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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 60 (1989), S. 1951-1952 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A highly sensitive beam position monitor has been designed for use with synchrotron radiation sources. This beam position monitor consists of two gas-flow ionization chambers having three parallel plate conductors. The incident beam is divided by a central plate. Therefore, a displacement of the beam position is detected with the two outside ionization chambers. The position monitor was tested at the BL6Cl beamline of the Photon Factory (PF). The results show a good performance.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A 59-year-old Japanese man with myasthenia gravis, who had a 10-year history of temperature-sensitive pain in the lower extremities, i.e. improved by cooling and worsened by warming, consulted us because the pain had become intolerable during the previous 4 months. Bilateral erythema, swelling and large ulcers were noted on the calves, dorsal aspects of the feet, and soles. Laboratory data showed thrombocythaemia and a positive antibody to the acetylcholine receptor, but were negative for antinuclear and antiphospholipid antibodies. A diagnosis of secondary erythermalgia was made because of the clinical features, the laboratory data, and the lack of family history of this disease. Although steroid pulse therapy, oral aspirin and antiserotonin drugs were ineffective, bilateral lumbar sympathetic ganglion block succeeded in relieving the severe pain and curing the ulcers. The clinical course in our patient suggests that sympathetic ganglion block may be one of the most effective treatments for secondary erythermalgia. Although the mechanism of this effect is uncertain, microcirculation disturbance in secondary erythermalgia, if any, may be improved by this block.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 144 (2001), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 142 (2000), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 31 (2001), S. 0 
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Serum eosinophil cationic protein (ECP) levels reflect ongoing eosinophilic airway inflammation and are used as a marker for asthma activity. ECP levels, however, may not be elevated in some asthmatic patients, even when they are symptomatic.Objective To clarify the characteristics of patients with ‘low’ ECP titres despite asthma exacerbation.Methods Serum ECP levels were measured in 113 asthmatic patients during exacerbation. Patients were divided into two groups according to ECP titre: a high ECP group (H; ECP ≥ 16.0 µg/L) and a low ECP group (L; ECP 〈16.0 µg/L). Twenty-two patients who had recently received systemic steroids were excluded and the clinical features of the remaining patients in H (n = 54) and L (n = 37 were compared.Results Gender, atopic or smoking status, disease severity, inhaled steroid or theophylline usage, peak expiratory flow (% personal best) and forced expiratory volume in 1 s (FEV1) (% predicted) did not significantly differ between the two groups. Patients in L were significantly older and had longer disease duration and lower serum IgE levels than those in H. Multivariate analysis combining age, disease duration and IgE levels showed that age and disease duration were independently associated with ECP level. Airway wall thickness, assessed in a subset of patients using computed tomography, was significantly larger in L.Conclusion Serum ECP levels in asthmatic patients may not be elevated during exacerbation and thus may not be a useful marker in patients who are older, have longer disease duration or possibly have thicker airway walls. Mechanisms other than eosinophilic inflammation, such as airway remodelling, may be involved in asthma exacerbation in these patients.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 318 (1982), S. 340-343 
    ISSN: 1432-1912
    Keywords: Dog heart ; Ischemia ; Myocardial pH ; Sotalol ; Heart rate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In dogs anesthetized with pentobarbital, the left anterior descending coronary artery (LAD) was occluded partially so that the LAD flow could be reduced to 1/2 to 1/3 the original flow (partial occlusion). Myocardial pH was recorded continuously by the use of a micro glass pH electrode inserted in the area to become ischemic by partial occlusion. Before partial occlusion, myocardial pH was 7.51–7.66. Partial occlusion reduced the pH by 0.63–0.72. Sotalol (5 mg·kg−1, i.v.) increased the pH (by 0.45) that had been reduced by partial occlusion, with a marked decrease in heart rate (about 70 beats·min−1) and a slight decrease in blood pressure (about 10 mm Hg in systolic pressure). Even when the sotalol-induced decrease in heart rate was prevented by pacing the heart, sotalol (5 mg·kg−1, i.v.) increased the pH (by 0.43) of myocardium in which LAD was partially occluded. The pH of the non-ischemic normal heart, however, was not influenced by the injection of sotalol (5 mg·kg−1, i.v.) It is concluded that the effect of sotalol to increase the pH of the ischemic heart is not related to the decrease in heart rate produced by the drug injection.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Copenhagen : International Union of Crystallography (IUCr)
    Applied crystallography online 17 (1984), S. 470-475 
    ISSN: 1600-5767
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: A new curved linear position-sensitive detector has been developed and used in a computer-controlled high-speed data collection system with Weissenberg geometry for X-ray crystallography. This detector system enables one to see the entire Weissenberg diagram on a CRT display monitor in real time. A comparison between refinement results of the room-temperature phase of LiRbSO4 by this system and a conventional four-circle diffractometer showed that the atomic coordinates almost agree within the experimental errors. A new phenomenon was found with this system: LiRbSO4 changes into the twin state under external electric field at room temperature.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 312 (1984), S. 471-473 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Two-dimensional detectors of multiwire type8"10, despite their advantage over the one-dimensional detector, have not been applied to structural studies on muscle because the spatial resolution in the direction perpendicular to anode wires is limited. We have improved the resolution by the method11 ...
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-2013
    Keywords: K+ channels ; Acinar cells ; Ensemble noise analysis ; Current relaxation ; Patch-clamp whole cell recording
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The K+ channel in rat parotid gland acinar cells were investigated by ensemble current noise analysis in single isolated cells employing the giga-seal whole cell current recording mode. Sets of 20–40 identical de- and hyperpolarization voltage steps were applied and the resultant current records were processed by computer to obtain the mean and the variance of the current. The time-course of the mean current could be fitted by the sum of two exponentials, suggesting a 3-state model. The simplest plausible hypothesis is a model with one open and two closed states. Assuming this model, the relationship between the variance (σ2) and the mean current (I) could be fitted by the function σ2/I=i−I/N. The estimated single channeli/V-relations were similar to those taken from single channel current recordings, and the size of the population of channels per cell (N) was 76±26 (n=12). The validity of the model was tested by a successful simulation of the time-course of the variance.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1435-1536
    Keywords: Equilibrium dialysis ; hydrophobic interaction ; electrostatic interaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract In order to investigate the interactions of poly(2-diethylaminoethyl methacrylate) (PDEAEMA) with methyl orange and its homologs in solution, temperature dependence of the complex formation has been examined in detail by the measurements of transmittance and specific conductance for the systems. Furthermore, the binding course of dyes to PDEAEMA has been studied on the basis of thermodynamic parameters obtained from equilibrium dialysis experiments at different temperatures. It was observed that the flocculation process shifted to lower dye concentrations in accordance with increasing hydrophobicity of the dyes in the order, methyl orange 〈 ethyl orange 〈 butyl orange, and the process of complex formation was characterized by three separate regions according to the slope of specific conductivity-mixing ratio curve for mixtures of PDEAEMA and dye. The temperature dependences of ΔF,ΔH and ΔS suggest that, for dyes-PDEAEMA complex formation, the hydrophobic interaction is predominant at a low temperature but the electrostatic interaction becomes important as the temperature increases.
    Type of Medium: Electronic Resource
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