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  • 1
    Electronic Resource
    Electronic Resource
    Copenhagen : Munksgaard International Publishers
    Experimental dermatology 10 (2001), S. 0 
    ISSN: 1600-0625
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Dendritic cells seem to be of major importance for the pathogenesis of psoriasis. They are increased in number in lesional psoriatic skin which is thought to be due to an increased influx from the peripheral blood regulated by chemotaxins. Using a biological/biochemical approach we have addressed the question whether psoriasis scale extracts contain proteinaceous chemotaxins for dendritic cells. Human monocytes differentiated into dendritic cells by culture with GM-CSF and IL-4 (MoDC) served as responder cells. Chemotactic activity for MoDC was purified by several HPLC-steps. The results of our study show that C5a/C5adesarg is the major chemotactic peptide for MoDC in psoriasis scale extracts. In comparison to other stimuli such as fMLP or monocyte chemotactic peptide 1 (MCP-1) C5a proved to be a most potent and efficient chemotaxin for MoDC. C5a co-eluted with MRP14/calgranulin B which is present in large amounts in psoriasis scale extracts as identified by amino acid sequencing. However, MRP14/calgranulin B did not possess any chemotactic activity for MoDC. Our results provide evidence that C5a/C5adesarg although not specific for dendritic cells seems to be the major chemoattractant for these cells in lesional psoriasis skin.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 467-470 (Oct. 2004), p. 537-544 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The recrystallization of a Zr-2Hf alloy sheet deformed by plane strain compression atroom temperature and then heat treated in the temperature range 500-650°C is studied. The microstructure, local and global crystallographic textures are investigated by EBSD and X-ray techniques. The as-deformed condition exhibits a heterogeneous microstructure composed of highly and less deformed zones, the EBSD indexing of the latter ones being more reliable. The asdeformed condition displays a (0001) 〈 0 1 10 〉 crystallographic texture. The evolution of themicrostructure during recrystallization very much depends on the amount of local deformation. Recrystallization begins in highly deformed zones, new grains having two variants of texture components, {0001} 〈 0 1 10 〉 and {0001} 〈 0 2 11 〉. Some change of preferred orientations concomitant with grain growth at 600 and 650°C has been observed with a decrease in the {0001} 〈 0 1 10 〉 component and an increase in the {0001} 〈 0 2 11 〉 component
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 70 (2000), S. 65-68 
    ISSN: 1432-0649
    Keywords: PACS: 42.65.Pc; 42.65.Hw; 42.50.Fx
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. The nonlinear optical (local) response of a dense collection of two-level atoms embedded in a linear dielectric medium is investigated theoretically. The nonlinear response of absorption and dispersion of two-level atoms associated with a weak probe field in the presence of a strong pump field is calculated in terms of the linear response theory. The numerical results show that the absorption and dispersion spectra are different from those in vacua because of the local-field effect enhancement and the local cooperative effect.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 35 (2000), S. 5609-5612 
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Ti-Al-Cu series burn-resistant alloys are newly developed materials which have low density, low cost and are easy to process. The results show that Ti-Al-Cu alloys have good burn resistance due to their good thermal conductivity, low melting point, and the existence of Ti2Cu phase which also has a very low melting point. Ti-Al-Cu alloys have excellent thermal processability and good room and high temperature tensile properties, but an increase in copper content harms their thermal stability. After thermal exposure for a long time, Ti2Cu phase will coalesce and coarsen, but the addition of Si and Al will be useful for their thermal stability. The Ti-13Cu-1Al-0.2Si alloy has good thermal stability at 540°C and good creep resistance at 300°C and 100 MPa. The phases of Ti-Al-Cu alloys were found to be composed of α phase and Ti2Cu. The character of the Ti2Cu phase changes with the increasing copper content.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 34 (1996), S. 1799-1805 
    ISSN: 0887-624X
    Keywords: ε-caprolactone and D,L-lactide copolymer ; random copolymerization ; rare earth coordination catalyst ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Highly random copolymers of ε-caprolactone (CL) and D,L-lactide (LA) were synthesized by a new catalyst system, rare earth chloride-propylene oxide (PO) system. In the presence of propylene oxide, all rare earth chlorides tested are highly effective for the copolymerization. The influences of reaction conditions on the copolymerization catalyzed by the NdCl3-5PO system have been investigated in detail. The reactivity ratios of ε-caprolactone and D,L-lactide were determined and show that the copolymerization with this new rare earth catalyst is closer to ideal copolymerization than reported for other catalysts. The microstructure of copolymer analyzed by 13C-NMR shows that the monomer units in the copolymer is near to completely random distribution with a short average monomer sequence length. The DSC measurement confirms the high randomness of the chain structure. The mechanism studied by NMR indicates that the rare earth alkoxide generated by the reaction of rare earth chloride with propylene oxide initiates the copolymerization, and then proceeds via a “coordination-insertion” mechanism with acyl-oxygen bond cleavage of CL and LA. © 1996 John Wiley & Sons, Inc.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Polymer International 41 (1996), S. 369-375 
