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  • 1
    Electronic Resource
    Electronic Resource
    Presence of the Novel Pituitary Protein „7B2” in Bovine Chromaffin Granules: Possible Co-Release of 7B2 and Catecholamine as Induced by Nicotine (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 49 (1987), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We observed the presence of the novel pituitary protein „7B2” and its release in the bovine adrenal medulla. The 7B2 concentration (mean ± SEM) in extracts of the bovine adrenal medulla was 952 ± 155 pg/mg tissue (n = 6). 7B2 was distributed in the chromaffin granule fraction prepared from the bovine adrenal medulla and was released by high K+ and/or nicotine from cultured cells of the bovine adrenal medulla. Co-release of 7B2 with catecholamine induced by nicotine from the cultured bovine chromaffin cells was also observed. In an analysis of the bovine adrenal medulla chromaffin granule fraction on gel permeation chromatography, there was a major peak with an apparent molecular weight of 45,000, whereas a major peak with an apparent molecular weight of 20,000 was found in that on sodium dodecyl sulfate-polyacrylamide gel electrophoresis. On reverse-phase HPLC, a major peak with a retention time of 35 min was observed in the bovine chromaffin granule fraction and in the bovine anterior pituitary extract. These findings indicate that 7B2 is a secretory protein in the bovine adrenal medulla. The possibility that 7B2 might be released with catecholamine, possibly in response to stress, warrants investigation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1987.tb02440.x
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  • 2
    Electronic Resource
    Electronic Resource
    Microwave radiation by a relativistic electron beam propagation through low-pressure air (1985)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Fluids 28 (1985), S. 366-371 
    Details
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Intense relativistic electron beams fired into air at varying pressures display a wide range of microwave signatures. These experiments held beam current, energy, and pulse length constant while varying gas pressure. Our observing window is 10 to 40 GHz. At low pressures (〈10 mTorr) exponential spectra result, consistent with beam reflexing or virtual cathode oscillations. Above 20 mTorr the spectrum flattens and suggests collective emission at the beam-generated plasma frequencies. Power falls linearly with pressure above 20 mTorr, until electron-Neutral collisions damp the emission at a few Torr. However, weak 10 GHz emission appears at full atmospheric pressure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.865157
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  • 3
    Electronic Resource
    Electronic Resource
    Diagnosis of mildly relativistic electron velocity distributions by electron cyclotron emission in the Alcator C tokamak (1987)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Fluids 30 (1987), S. 3809-3820 
    Details
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Electron cyclotron emission from nonthermal electron distributions has been measured with a vertical view and control of multiple reflections. The observed intensities at the first few harmonics provide information that can be used to deduce the electron distribution function. Although harmonic overlap restricts the detail that can be obtained when the distribution is very energetic, a fitting procedure enables useful results to be obtained. The distribution functions during Ohmic runaway and lower-hybrid current drive and heating are presented. The current-drive distributions are not inconsistent with theoretical Fokker–Planck calculations, giving perpendicular and parallel "temperatures'' around 60 keV and 200 keV, respectively. The runaway cases have quite similar distributions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.866418
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  • 4
    Electronic Resource
    Electronic Resource
    Alcator C vertical viewing electron cyclotron emission diagnostic (1986)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 57 (1986), S. 1959-1961 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Electron cyclotron emission measured vertically through the center of a tokamak plasma yields detailed information about the electron velocity distribution. A diagnostic developed for this purpose on Alcator C tokamak uses specialized focusing optics to obtain a well-collimated viewing chord, a compact viewing dump made of Pyrex or Macor to reduce the effects of wall reflection and depolarization, and a rapid-scan polarizing Michelson interferometer InSb detector system for the spectrum measurement; all constrained by the limited access and the compact size of Alcator C. Results of diffraction analysis are used to evaluate the theoretical performance of the optical system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1138806
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  • 5
    Electronic Resource
    Electronic Resource
    Design and performance of compact vacuum-compatible submillimeter viewing dumps (1986)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 57 (1986), S. 1242-1247 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Compact, vacuum-compatible submillimeter viewing dumps, whose design parameters were based on the results of simple ray calculations, have been fabricated from Pyrex, Macor, and alumina. The measured performance of the dumps agrees qualitatively with calculated results. The absorption is somewhat lower than expected, but still acceptable (≥99% absorption for Pyrex and Macor). In an electron cyclotron plasma emission experiment on Alcator C tokamak, comparison of the emission spectra with and without the dump shows that the dump in this configuration is effective in suppressing the unwanted radiation by approximately 90%. The additional reflection is believed to be due to a portion of the antenna pattern missing the dump.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1138635
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  • 6
    Electronic Resource
    Electronic Resource
    Measurements of mildly relativistic electron distribution functions during lower hybrid heating and current drive (invited) (1986)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 57 (1986), S. 1951-1955 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Nonthermal electron distribution functions, arising during lower hybrid heating and current drive, have been measured on Alcator C tokamak using vertical electron cyclotron emission and also bremsstrahlung x-ray emission. The methods used for deconvolving the distribution from the radiation measurements are summarized and examples are given of results from different types of plasma, illustrating the present capabilities of the techniques. The cyclotron emission results are consistent with the x-ray analysis but provide additional information, particularly at lower energies (30–100 keV). The x rays are less ambiguous at high energy and give good forward/backward asymmetry diagnosis. The quality of information appears to be already adequate for a quantitative comparison with theory, but further experimental improvements seem possible.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1139194
