Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 2005-2009  (2)
  • 1960-1964  (6)
  • 1940-1944  (2)
  • 1930-1934  (1)
Material
Years
Year
  • 1
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background The T cell reactivity to the major allergen of bee venom, phospholipase A2, has been thoroughly characterized. In contrast, only little is known about the human cellular response to major allergens from wasp venom.Objective To characterize the human T cell response to antigen 5 from Vespula vulgaris, Ves v 5.Methods Recombinant Ves v 5 was used to establish allergen-specific T cell lines (TCL) and T cell clones (TCC) from the peripheral blood of vespid-allergic and non-allergic individuals. Ves v 5-specific TCL were mapped for T cell epitopes using overlapping synthetic peptides representing the complete amino acid sequence of Ves v 5. Ves v 5-specific TCC were analysed for antigen-induced secretion of IL-4, IFN-γ and IL-10.Results Seventeen distinct T cell epitopes were recognized by allergic individuals among which Ves v 5181–192 was identified as a dominant T cell epitope. Partially different epitopes were observed in TCL from non-allergic subjects and the dominant epitope Ves v 5181–192 was not prevalent in these cultures. Ves v 5-specific TCC isolated from allergic individuals did not show the typical T helper type 2 (Th2)-like cytokine profile in response to specific stimulation, i.e. high amounts of IL-4 and low IFN-γ. TCC from non-allergic individuals showed a Th1-like cytokine pattern.Conclusions Our findings provide evidence that the allergic T cell response to Ves v 5 is not Th2-dominated and that different immunogenic sites on this major wasp venom allergen are recognized by allergic and non-allergic individuals.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background:  Atopic disorders are the result of complex interactions between genetic and environmental factors. Associations analyses between the promoter polymorphism rs1800875 in the mast cell chymase gene (CMA1) and atopy-related phenotypes have yielded inconsistent results.Methods:  We sequenced the CMA1 locus in 24 unrelated healthy individuals with serum IgE levels 〈50% percentile and 24 individuals with atopic eczema and serum IgE levels 〉90% percentile. Seven CMA1 single nucleotide polymorphisms (SNPs) were evaluated for evidence of associations with atopic phenotypes within a large population of German adults (n = 1875). Subjects were phenotyped by standardized questionnaires and interviews, skin prick testing and serum IgE measurements. Genotyping was performed using MALDI-TOF MS (Matrix-Assisted Laser Desorption Ionization–Time of Flight mass spectrometry).Results:  Promoter polymorphism rs1800875 was significantly associated with atopic eczema. No associations between any other single SNP and atopic phenotypes could be detected. Haplotype reconstruction revealed four of 128 possible haplotypes reaching estimated frequencies of 3% or more. Two of these haplotypes showed a borderline-significant association with atopic eczema, which did not remain significant after correction for multiple testing.Conclusions:  Results confirm previous observations of a significant association between the CMA1 promoter polymorphism rs1800875 and atopic eczema, but not with serum IgE levels, and support the hypothesis that CMA1 serves as candidate gene for atopic eczema.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Microchimica acta 48 (1960), S. 592-596 
    ISSN: 1436-5073
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Summary The color reaction of indole with aldehydes in concentrated hydrochloric acid, which up till now has been used as a test for indole, can be employed as a general sensitive and specific test for aldehydes. If carried out as a spot test aldehydes can be detected in very small amounts.
    Abstract: Résumé On applique comme procédé de recherche général, sensible et spécifique des aldéhydes, la réaction colorée de l'indole avec les aldéhydes dans l'acide chlorhydrique concentré, qui, jusqu'à maintenant, trouvait une application seulement comme recherche de l'indole. En exécutant la réaction comme recherche à la touche, on peut établir la présence de très petites quantités d'aldéhydes.
    Notes: Zusammenfassung Die Farbreaktion von Indol mit Aldehyden, die bis jetzt lediglich als Indolnachweis empfohlen worden ist, ermöglicht einen allgemeinen, empfindlichen und spezifischen Aldehydnachweis. In der Arbeitsweise der Tüpfelanalyse können kleinste Mengen Aldehyde nachgewiesen werden.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Microchimica acta 50 (1962), S. 501-503 
    ISSN: 1436-5073
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Summary Aliphatic and aromatic disulfides and diselenides are reduced selectively by nickel-aluminium alloys (50/50) in hydrochloric acid-alcohol to yield thiols or selenols, which in their turn can be detected through the iodine-azide reaction. This permits a selective detection of disulfides in the absence of other compounds which react positively with the iodine-azide solution (thiols, thiones, mustard oils, thio acids, and derivatives).
    Abstract: Résumé L'alliage nickel-aluminium (50/50), dans le mélange alcool-acide chlor — hydrique, permet de réduire sélectivement les bisulfures et les biséléniures aliphatiques et aromatiques, en thiols ou en sélénols que l'on peut alors caractériser par la réaction à l'iode-azoture. Ceci rend possible une recherche sélective des bisulfures en l'absence d'autres composés donnant une réaction positive avec la solution à l'iode-azoture (thiols, thiones, essences de moutarde, acides du soufre et dérivés).
