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  • 1
    Electronic Resource
    Electronic Resource
    Observation of spin-glass freezing in the S=1 linear-chain Heisenberg antiferromagnet NENP : The 40th annual conference on magnetism and magnetic materials (1996)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 79 (1996), S. 6167-6169 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have observed spin-glass freezing in a nominally pure single crystal of the S=1 linear-chain Heisenberg antiferromagnet Ni(C2H8N2)2NO2(ClO4)(NENP) by direct current (dc), linear alternating current (ac), and nonlinear ac susceptibility measurements. A possible origin of this spin-glass freezing is discussed. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.362061
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  • 2
    Electronic Resource
    Electronic Resource
    EFFECTS OF DRAWING STRAIN AND BLUING ON THE FATIGUE STRENGTH OF EUTECTOID STEEL WIRES (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Fatigue & fracture of engineering materials & structures 20 (1997), S. 0 
    Details
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract— The effects of bluing, associated with drawing strain, on the fatigue strength of eutectoid steel wires have been investigated. The fatigue limit increases by bluing and the increase is more significant with higher drawing strain. The peak in the fatigue limit with regard to the drawing strain in the wires, at a strain of 2.5, disappears after bluing. On the other hand, in the ferritic steel wires investigated for comparison, the fatigue limit gradually increases with the drawing strain up to 7.7. Furthermore, no appreciable change in the fatigue limit due to bluing is found. Based on the results of hardness tests on fatigue specimens with- and without-bluing, it is deduced that the decrease of the fatigue limit beyond the peak drawing strain in the eutectoid steel wire can partly be attributed to insufficient locking of the high-density dislocations by solute atoms. The effect of relaxation of residual stress during bluing is also briefly discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-2695.1997.tb01520.x
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  • 3
    Electronic Resource
    Electronic Resource
    Immunohistochemical Localization of the Epidermal Growth Factor-Receptor in Rhesus-monkey Prostate (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Anatomia, histologia, embryologia 25 (1996), S. 0 
    Details
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Epidermal growth-factor receptor (EGF-r), a membranebound glycoprotein activated by EGF, is important in maintaining the integrity and function of the prostate. To investigate EGF-r presence in the prostate of the rhesus monkey, monoclonal-antibody immunohistochemical examination was performed. The monkey prostate consisted of the cranial and caudal lobes, and the prostatic epithelial cells were composed of the secretory and basal cells. The distribution patterns of EGF-r in the prostatic epithelial cells were quite different between the cranial and caudal lobes. In the caudal lobe, EGF-r was seen in both secretory and basai cells, whereas, in the cranial lobe, the EGF-r was seen exclusively in the basal cells. The stromal cells of both lobes did not show EGF-r. This study revealed that each prostatic lobe contains specific binding sites for EGF, indicating a biological difference between the two lobes of the prostate of the rhesus monkey.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1439-0264.1996.tb00066.x
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  • 4
    Electronic Resource
    Electronic Resource
    AQUAPORIN-2 AND -3: Representatives of Two Subgroups of the Aquaporin Family Colocalized in the Kidney Collecting Duct (1998)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Physiology 60 (1998), S. 199-220 
    Details
    ISSN: 0066-4278
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine , Biology
    Notes: Abstract Since the molecular identification of the first aquaporin in 1992, the number of proteins known to belong to this family has been rapidly increasing. These members may be separated into two subgroups based on gene structure, sequence homology, and function. Regulation of the water permeability of the collecting ducts of the kidney is essential for urinary concentration. Aquaporin-2 and -3, which are representative of these subgroups, are colocalized in the collecting ducts. Understanding these subgroups will elucidate the differences between aquaporin-2 and -3. Aquaporin-2 is a vasopressin-regulated water channel located in the apical membrane, and aquaporin-3 is a constitutive water channel located in the basolateral membrane. In contrast to aquaporin-3, which appears to be less well regulated, many studies have now identified multiple regulational mechanisms at the gene, protein, and cell levels for aquaporin-2, thus reflecting its physiological importance. Evidence of the participation of aquaporin-2 in the pathophysiology of water-balance disorders is accumulating.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.physiol.60.1.199
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  • 5
    Electronic Resource
    Electronic Resource
    High-pressure Brillouin study of solid HBr at pressures up to 7 GPa (1999)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 111 (1999), S. 10617-10621 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: High-pressure Brillouin scattering measurements have been carried out in orientationally disordered (OD) phases I and I′ of solid HBr, which yielded the first determination of acoustic velocities for all directions, the refractive index, the polarizability, the density, adiabatic elastic constants (C11, C12, and C44), bulk modulus, and the elastic anisotropy as a function of pressure up to 7 GPa and at room temperature. The I→I′ phase transition in solid HBr was confirmed on the discontinuous pressure dependence at P=2.3 GPa for average errors of the least-squares fit by the analysis of in situ Brillouin spectroscopy. These elastic properties of solid HBr are compared with recent results in the OD phase I of solid HCl. We suggest that the form of the potential energy function for intermolecular forces in solid HBr is similar to that in HCl. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.480414
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  • 6
    Electronic Resource
    Electronic Resource
    Influence of prostaglandin F2α and its analogues on hair regrowth and follicular melanogenesis in a murine model (2005)