    ISSN: 0959-8103
    Keywords: poly(1,3-trimethylene carbonate-co-glycolide) ; polymer surface biodegradation ; protein-controlled release matrix ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Poly(1,3-trimethylene carbonate-co-glycolide) (PGCA) has been synthesized by ring-opening polymerization of 1,3-trimethylene carbonate (CA) and glycolide (GA) with stannous octoate as catalyst. The copolymers were characterized by 1H nuclear magnetic resonance (NMR), 13C NMR and differential scanning calorimetry. Water content and static contact angle of distilled water on the polymer surface were used to evaluate the hydrophobicity of the copolymers. There was no apparent difference in hydrophobicities of copolymers containing up to 30 mol% GA. The biodegradation of PGCA was conducted in phosphate buffer solution at 37°C and in rats. The results indicated that the degradation rates of PGCA were higher than that of PCA and depended on the GA fraction in the copolymers. Furthermore, degradation occurred in the bulk when the GA content exceeded 20 mol%. With less GA units the degradation became a surface reaction both in vitro and in vivo. These properties of PGCA may be useful in protein delivery systems.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Polymer International 36 (1995), S. 293-297 
    ISSN: 0959-8103
    Keywords: poly(2-hydroxyethyl methacrylate)(PHEMA) ; poly(styrene-co-acrylamide)(PSAm) ; blend miscibility ; hydrogel membrane ; protein controlled release ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The blend miscibility of poly(2-hydroxyethyl methacrylate) (PHEMA) and poly(styrene-co-acrylamide) (PSAm) was studied by DSC. A ‘miscible window’ was found in the range 47-57 mol% of acrylamide in blending PSAm with PHEMA (1:1 w/w) and was analysed by the mean-field theory. The water content and permeability coefficients of proteins were measured. The results show that the water content of the blends depends on the composition of PSAm and the blends, and the behaviour of blends swollen in water in Fickian type. However, the permeability of the solutes not only related to water content, but was also affected by phase behaviour. Controlled release of somatotropin from a cylindrical device coated with PHEMA/PSAm was achieved.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 30 (2004), S. 117-121 
    ISSN: 1434-6079
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. The excitonic nonlinear optical responses due to exciton-phonon interactions in strongly coupled exciton-phonon systems are investigated theoretically. It is shown that the influence of exciton-phonon interactions on the nonlinear optical absorptions and Kerr nonlinear coefficients is significant as the signal field frequency detuning from the exciton frequency approaches to the optical phonon frequency. How to manipulate the nonlinear optical responses by using the control fields is also presented.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 31 (2004), S. 499-506 
    ISSN: 1434-6079
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. For two coupled identical quantum dots in a two-mode cavity, we determine the conditions of two-photon and single-photon resonance. It is shown that the exciton-phonon interaction reduces the Rabi frequencies of each model and the Förster interaction between double quantum dots even at absolute zero temperature. The exciton-phonon interaction also makes a contribution to the static exciton-exciton dipole interaction energy. Furthermore, the additional interactions can modify the conditions of photon resonance significantly. A more realistic case of two nonidentical quantum dots is also considered. The influence of parameter misfits on the quantum system is discussed.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Macromolecular Chemistry and Physics 196 (1995), S. 479-483 
    ISSN: 1022-1352
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The miscibility of poly(2-hydroxyethyl methacrylate)/poly(styrene-co-acrylamide) (PHEMA/PSAm) blends was investigated by nonradiative energy transfer fluorescence spectroscopy using anthracene-labeled PHEMA and carbazole-labeled PSAm. The results show that the ratio of the carbazole and anthracene emission intensity, Ic/Ia, passes through a minimum at 47 to 57 mol-% of acrylamide in PSAm copolymers in the blends, indicating that a ‘miscible window’ exists. It also was found that the results are consistent with those obtained by differential scanning calorimetry. The driving force for the miscibility of PHEMA/PSAm may be explained with a mean-field theory.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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