    Notes: Zusammenfassung Alphatische und aromatische Disulfide und Diselenide werden selektiv durch Nickel-Aluminiumlegierung (50/50) in salzsaurem Alkohol zu Thiolen bzw. Selenolen reduziert, die ihrerseits mittels der Jodazidreaktion nachgewiesen werden können. Dies ermöglicht einen selektiven Nachweis von Disulfiden bei Abwesenheit anderer mit Jodazidlösung positiv reagierender Verbindungen (Thiole, Thione, Senföle, Thiosäuren und Derivate).
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1436-5073
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Summary Aromatic andα,β-dicarbonyl compounds as well as 1,2-dicarbonyl compounds condense withp-nitrophenylhydrazine to yield the correspondingp-nitrophenyl hydrazones or di-p-nitrophenylhydrazones. By alkalization these products are rearranged into colored nitronic acid salts. These reactions permit the selective detection of aromatic andα,β-unsaturated carbonyl compounds, for which no chemical procedure has been known previously.
    Abstract: Résumé Les composés carbonylésα,β-non saturés et aromatiques ainsi que les composés dicarbonylés-1,2 se condensent par lap-nitrophénylhydrazine enp-nitrophénylhydrazones ou di-p-nitrophénylhydrazones correspondantes. Celles-ci sont transposées par alcalinisation en sels colorés de l'acide nitronique. Ces réactions permettent la recherche sélective des composésα,β-non saturés et aromatiques pour lesquels on ne connaissait pas de procédé chimique jusqu'à maintenant.
    Notes: Zusammenfassung Aromatische undα, β- ungesättigte Carbonylverbindungen sowie 1,2-Dicarbonylverbindungen kondensieren mit p-Nitrophenylhydrazin zu entsprechenden p-Nitrophenylhydrazonen bzw. Di-p-Nitrophenylhydrazonen. Diese werden durch Alkalisierung in farbige Nitronsäuresalze umgelagert. Diese Reaktionen gestatten den selektiven Nachweis aromatischer undα,β-ungesättigter Carbonylverbindungen, wofür bisher kein chemisches Verfahren bekannt war.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    facet.materialart.
    Unknown
    Urbana, etc. : Periodicals Archive Online (PAO)
    American Journal of Psychology. 77:3 (1964:Sept.) 485 
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 87 (1962), S. 133-140 
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung 1. Durch Verabfolgung eines Pankreas-Fermentpräparates wird die Proteolyse im Magen von Säuglingen im Gegensatz zu einem Magen-Fermentpräparat wesentlich erhöht. 2. Die proteolytischenph-Aktivitätskurven der in vitro-Untersuchungen bestätigen die Wirksamkeit des Pankreas-Fermentpräparates in demph-Bereich dieser Altersgruppe. 3. Magen- und Pankreas-Fermentpräparate beeinflussen die Magen-proteolyse bei gesunden Kindern der Altersgruppe 2–12 Jahre nicht meßbar. 4. Die im Magen unter Magen- und Pankreas-Fermentzusatz freigesetzten Aminosäuren entsprechen sich weitgehend. 5. Verabfolgung des Pankreas-Fermentpräparates hat eine Verzögerung der Magenentleerung zur Folge, deren Ursache noch unklar ist.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Fresenius' Zeitschrift für analytische Chemie 98 (1934), S. 374-377 
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Colloid & polymer science 90 (1940), S. 51-58 
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Zusammenfassung 1. Die Hurrell'sche Kolloidmühle als Apparatur zur Erzeugung extrem hoher Verschiebungsgeschwindigkeiten wird theoretisch behandelt. 2. Lösungen verschiedener Stärkearten, und zwar Vertreter der Wurzel-, Samen- und Stammstärken werden extrem hohen Verschiebungsgeschwindigkeiten von 3,9 · 105 sec−1 ausgesetzt. 3. Es wird festgestellt, daß in allen Fällen hohe Viskositätsverluste (bis 98 Proz. der ursprünglichen Viskosität) infolge der mechanischen Behandlung eintreten. 4. Die Höhe des Viskositätsverlustes kann mit dem quellungsanalytischen Verhalten der betreffenden Stärkeart in Zusammenhang gebracht werden. 5. Den stärksten Viskositätsverlust erleiden solche Losungen, in denen die Stärke während des Quellungsverlaufes intermediär das größte Kornvolumen bei gleichzeitiger Stabilität des Kornes annimmt. 6. Der Viskositätsunterschied der einzelnen Stärkearten verschwindet weitgehend infolge der mechanischen Behandlung. Dieser viskosimetrische Ausgleich kann als Zurückführung auf die natürliche Viskosität der Stärke, unbeeinflußt durch quellungsphänomenologische Vorgänge aufgefaßt werden.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Colloid & polymer science 93 (1940), S. 207-224 
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...