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  • 1
    Electronic Resource
    Electronic Resource
    Hypersensitivity pneumonitis with antibodies to Cryptococcus neoformans (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 8 (1978), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Clinical and immunological studies were made in forty-two patients diagnosed as suffering from hypersensitivity pneumonitis at Osaka Prefectural Habikino Hospital between 1973 and 1977. All the sera from forty-one patients tested had high litres of antibody against Cryptococcus neoformans in indirect fluorescent antibody tests, and twelve also had precipitins against Cryptococcus neoformans polysaccharide. Only about 10% of control sera from patients with otherlung diseases had low titresof antibody against Cryptococcus neoformans. Antibody against Cryptococcus neoformans was also found frequently in the sera of asymptomatic members of the families of the patients. A possible relationship of Cryptococcus neoformans to hypersensitivity pneumonitis is suggested.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1978.tb01503.x
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  • 2
    Electronic Resource
    Electronic Resource
    Japanese summer-type hypersensitivity pneumonitis: studies using Cryptococcus antigen (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 12 (1982), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Sixty-six patients, diagnosed as Japanese summer-type hypersensitivity pneumonitis at Osaka Prefectural Habikino hospital between 1973 and 1980, were studied. The diagnosis was based on the clinical features and summer-seasonal nature of the disease. The presence of an aetiological agent within patients' home environment was suggested by the recurrence of acute symptoms of high fever, cough and dyspnoea 5–8 hr after coming home from hospital, and by spontaneous improvement on leaving home. Immunological studies revealed the presence of anti-Cryptococcus antibody in sixty-four of sixty-five patients' sera, by indirect immunofluorescence against Cryptococcus neoformans, Precipitating antibody against culture supernatant protein-antigen of Cr. neoformans was detected in more than 80% of sera obtained from patients during the active stage of the disease. The positive result on inhalation provocation-challenge, using culture supernatant protein-antigen, suggested that Cr. neoformans or antigenically related Cryptococcus species may cause Japanese summer-type hypersensitivity pneumonitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1982.tb02538.x
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  • 3
    Electronic Resource
    Electronic Resource
    ATX-S10(Na)–photodynamic therapy is less carcinogenic for mouse skin compared with ultraviolet B irradiation (2005)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 153 (2005), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Photodynamic therapy (PDT) is available for the treatment of various skin tumours and other skin diseases. Ultraviolet (UV) irradiation induces DNA damage, cyclobutane pyrimidine dimers (CPD) (6-4) photoproducts (6-4PP) and 8-hydroxy-2′-deoxyguanosine (8-OHdG), all of which are carcinogenic for the skin. However, effects of PDT on DNA damage and carcinogenesis are unclear.Objectives  To compare the production of photoproducts and the induction of skin tumours in mouse epidermis treated with UVB or PDT.Methods  We performed UVB irradiation or ATX-S10(Na)–PDT on the skin of 20 hairless mice, in each case, and analysed DNA damage and tumour induction.Results  After a single irradiation of UVB on mouse skin, CPD, 6-4PP and 8-OHdG were detected in the nuclei of keratinocytes. In contrast, PDT-treated mouse keratinocytes showed induction of 8-OHdG, but not of CPD or 6-4PP. Skin tumours induced by UVB irradiation (3 kJ m−2 three times weekly) were observed following 15 weeks of irradiation (mean ± SEM tumour incidence 3·2 ± 1·8%; tumour number 3·2 ± 1·6 per mouse) and increased depending on irradiation times and doses. Following 30 weeks of UVB irradiation (3 kJ m−2 three times weekly), mean ± SEM tumour incidence and tumour number were 28·7 ± 4·8% and 14·2 ± 2·8% per mouse, respectively. Although skin tumours were also detected in PDT-treated mouse skin following 80 weeks of treatment (mean ± SEM tumour incidence 9·1 ± 1·8%; tumour number 12·2 ± 2·3 per mouse), the number of tumours was not statistically different from untreated mouse skin (mean ± SEM tumour incidence 4·1 ± 3·8%; tumour number 5·2 ± 3·3 per mouse).Conclusions  PDT induced 8-OHDG but not CPD or 6-4PP, and was shown to be a relatively safe modality following multiple applications to mouse skin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.2005.06937.x
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  • 4
    Electronic Resource
    Electronic Resource
    On extrinsic faults in face-centred cubic crystals (1978)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 34 (1978), S. 344-346 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: Application of the matrix intensity equation of X-ray diffraction is discussed for the second problem of extrinsic faults in face-centred cubic crystals, discussed by Howard [Acta Cryst. (1977), A33, 29-32]. The second problem is generalized to the case that the probability with which inserted layers follow layers of the original crystal differs from that with which inserted layers follow previously inserted layers. The Q matrix for the case is obtained and the results of intensity calculation are shown.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0567739478000637
