Fe, Ba und Cl in der letzten Lepidolithgeneration könnte vielleicht durch eine Mischung von pegmatitischen Restlösungen mit metamorphen Porenlösungen verursacht sein.
    Notes: Summary The chemistry, structural parameters, polytypism, optical properties and Rb-Sr isotopes were examined in 11 to 60 samples of biotite, muscovite and lepidolite from the pegmatites at Rožná (the type locality of lepidolite; 323 ± 4Ma) and Dobrá Voda (306 ± 9Ma) in western Moravia. At both localities, early endocontact biotite is followed inwards by muscovite and lepidolite, which is concentrated in and around the core. At Rožná, a 1M lepidolite follows after 2M1 muscovite but all later generations of lepidolite are 2M2, close to Tri50 Ply50 and in part associated with muscovite 2M1. At Dobrá Voda, all lepidolite types are 1M and free of muscovite, and the late varieties approximate Tri30 Ply70. At both localities, a trend of increasing μHF is indicated during the progress of mica crystallization, culminating in precipitation of topaz. Polytypism of lepidolite is not correlatable with any compositional or growth feature, or their combination. Throughout the mica crystallization, Rb/Cs decreases but K/Rb becomes reversed after an initial decrease. Boron is partitioned preferentially into muscovite (up to 1.10 wt.% B2O3) but Be, Zn, Mn and Sc are enhanced in lepidolite. A slight increase in Fe, Ba and Cl in the last generation of lepidolite might be possibly due to mixing of residual pegmatite fluids with metamorphic pore solutions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01162587
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  • 20
    Electronic Resource
    Electronic Resource
    Phenotypic plasticity in numbers of antennal chemoreceptors in a grasshopper: effects of food (1998)
    Springer
    Journal of comparative physiology 183 (1998), S. 69-76 
    Details
    ISSN: 1432-1351
    Keywords: Key words Phenotypic plasticity ; Chemoreceptors ; Antenna ; Grasshopper ; Salicin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Grasshoppers, Schistocerca americana, reared from hatching on artificial diet had fewer sensilla on the antennae in the final larval stage than insects reared on lettuce. This was true of basiconic and coeloconic sensilla (presumed olfactory) and trichoid sensilla (presumed gustatory). The degree of difference varied along the antenna and with sensillum type. Adding salicin to the diet restored the numbers of all types of sensillum to levels equal to, or approaching, those in lettuce-fed insects. The addition of some volatile compounds – carvone (monoterpene), chalcone (flavonoid), citral (monoterpene) and guaiacol (phenolic) – resulted in slight increases in number, but coumarin (phenylpropanoid) had no effect. None of the compounds, either singly or in combination, produced more sensilla than were present in plant-fed insects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003590050235
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