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  • 1
    Electronic Resource
    Electronic Resource
    Measurement of salinity distributions in salt-stratified, double-diffusive systems by optical deflectometry (1986)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 57 (1986), S. 2538-2542 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Reliable salinity measurements in double-diffusive thermohaline solutions are necessary to understand relevant system behavior. An optical technique, which has previously been used to investigate solute diffusion in isothermal systems, is employed to measure the salinity distribution in a double-diffusive thermohaline system. The technique is verified by comparison with independent salinity measurements, and its use in a double-diffusive system reveals detailed salinity distribution information. When used with the shadowgraph method of flow visualization, the salinity measurement technique permits a more quantitative interpretation of the shadowgraphic results.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1139107
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  • 2
    Electronic Resource
    Electronic Resource
    PARTIAL PURIFICATION AND CHARACTERIZATION OF AN ACID RIBONUCLEASE IN BEEF BRAIN NUCLEI (1975)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 25 (1975), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— In this report we describe the partial purification and characterization of an acid ribonuclease from beef brain nuclei (RNAase BN2). RNAase BN2 was purified approximately 85-fold. The optimum pH is 6-2 and the optimum temperature 55°C. The effect of ions on the RNAase BN2 and its Km were determined. RNAase BN2 is an endoribonuclease capable of hydrolysing polyA, polyU and polyC. Oligonucleotides produced by the hydrolysis of polyA by the RNAase BN2 have a monophosphate group at the 3′ position.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1975.tb12245.x
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  • 3
    Electronic Resource
    Electronic Resource
    Description of a new disease condition occurring in farmed coho salmon, Oncorhynchus kisutch (Walbaum), in South America (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 14 (1991), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Abstract. High levels of mortalities have been experienced in farmed coho salmon, Oncorhynchus kisuteh (Walbaum), in the Gulf of Ancud, southern Chile. Most affected fish had similar skin lesions ranging from small areas of raised scales through white raised plaques to shallow ulcers. The fish were also generally dark, lethargic and anorexic. However, some affected fish appeared grossly normal with no skin lesions. Internal pathology consisted of varying degrees of ascites, peritonitis and general pallor. Spleens were generally enlarged. Kidneys and livers were swollen and grey in colour, often with pale focal lesions. Extensive histopathology was present in affected fish with tissue necrosis, intravascular necrotic thrombi, large basophilic cells and basophilic granules, some free in the tissues, some contained within cells. The basophilic granules, known locally as the ‘UA’, or unidentified agent, were thought to be the main aetiological agent, and are likely to be a rickettsia-like organism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.1991.tb00585.x
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  • 4
    Electronic Resource
    Electronic Resource
    Intradermal testing of fixed drug eruption (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 51 (1996), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.1996.tb04505.x
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  • 5
    Electronic Resource
    Electronic Resource
    Cross-reactivity between obeche wood (Triplochiton scleroxylon) and natural rubber latex (2004)
    Oxford, UK : Munksgaard International Publishers
    Allergy 59 (2004), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background:  Several studies have shown that allergy to natural rubber latex is associated with cross reactivity to other plants. We have investigated a possible cross reactivity with a tree belonging to the Sterculiaceae family, Tryplochiton scleroxylon, in a patient allergic to obeche wood, that began to suffer symptoms of allergy in contact with latex.Methods:  Determinations of specific IgE by CAP to obeche, natural rubber latex (NRL) and recombinant allergens of latex were done. Immunoblotting was performed to study allergens detected by serum of our patient. CAP-inhibition methods were used to study cross-reactive between NRL and obeche wood.Results:  In obeche extract, 4 bands were found of an apparent molecular weight of 18, 38, 75 and 199 kDa. In NRL extract the allergens have a molecular weight around 18, 21, 32, 38, 60, 70 and 199 kDa. IgE to latex was almost completely inhibited (96%) by the obeche extract in CAP-inhibition studies. Using obeche extract as inhibitor, IgE binding to native hevein (nHevb 6.02) was reduced by 25%.Conclusions:  The results obtained in CAP-inhibition demonstrate the existence of cross-reactivity between proteins in NRL and obeche wood. In our patient, a band of apparent molecular weight of 38 kDa could be the most important allergen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.13989995.2003.00137.x
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  • 6
    Electronic Resource
    Electronic Resource
    Clinical manifestations of allergy to Anisakis simplex (2000)
    Copenhagen : Munksgaard International Publishers
    Allergy 55 (2000), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1398-9995.2000.03405.x
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  • 7
    Electronic Resource
    Electronic Resource
    Prevalence of pollinosis in the Basque Country (1999)
    Copenhagen : Munksgaard International Publishers
