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  • 1
    Electronic Resource
    Electronic Resource
    InP/GaAs self-assembled nanostructures: Modelization and experiment (1996)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 80 (1996), S. 1931-1933 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The initial stages of the three-dimensional metal organic vapor phase epitaxy growth of InP/GaAs have been studied by atomic force microscopy and Rutherford backscattering. The results are compared with the predictions of an equilibrium model that predicts an in-plane critical size for island formation. At low growth rates the model fits well the experiments while it needs to be further developed to include kinetic effects at higher growth rates. The experiments indicate a Stranski–Krastanow growth mode with a critical thickness of 2.1 ML. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.362944
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  • 2
    Electronic Resource
    Electronic Resource
    Electronic excitation and oscillator strength of ethyl bromide by vacuum ultraviolet photoabsorption and electron energy loss spectroscopy (2000)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 112 (2000), S. 6285-6292 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The high resolution vacuum ultraviolet photoabsorption spectrum of ethyl bromide has been recorded between 5 and 10.15 eV (248–122 nm) using synchrotron radiation. It exhibits a broad structureless valence band centred at 6.1 eV of low cross section followed by a region dominated by excitation of Rydberg states. A high resolution photoelectron spectrum (PES) of the lowest energy ionization band has been obtained and provides ionization energies necessary for identification of related Rydberg-excited states. Also, analysis of the vibrational fine structure in the PES has allowed identification of the normal vibrational modes excited and their wave numbers in the ion. These data, in turn, have been used in the assignment of the lowest energy photoabsorption bands arising from electron excitation into the 5s Rydberg orbital. The electron energy loss spectrum, recorded from 6.5 to 14.1 eV, under electric-dipole conditions, confirms the magnitude of the photoabsorption cross-section values obtained using the synchrotron radiation and extends the differential and optical oscillator strength values up to 14.004 eV. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.481273
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  • 3
    Electronic Resource
    Electronic Resource
    Electronic excitation and oscillator strength of ethyl iodide by VUV photoabsorption and electron energy loss spectroscopy (1999)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 110 (1999), S. 10307-10315 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: A high resolution VUV photoabsorption spectrum of ethyl iodide has been recorded between 4 and 10.2 eV (310–120 nm) using synchrotron radiation. The spectrum consists of a broad structureless absorption band centered at 4.78 eV, followed by a region dominated by excitation of Rydberg states. A high resolution photoelectron spectrum (PES) of the lowest energy ionization band has been obtained and provides ionization energies necessary for identification of related Rydberg-excited states. Also, analysis of the vibrational fine structure in the PES has allowed identification of the normal vibrational modes excited and their wave numbers in the ion. These, in turn, have been used in the assignment of the lowest energy photoabsorption bands arising from electron excitation into the 6s Rydberg orbital. An electron energy loss spectrum has also been recorded from 5.8 to 14.2 eV, under electric-dipole conditions. It confirms the magnitude of the photoabsorption cross section values obtained using the synchrotron radiation and extends the differential and optical oscillator strength values up to 14.2 eV. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.478964
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  • 4
    Electronic Resource
    Electronic Resource
    Prognostic signs in melanoma: state of the art (2004)
    Oxford, UK : Blackwell Science Ltd
    Journal of the European Academy of Dermatology and Venereology 18 (2004), S. 0 
    Details
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Prognoses for melanoma patients are currently based on statistically confirmed parameters, above all the Breslow thickness and number of lymph node and/or distant metastases. However, metastases can develop even with ‘thin’ melanomas (〈 0.7 mm), while survival has been recorded in patients with tumours classified as ‘thick’ (〉 4 mm). This review of the literature examines the most recent advances in prognostic markers for melanoma (serological, immunohistochemical, histological, genetic and surgical). These markers offer interesting possibilities in terms of diagnostic certainty, identification of early growth phases and estimation of the tumour's potential for progression and metastasis. It is reasonable to assume that their combined use can provide useful information for formulating prognoses that are not only statistically valid but also individualized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1468-3083.2004.00895.x
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  • 5
    Electronic Resource
