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  • 2000-2004  (2)
  • 1995-1999  (5)
  • 1960-1964  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    023
The Use of Cilostazol in the Treatment of Raynaulds Disease with Digital Ischemia and Tissue Loss (2004)
    Oxford, UK; Malden, USA : Blackwell Science Ltd/Inc.
    Wound repair and regeneration 12 (2004), S. 0 
    Details
    ISSN: 1524-475X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: More than three quarters of patients with a connective tissue disorder will develop secondary Raynauld’s disease. This more severe form of the Raynauld’s can lead to digital ischemia, tissue loss and may even result in the need for amputation of one or more digits. Cilostazol is a phosphodiesterase inhibitor currently approved for use in vascular disease of the lower extremities. Case History: In August of 2002 a 62 year old female pianist with scleroderma presented to the wound clinic with a two year history of intractable digital pain secondary to ischemic ulcerations of the index, long and ring fingers of the right hand. She suffered from secondary Raynauld’s disease. Prior unsuccessful treatments included warming the hands, calcium channel blockade, anticoagulation, topical xylocaine and narcotic analgesics. In August of 2002 cilostazol was started at 100mg BID. Wound care consisted of serial debridement, moist wound healing and topical rhPDGF. Results: Four weeks into treatment the patient’s narcotic requirement decreased substantially and the fingers had a pink appearance. The ring finger healed after eight weeks. At three months the patient discontinued narcotic pain medication. Nine months into treatment the index finger had healed and she resumed playing the piano. The long finger finally healed one year after she initially presented to the wound clinic. Conclusion: Cilostazol may be an important adjunct in the treatment of secondary Raynauld’s disease particularly when digital ischemia has developed. Acknowledgements: Funding from Otsuka Pharmaceuticals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1067-1927.2004.0abstractx.x
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  • 2
    Electronic Resource
    Electronic Resource
    Eine Vision (1999)
    Springer
    Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 42 (1999), S. 312-313 
    Details
    ISSN: 1437-1588
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001030050106
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Facharzt für Unfallchirurgie (1998)
    Springer
    Der Unfallchirurg 101 (1998), S. 72-73 
    Details
    ISSN: 1433-044X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001130050236
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Zur Verwendung des Impact-Faktors als Maß wissenschaftlicher Leistungen. Beschluß des Präsidiums der Deutschen Gesellschaft für Unfallchirurgie vom 21.06.97 (1997)
    Springer
    Der Unfallchirurg 100 (1997), S. 838-838 
    Details
    ISSN: 1433-044X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001130050200
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Dissolved silica in the Garonne River waters: changes in the weathering dynamics (2000)
    Springer
    Environmental geology 40 (2000), S. 19-26 
    Details
    ISSN: 1432-0495
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract  The major ion chemistry of the Garonne River is indicative of seasonal variations in the weathering dynamics of the drainage basin. Using the geochemical model MEGA for calculation of the contribution of atmospheric CO2 to the total bicarbonate fluxes exported by the Garonne River allows estimations of the concentrations of the major dissolved elements that originate from silicate- and carbonate-rock weathering. The molecular ratio SiO2/Al2O3 was calculated for the 1989–1992 period to identify the main type of weathering in the Garonne River, and montmorillonite was shown to be the major mineral occurring in the weathering products. The seasonal variations of the SiO2/Al2O3 ratio also showed that removal of silica was accelerated during humid periods.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002540000119
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  • 6
    Electronic Resource
    Electronic Resource
    Stress and Texture in Titanium Implants Coatings (1998)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 273-275 (Feb. 1998), p. 667-672 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/03/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.273-275.667.pdf
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  • 7
    Electronic Resource
    Electronic Resource
    Influence of acid rain on CO2 consumption by rock weathering: Local and global scales (1995)
    Springer
    Water, air & soil pollution 85 (1995), S. 1563-1568 
    Details
    ISSN: 1573-2932
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Sulphuric and nitric acids, which are supplied by acid precipitation, take over from carbonic acid in weathering reactions, which induced a decrease of the atmospheric/soil CO2 consumption by weathering (WCO2). In order to quantity this disturbance, one has compared the bicarbonate fluxes determined at the outlet of 2 small catchments (one is substantially disturbed and the other is is weakly disturbed by acid precipitation). Our study shows that, under the influence of acid precipitation, bicarbonate fluxes (i.e. WCO2) are decreased by about 73%. It has also been attempted to simulate at the continental scale, the influence of acid precipitation on WCO2, using a Global Erosion Model (GEM-CO2) recently developed. Several simulations have been performed corresponding to different realistic scenarios of global acid precipitation. In the most pessimistic of these scenarios, the GEM-CO2 simulation shows that the global WCO2 would be decreased by no more than 10%.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00477203
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Die Behandlung traumatischer Hautlücken am Schädel (1961)
    Springer
    Langenbeck's archives of surgery 297 (1961), S. 85-90 
    Details
    ISSN: 1435-2451
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Bei traumatischen Hautlücken am Schädeldach bevorzugen wir die Deckung durch gestielte Hautlappen: 1. weil sie von Anfang an gut ernährt sind und dadurch auch bei nicht sauberen infektiösen Wundflächen verwendet werden können, da sie sicherer einheilen, 2. weil sie unseres Erachtens kosmetisch bessere Ergebnisse erzielen. Es wird darauf hingewiesen, daß besonders bei elektrischen und thermischen Verbrennungen die sorgfältige Vorbehandlung: Hebung des Allgemeinzustandes, gezielte antibiotische Behandlung, örtliche Wundbehandlung, eine unerläßliche Voraussetzung für den Erfolg der plastischen Operationen bildet.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01439739
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    Paper (German National Licenses)
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