    Allergy 54 (1999), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: The prevalence of allergic diseases, mainly pollinosis, has increased within the last decades. Our study aimed to determine the prevalence of sensitization to Poaceae pollen in the Basque Country. This is a region of northern Spain, with an area of 7261 km2 and a population of 2109009 inhabitants. Two different climatic regions may be distinguished in the Basque Country (the Atlantic and the Oceanic). Methods: A transversal study was carried out on 2216 subjects, aged 10–40 years. A personal interview was carried out in order to compile study data, by means of a questionnaire that had been previously validated with a clinical history and an allergy study. Results and Conclusions: Our results show the prevalence of pollinosis in the Basque Country to be 10.6% (C.I. 95% 9.35–11.96%) without significant differences between men and women. The prevalence in the Atlantic climate area (9.71%) was lower than in the Oceanic climate area (13.61%). There were no differences between persons living in a rural environment (10.87%) and those living in an urban setting (10.51%). Pollinosis was more frequent in individuals aged 10–20 (11.41%) and 20–30 (12.54%) than those aged 30–40 years (7.43%). Three features significantly distinguished pollinic from nonpollinic patients:〈list xml:id="l1" style="custom"〉a more common complaint of symptoms after ingestion of Rosaceae fruits or nuts (10.2%)a family history of atopy (8.8%)a greater occurrence of bronchial asthmatic symptoms (23%).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1398-9995.1999.00146.x
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  • 8
    Electronic Resource
    Electronic Resource
    Anisakis simplex, a relevant etiologic factor in acute urticaria (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 52 (1997), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Del Pozo MD, Audícana M, Diez JM, Muñoz D, Ansotegui IJ, Fernández E, García M, Etxenagusia M, Moneo I, Fernández de Corres L. Anisakis simplex, a relevant etiologic factor in acute urticaria. Anisakis simplex, a parasite of fish and cephalopods, can induce IgE-mediated reactions. This study aimed to determine the etiologic role of A. simplex in patients affected by urlicaria/angioedema ‘AE’ or anaphylaxis. We studied 100 adult subjects suffering acute episodes of urticaria/AE, by anamnesis, prick tests with A. simplex and fish-mix extracts, and total and specific IgE to both A. simplex and cod. The following criteria of A. simplex allergy were considered: 1’ urticaria/AE within 6 h after fish ingestion; 2’ specific IgE to A. simplex; 3’ positive prick test to A. simplex extract; 4’ exclusion of other suspected causes. Double-blind, placebo-controlled food challenge was not carried out because ethical considerations forbid challenge with a parasite. Specific IgE to A. simplex‘〈0.7 kU/1’ was found in 22 subjects, but only eight were diagnosed as having A. simplex allergy. Other allergens were involved in 37 patients, and 55 cases were considered idiopathic. Specific IgE to fish ‘〈0.7 kU/1’ was found in two patients, but only one was diagnosed as having fish allergy. We concluded that A. simplex is an important etiologic factor in acute urticaria. We suggest that it should be considered in cases of urticaria/AE or anaphylaxis, especially after fish ingestion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.1997.tb02603.x
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  • 9
    Electronic Resource
    Electronic Resource
    Engagement of visual fixation suppresses sensory responsiveness and multisensory integration in the primate superior colliculus (2003)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 18 (2003), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Neurons in the intermediate and deep layers of the superior colliculus (SC) often exhibit sensory-related activity in addition to discharging for saccadic eye movements. These two patterns of activity can combine so that modifications of the sensory response can lead to changes in orienting behaviour. Can behavioural factors, however, influence sensory activity? In this study of rhesus monkeys, we isolate one behavioural factor, the state of visual fixation, and examine its influences on sensory processing and multisensory integration in the primate SC. Two interleaved fixation conditions were used: a FIX condition requiring exogenous fixation of a visible fixation point; and a FIX-BLINK condition, requiring endogenous fixation in the absence of a visible fixation point. Neurons of the SC were influenced by fixation state, exhibiting both lower levels of sensory activity and reduced multisensory interactions when fixation was exogenously engaged on a visible fixation point. These results are consistent with active visual fixation suppressing responses to extraneous stimuli, and thus demonstrate that sensory processing and multisensory responses in the SC are not dependent solely on the physical properties of the sensory environment, but are also dynamically influenced by the behavioural state of the animal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9568.2003.02976.x
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  • 10
    Electronic Resource
    Electronic Resource
    Pickled onion-induced asthma: a model of sulfite-sensitive asthma? (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 25 (1995), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: Asthma elicited by sulfite ingestion has been mainly described in steroid-dependent and in non-atopic asthmatics. We have studied a group of 18 young extrinsic asthmatics who presented with asthma attacks immediately after eating pickled onions.Objective: The aim of this study is to ascertain if these asthma attacks are elicited by sulfites contained in pickled onions and the influence of the dose and pH of onions.Methods: The bronchial hyperreactivity of the patients was assessed by a methacho-line challenge test. Oral challenge tests were performed with sodium metabisulfite (MBS) diluted in lemon juice at pH 4.2 and at pH 3.3 (only in patients who did not react with pH 4.2). Two types of pickled onion, Spanish and Dutch pickled onions, were used for oral challenge in seven of the patients. The Monier-Williams method was used to measure the SO2 concentration in pickled onions.Results: The oral provocation test with MBS, pH 4.2, elicited a positive response in six patients (33.3%) and the test at pH3.3 was positive in three out of 12. No significant difference in PD20 values was found between these groups. Three of the seven patients challenged with Spanish pickled onions had a positive reaction but had no reaction with Dutch pickled onions. The SC2 concentration in Spanish pickled onions varied between 765 and 1182 ppm while in Dutch pickled onions were 200 ppm; this exceeded the permitted level (100 ppm). SO2 release in Spanish pickled onion samples was nearly 2.5 times higher when the pH of the sample decreased from 4.2 to 3.3.Conclusion: High levels of SO2 in Spanish pickled onions, and their low pH (3.3) would be the responsible factors of the asthmatic outbreaks after ingestion of Spanish pickled onions by these patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1995.tb00006.x
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