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  • 2000-2004  (1)
  • 1985-1989  (3)
  • 1960-1964
  • H, K-ATPase inhibitor  (2)
  • Binder of Rho GTPase  (1)
  • DACM staining  (1)
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  • 2000-2004  (1)
  • 1985-1989  (3)
  • 1960-1964
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    (+)-curcuphenol and dehydrocurcuphenol, novel sesquiterpenes which inhibit H,K-ATPase, from a marine spongeEpipolasis sp (1987)
    Springer
    Cellular and molecular life sciences 43 (1987), S. 1234-1235 
    Details
    ISSN: 1420-9071
    Keywords: Marine sponge ; Epipolasis ; curcuphenol ; H, K-ATPase inhibitor ; gastric secretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Two H, K-ATPase inhibitors and an inactive related compound have been isolated from a marine spongeEpipolasis sp. They are aromatic sesquiterpene α-curcumenes
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01945540
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Pathogenesis of pili annulati (1988)
    Springer
    Archives of dermatological research 280 (1988), S. 308-318 
    Details
    ISSN: 1432-069X
    Keywords: Pili annulati ; Ultrastructure ; DACM staining ; Hair cortex ; Protein metabolism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Plucked scalp hairs and hair roots of pili annulati were examined to understand their pathogenesis. Stereoscopic examinations of hairs in transmitted light and/or reflected light and light microscopic surveys of the cross-sections of hairs confirmed that the cortical empty spaces appeared to be responsible to the unique dotted shiny appearance of the hairs seen by the unaided eyes under a refracted light. By transmission electron microscope, small vacuoles and dense bodies were observed in the cytoplasm of the differentiating cortical cells; subsequently, with increasing number of tonofilaments, an uneven distribution of free ribosomes occurred and abnormal spaces containing fine granular substances were formed in the cytoplasm of the cortical cells. Occasionally, extremely large cortical trichohyaline granules were found. In the keratinized hair, irregular empty spaces were present in the cortex of the abnormal hair segments. Histochemically, the keratinized cortex of the affected hairs always had more residual SH groups than the controls. Pili annulati may be a disorder of protein metabolism involving a partial dysfunction of cytoplasmic ribosomes, resulting in a lack of cortical keratin formation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00440605
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Isolation of a hexaprenylhydroquinone sulfate from the marine spongeDysidea sp. as an H, K-ATPase inhibitor (1987)
    Springer
    Cellular and molecular life sciences 43 (1987), S. 1233-1234 
    Details
    ISSN: 1420-9071
    Keywords: Marine sponge ; Dysidea ; hexaprenylhydroquinone sulfate ; H, K-ATPase inhibitor ; gastric secretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A hexaprenylhydroquinone sulfate has been isolated as an H, K-ATPase inhibitor from a marine spongeDysidea sp. It also inhibited phospholipase A2 as well as secretion of gastric acid in rats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01945539
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Sequence analysis, gene expression, and chromosomal assignment of mouse Borg4 gene and its human orthologue (2000)
    Springer
    Journal of human genetics 45 (2000), S. 374-377 
    Details
    ISSN: 1435-232X
    Keywords: Key words Cell motility ; Binder of Rho GTPase ; CDC42 TC10 ; Borg4 ; Full-length cDNA ; Fluorescence in situ hybridization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The Borg (binder of Rho GTPases) family proteins interact with CDC42 and TC10 in a guanosine triphosphate (GTP)-dependent manner. We have isolated a full-length cDNA of the mouse Borg4 gene, which is a member of this family. Sequence analysis revealed that this gene encoded a putative 349-amino acid protein. By reverse transcription — coupled polymerase chain reaction (RT-PCR) analysis, we observed that Borg4 was expressed ubiquitously in adult tissues. Additionally, we determined the entire cDNA sequence of the putative human Borg4 orthologue. By fluorescence in situ hybridization, mouse Borg4 and the putative human orthologue have been assigned to mouse chromosome 11E and human chromosome 17q24–25, which has been described as syntenic to the mouse region.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100380070012
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    Paper (German National Licenses)
    Fulltext
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