    Oxford, UK; Malden, USA : Munksgaard International Publishers
    Experimental dermatology 14 (2005), S. 0 
    Details
    ISSN: 1600-0625
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract:  Latanoprost and isopropyl unoprostone, which are analogues of prostaglandin F2α (PGF2α), are promising drugs for the reduction of intra-ocular pressure. However, they have been reported to have side effects, including hypertrichosis and hyperpigmentation of the eyelashes and periocular skin, and occasionally poliosis. In order to investigate these effects further, PGF2α, latanoprost and isopropyl unoprostone were applied to the dorsal skin of 7-week-old C57BL/6 mice, and hair length was measured during the treatment. The three molecules all showed stimulatory effects on the murine hair follicles and the follicular melanocytes in both the telogen and anagen stages, and stimulated conversion from the telogen to the anagen phase. PGE2 is known to act synergistically with PGF2α, and hence the influence of PGE2 was also examined. PGE2 did not induce distinct telogen-to-anagen conversion, but showed moderate growth stimulatory effects on early anagen hair follicles. In addition, we observed a case of hypertrichosis and trichomegaly with an excess of melanogenesis, leading to the emergence of white hair, suggesting that poliosis can occur as a side effect of eye treatment with solutions of PGF2α analogues. The stimulatory effects of PGF2αand PGE2 on hair growth have been discussed with regard to the role of protein kinase C and mast cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0906-6705.2005.00270.x
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  • 7
    Electronic Resource
    Electronic Resource
    EFFECTS OF GAMMA-LINOLENIC AND EICOSAPENTAENOIC ACIDS ON BLOOD PRESSURE IN SHR (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 22 (1995), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. The present study was performed to determine whether chronic treatments with gamma linolenic acid (n-6, GLA) or eicosapentaenoic acid (n-3, EPA) would alter serum and red blood cell (RBC) unsaturated fatty acid composition, and to determine whether these treatments would affect blood pressure (BP), serum lipid metabolism and the development of atherosclerosis in spontaneously hypertensive rats (SHR).2. To compare the effects on atherosclerosis, some SHR were denuded of aortic endothelium so that the development of atherosclerosis would be accelerated. Olive oil (control), GLA or EPA (low dose: 5 mg/day per rat, high dose: 50 mg/day per kg, respectively) was administered intraperitoneally for 6 weeks in SHR.3. GLA treatments increased GLA and its metabolite, dihomo-GLA, levels in serum but not in RBC, while EPA treatments increased EPA level both in serum and in RBC.4. The BP of control SHR was further elevated. EPA significantly reduced this elevation of systolic, mean and diastolic pressure within the first week and thereafter, whereas GLA did not affect BP elevation. Neither heart rate or bodyweight gain was affected by these treatments.5. Serum total cholesterol (TC), triglyceride (TG), and glucose (G) levels and the development of atherosclerosis were unaffected by either GLA or EPA treatment.6. In summary, chronic EPA but not GLA treatment slightly reduced BP elevation in SHR. Although chronic GLA or EPA treatment increased the respective serum level, these treatments unaltered serum TC, TG and G levels, and could not prevent the development of aortic atherosclerosis in SHR.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1995.tb02930.x
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  • 8
    Electronic Resource
    Electronic Resource
    HYPOTHALAMIC AND MEDULLARY GABAA AND GABAb-ERGIC SYSTEMS DIFFERENTLY REGULATE SYMPATHETIC AND CARDIOVASCULAR SYSTEMS (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 22 (1995), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. To determine whether hypothalamic and medullary GABA (gamma-aminobutyric acid)B stimulation would affect the sympathetic and cardiovascular activities, and to determine whether these effects would be altered in hypertension, baclofen (a GABAb agonist) was injected into a hypothalamic pressor area (ventromedial hypothalamus, VMH), a depressor area (anterior hypothalamus, AH), or a nucleus tractus solitarius (NTS) in normotensive and spontaneously hypertensive rats (SHR).2. Intracetebroventricular (ICV) injections of a GABAa agonist (muscimol, 1 μg) decreased blood pressure (BP) and heart rate (HR). ICV injections of baclofen (2μg) elicited biphasic depressor and pressor effects, and these effects were abolished by a pretreatment with saclofen (GABAb antagonist, 100 μg, icv).3. Muscimol (400 ng) and baclofen (800 ng) injected into VMH decreased sympathetic nerve activity (SNA), BP and HR to almost similar levels, while saclofen injected into VMH increased HR without affecting BP levels.4. The same dose of baclofen injected into AH increased BP, but muscimol (AH) did not alter BP.5. Both muscimol and baclofen injected into NTS increased BP, but its magnitude was larger in baclofen injections.6. Depressor and sympathoinhibitory effects of baclofen (VMH) in SHR were larger than those in normotensive Wistar-Kyoto (WKY) rats, while pressor responses elicited by baclofen (AH) did not differ between SHR and WKY.7. In summary, GABA reduces SNA, BP and HR through both GABAa and GABAb receptors in VMH. In addition, the GABAb system acts on AH and NTS to further regulate the cardiovascular activities. In SHR, GABAB-ergic dysfunction in VMH but not in AH might contribute to the development of hypertension.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1995.tb02966.x
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  • 9
    Electronic Resource
    Electronic Resource
    Effects of post-drawing treatments on the fatigue strength of eutectoid steel wires (1999)
    Oxford, UK : Blackwell Science Ltd
    Fatigue & fracture of engineering materials & structures 22 (1999), S. 0 
    Details
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1460-2695.1999.00212.x
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  • 10
    Electronic Resource
    Electronic Resource
    Linear porokeratosis with multiple squamous cell carcinomas: sludy of p53 expression in porokeratosis and squamous cell carcinoma (1996)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 134 (1996), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1996.tb07965.x
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