    Electronic Resource
    Randomized, controlled trial to compare the J-pouch and W-pouch configurations for ulcerative colitis in the maturation period (2000)
    Springer
    Diseases of the colon & rectum 43 (2000), S. 615-620 
    Details
    ISSN: 1530-0358
    Keywords: Ulcerative colitis ; Randomized controlled trial ; Restorative proctocolectomy ; Ileal pouch
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: Proctocolectomy with ileal pouch-anal anastomosis has become the procedure of choice for the treatment of ulcerative colitis. Functional results may differ with different pouch designs. This randomized study aimed to evaluate the relative effectiveness of two-limb J and four-limb W reservoir designs in the so-called maturation period after ileostomy closure. METHODS: Twenty-four patients underwent ileal pouch-anal anastomosis for ulcerative colitis. Eleven were randomly assigned to the J-pouch group and 13 to the W-pouch group. Frequency of defecation and other functional data were collected at 4, 8, and 12 months after ileostomy closure. Maximum tolerated volume was assessed in the same period by a latex balloon inflated with water. Maximum resting anal pressure, maximum voluntary contraction, and the rectoanal inhibitory reflex were assessed in the preoperative period and at 4, 8, and 12 months after ileostomy closure. RESULTS: Frequency of defecation decreased from 4 to 12 months after ileostomy closure in both groups (P=0.04), but patients with a W-pouch had significantly lower values than patients with J-pouches (P〈0.01). Night-time defecation (P=0.04) and use of antidiarrheals (P=0.04) were significantly lower for patients with a W-pouch. Maximum tolerated volume was greater in the W-pouch group throughout the whole period (P=0.01). Maximum resting anal pressure, maximum voluntary contraction, and rectoanal inhibitory reflex did not differ between the study arms CONCLUSION: Patients with W-pouch have better functional results than those with J-pouches in the “maturation period” after ileostomy closure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02235573
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  • 6
    Electronic Resource
    Electronic Resource
    Preperitoneal, minimally invasive, prosthetic groin hernia repair (2000)
    Springer
    Hernia 4 (2000), S. 316-320 
    Details
    ISSN: 1248-9204
    Keywords: Inguinal hernia ; Hernioplasty ; Preperitoneal approach ; Mesh ; Tension-free technique
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The study describes the advantages of using the positioning of the prosthesis in the pre-peritoneal space by a posterior approach in the repair of inguinal hernia. The research was carried out on 388 patients (372 (96%) men and 16 (4%) women), who had undergone hernioplasties with the insertion of a polypropylene prosthesis by a preperitoneal approach, between January 1994 and December 1996. 216 of these patients (56%) had an indirect inguinal hernia, 94 (24%) a direct inguinal hernia and 78 (20%) a double inguinal hernia (direct and indirect). In 21 cases (6%) it was a recurrent hernia. The following clinical parameters were considered: pain, sensitivity of the inguinal region, testicular pathology, wound pathology and recurrence. 384 patients out of 388 (99%) were discharged at latest one day after the operation. On average the patients went back to work 6 days after the operation. All the patients were checked at least three times out of four, with follow-ups at 30 days, 6 months, 1 year and 2 years after the operation. In 13 patients (1.8%) there was a minor complication, in 3 patients (0.8%) we found an early recurrence due to technical error. We consider that positioning the prosthesis in the preperitoneal space using this minimally invasive procedure can be carried out easily and with very good clinical results in terms of typical early and/or late complications, which range from 2% to 20% by the anterior approach.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01201093
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  • 7
    Electronic Resource
    Electronic Resource
    The different inhibiting effect of cholera toxin on two leukemia cell lines does not correlate with their toxin binding capacity (1995)
    Springer
    Molecular and cellular biochemistry 152 (1995), S. 103-112 
    Details
    ISSN: 1573-4919
    Keywords: WEHI-3B ; L1210 ; murine leukemia ; cholera toxin ; ganglioside ; toxin binding ; cAMP ; growth inhibition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The murine leukemia cell lines L1210 and WEHI-3B show a very different sensitivity to the cholera toxin (CT). Thein vitro growth of L1210 is completely inhibited by 10−8 M CT, while WEHI-3B growth shows the same inhibition at 10−11 M. The analysis of membrane ganglioside pattern of the two cell lines shows that in L1210 cells the major component is the GM1a ganglioside while the monosialoganglioside fraction from WEHI-3B is entirely composed of gangliosides of the ‘b’ series among which GM1b is the more represented. The total cholera toxin binding capacity of the ganglioside extract from L1210 cells is more than hundred fold higher than that of WEHI-3B and this difference is also confirmed by the number of CT receptors/cell and by the binding of FITC-B subunit of CT on the cells. These surprising data are in conflict