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  • 5
    Electronic Resource
    Electronic Resource
    Cultivation of larvae of Japanese eel (1976)
    [s.l.] : Nature Publishing Group
    Nature 263 (1976), S. 412-412 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Silver eels were collected in the Hiranuma and Mabuchi Rivers in Aomori prefecture (Japan) in September 1975. Females and males were matured with repeated injections of chum salmon pituitary homogenate and Synahorin (Teikoku Zoki), respectively5,6. Eggs were stripped from the females, placed into ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/263412a0
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  • 6
    Electronic Resource
    Electronic Resource
    Effect of Helium and Aging Treatment on Radiation Damage Behavior in Low Activation Fe-Cr-Mn (W, V) Alloy (2005)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 475-479 (Jan. 2005), p. 1455-1458 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The effects of helium and aging treatment on radiation damage behavior in low activation Fe-Cr-Mn ( W, V) alloy were investigated by electron and helium ion dual-beam irradiation in a high voltage electron microscope. Specimens were aged at 673 K, 823 K and 923 K for 1000, 3000 and 10000 hours. Electron and He ion dual-beam irradiations were performed at 627 K to 10 dpa. M23C6 type carbides were precipitated in the aged specimens, and the amount of the precipitates was increased with increasing aging temperature and aging time. He bubbles were formed during dual-beam irradiation in all of the specimens. The cavity swelling under dual-beam irradiations was increased with increasing the aging temperature and aging time. It was suggested that cavity swelling is closely related to the concentration of solutes such as Cr and C in the matrix, namely cavity growth rate becomes higher with decreasing of the solutes in solution
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/09/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.475-479.1455.pdf
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  • 7
    Electronic Resource
    Electronic Resource
    Intraparticle diffusivity of methylene blue into porous activated carbon (1981)
    Springer
    Bulletin of environmental contamination and toxicology 27 (1981), S. 610-615 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01611071
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  • 8
    Electronic Resource
    Electronic Resource
    Intraparticle diffusivity of methylene blue into pores of activated carbon and pyrolysis ash derived from organic surplus sludge (1983)
    Springer
    Bulletin of environmental contamination and toxicology 30 (1983), S. 141-146 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01610112
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  • 9
    Electronic Resource
    Electronic Resource
    Study of Static Electricity in Wafer Cleaning Process (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Solid state phenomena Vol. 134 (Nov. 2007), p. 263-266 
    Details
    ISSN: 1662-9779
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/24/transtech_doi~10.4028%252Fwww.scientific.net%252FSSP.134.263.pdf
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  • 10
    Electronic Resource
    Electronic Resource
    The twitcher mouse: An ultrastructural study on the oligodendroglia (1983)
    Springer
    Acta neuropathologica 59 (1983), S. 159-166 
    Details
    ISSN: 1432-0533
    Keywords: Twitcher mouse ; Oligodendroglia ; Cellular degeneration ; Myelin sheaths ; Globoid cell leukodystrophy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Morphological alterations of oligodendroglia were investigated in the spinal cord of the twitcher mouse, an authentic murine model of human globoid cell leukodystrophy (GLD) from day 5 to day 45 postnatal (p.n.). Typical inclusions were seen in the perikarya as well as the processes of oligodendroglia after day 10 with increasing frequency. The majority of the inclusions was non-crystalloid but rather needle-like or slender tubular in appearance. Ultrastructural features of cellular degeneration became first noticeable on days 25–30 in the oligodendroglial cytoplasm. These consisted of an increased number of microtubules and/or smooth cisterns, dispersed ribosomes, alteration of endoplasmic reticulum forming stacked lamellae or whorles, vesiculation or vacuolation of cytoplasm. The number of degenerating oligodendroglia increased in the older twitcher mice, so did the degenerating myelin sheath. However, even on day 45, when globoid cells became conspicuous in subpial and perivascular regions, many oligodendroglia and myelin sheaths were still well preserved. These observations suggested that oligodendrogial degeneration resulted in the degeneration of myelin sheaths but globoid cells appeared even before morphological evidence of myelin degeneration, presumably in response to the biochemical alterations resulted from the deficiency of galactosylceramidase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00703199
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