with the poor sensitivity to CT evidenced by L1210 compared to WEHI-3B cells. In order to clarify this discrepancy we investigated the cAMP accumulation, the cell viability and the clonogenicity of these two leukemia cell lines following the treatment with CT and forskolin (FRSK). The treatment of WEHI-3B cells with CT induces a dramatic increase of intracellular cAMP which highly correlates with cell death and the decrease of clonogenicity and this result is partially obtained by the treatment with FRSK, L1210 cells do not evidence significant cAMP accumulation neither with CT nor with FRSK treatment. These data suggest that the different inhibiting effect of CT on WEHI-3B and L1210 cells does not correlate with their different pattern of gangliosides and the related toxin binding capacity. Further they indicate that the growth inhibition of WEHI-3B cells is closely related with a cAMP-dependent cell killing mechanism, while the inhibition of L1210 growth (produced by high concentration of CT) is mediated by a cAMP independent mechanism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01076072
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  • 8
    Electronic Resource
    Electronic Resource
    Sodium ion distribution in the vitreous body (1996)
    Springer
    Magnetic resonance materials in physics, biology and medicine 4 (1996), S. 241-245 
    Details
    ISSN: 1352-8661
    Keywords: vitreous body ; 23na nuclear magnetic resonance ; 23na relaxation times
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics
    Notes: Abstract We have studied the nuclear magnetic resonance (NMR) relaxation behavior, and thus the dynamic properties, of the sodium ion in the vitreous body at different temperatures. The23Na NMR spectrum exhibits a resonance, the intensity of which accounts for an ion visibility of 100%. The23Na longitudinal and transverse relaxation times, at all temperatures but the highest, present two components, suggesting that the sodium ions are present in two states of different mobility, whose populations are in slow exchange on the NMR time scale. The correlation times and quadrupole coupling constants for the two sodium pools have been derived. The faster relaxation of a fraction of the vitreal sodium has tentatively been ascribed to the influence of the macromolecular framework of the vitreous body. The reported information may be of use for the understanding of the diagnostic applications of23Na magnetic resonance imaging of the ocular structures.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01772012
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  • 9
    Electronic Resource
    Electronic Resource
    Low temperature thermal detectors in searches for rare events (1998)
    Springer
    Czechoslovak journal of physics 48 (1998), S. 133-144 
    Details
    ISSN: 1572-9486
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The role that low temperature thermal detectors are going to play in a few relevant subjects of Non Accelerator Physics is briefly reviewed. The use of large arrays of macrobolometers is considered in experiments on Solar Neutrinos, on Double Beta Decay, and on interactions of WIMPS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1021299321513
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  • 10
    Electronic Resource
    Electronic Resource
    1H NMR Ganglioside Ceramide Resonance Region on the Differential Diagnosis of Low and High Malignancy of Brain Gliomas (1997)
    Springer
    Cellular and molecular neurobiology 17 (1997), S. 521-535 
    Details
    ISSN: 1573-6830
    Keywords: brain gliomas ; ceramide ; ganglioside ; malignancy ; 1H NMR spectroscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract 1. The high-resolution 1H NMR (MRS) spectra of human brain tumor homogenates revealed a broad resonance at 5.3–5.4 ppm in glioblastoma multiforme (N = 16) and brain metastases (N = 2). The broad resonance was identified as ceramide, a sphingosine–fatty acid combination portion of ganglioside, indicating an elevated abundance of monounsaturated fatty acids. GLC analysis of gangliosides in the highly malignant glioblastoma multiforme revealed that the elevated monounsaturated fatty acid is oleic acid (C18:1). The resonance at 5.3–5.4 ppm region was not detectable in normal human brain (N = 2), in meningiomas (N = 2), or in low-grade astrocytomas (N = 12). In normal human brain the abundance of monounsaturated fatty acid is minimal. 2. This investigation was made possible because the method of producing homogenate resulted in (i) no loss of lipids during the process and (ii) a well-homogenised sample, with (iii) no loss in chemical integrity. 3. The properties of tumor gangliosides include antigenic specificity and immunosuppresive activity and the ceramide, a sphingosine–fatty acid combination, noticeably influences the ganglioside immunosuppressive activity. 4. The observation of 1H NMR ceramide resonance in high-malignant brain tumors emphasizes the dramatic role of aberrant gangliosides and ceramide precursors on the grade of malignancy and invasiveness. 5. Further insight into the specific nature of the ceramide portion of gangliosides in grading the malignancy of brain tumors should be investigated further.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1026362922549
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