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  • 7
    Electronic Resource
    Electronic Resource
    Evaluation of exciton absorption peak broadening factors in InGaAsP/InP multiple quantum wells (1988)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 53 (1988), S. 2290-2292 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We evaluated the magnitude of broadening factors of ground-state exciton absorption peaks in In1−xGaxAsyP1−y/InP (x=0.47y) multiple quantum wells (MQW's) with about 10 nm wells. The absorption peaks broadened with a decrease of y. Analyzing the absorption peak broadening with increasing temperature, the thermal broadening factor at 300 K was found to be about 9 meV and composition independent. Analyzing the photoluminescence linewidth at 4.2 K, it was found that composition fluctuations in the well caused an inhomogeneity of the exciton energy level of 4.4 meV for the y=1.0 MQW and 7.5 meV for the y=0.6 MQW, being the greatest contributors to inhomogeneous broadening. We conclude that the exciton absorption peak broadening with a decrease of y is primarily due to the increase of composition fluctuations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.100256
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  • 8
    Electronic Resource
    Electronic Resource
    Measurement of negative-ion density in high-density C4F8 plasma using a laser photodetachment technique combined with a millimeter-wave open resonator (2000)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 77 (2000), S. 495-497 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A technique for measuring negative-ion density in high-density plasmas used for materials processing has been developed; negative ions were detected by measuring the electron-density perturbation caused by laser photodetachment using a millimeter-wave open resonator. The measured negative-ion density for an inductively-coupled C4F8(5%–20%)/Ar plasma with electron densities around 1011 cm−3 at a pressure of 25 mTorr was comparable to the electron density. The results suggest that species produced via dissociation of C4F8 attaches electrons as effectively as C4F8. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.127022
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  • 9
    Electronic Resource
    Electronic Resource
    Circadian rhythm of melatonin and prostaglandin in modulation of stress-induced gastric mucosal lesions in rats (2002)
    Oxford UK : Blackwell Science Ltd.
    Alimentary pharmacology & therapeutics 16 (2002), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We previously demonstrated the circadian variation of water-immersion restraint stress (WRS)-induced gastric mucosal lesions in rats.〈section xml:id="abs1-2"〉〈title type="main"〉Aim:To investigate the roles of melatonin and prostaglandin in the gastric mucosa in circadian modulation of WRS.〈section xml:id="abs1-3"〉〈title type="main"〉Methods:Fasted rats were subjected to 4-h WRS during both the diurnal and nocturnal phases of a light/dark cycle. Mucosal lesions, serum melatonin concentrations, mucosal generation of prostaglandin E2 (PGE2) and mucosal gene expressions of cyclooxygenase (COX)-1 and -2 were evaluated.〈section xml:id="abs1-4"〉〈title type="main"〉Results:Lesion area after 4-h stress during the dark phase was significantly smaller than that in light-phase controls. Serum melatonin concentration in control rats during the light phase was significantly increased 4 h after WRS, but PGE2 generation was decreased by 48% as compared to that in intact mucosa before stress. In the dark phase, melatonin concentration after 4-h WRS was significantly depressed as compared with the control level at the corresponding time. PGE2 concentrations after 4-h WRS in the dark phase were not decreased compared with the control level at the corresponding time, although PGE2 level was significantly lower than that in light-phase controls. Expression of COX-1 and COX-2 mRNA was detected after exposure to stress in both the light and dark phases.〈section xml:id="abs1-5"〉〈title type="main"〉Conclusion:These results suggest that circadian rhythm has an important role in the formation of stress-induced gastric mucosal lesions in rats. The circadian rhythm of melatonin responses and PGE2 generation may contribute to nocturnal/diurnal rhythmicity of gastric mucosal defences between day and night.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.16.s2.11.x
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  • 10
    Electronic Resource
    Electronic Resource
    Increased gastric acid secretion after Helicobacter pylori eradication may be a factor for developing reflux oesophagitis (2001)
    Oxford UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 15 (2001), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The role of acid secretion in reflux oesophagitis which may develop after H. pylori eradication is not well known.〈section xml:id="abs1-2"〉〈title type="main"〉Aim:To investigate the participation of altered gastric acid secretion and the presence of hiatal hernia in the development of reflux oesophagitis after eradication therapy for H. pylori.〈section xml:id="abs1-3"〉〈title type="main"〉Subjects and Methods:A total of 105 patients with H. pylori infection, but without reflux oesophagitis at the time of eradication therapy, were followed prospectively for 7 months after the clearance of this microorganism. Gastric acid secretion was assessed by endoscopic gastrin test, and the presence of hiatal hernia by endoscopy.〈section xml:id="abs1-4"〉〈title type="main"〉Results:Reflux oesophagitis developed in 11 out of 105 (10.5%) patients when examined at 7 months after the eradication therapy. The incidence was correlated significantly with the increase in gastric acid secretion after the eradication of H. pylori, and was significantly higher in the patients with hiatal hernia (20%) than in those without it (0%).〈section xml:id="abs1-5"〉〈title type="main"〉Conclusions:Increased acid secretion after H. pylori eradication is an important risk factor of reflux oesophagitis, especially in patients with hiatal hernia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2001.00988.x
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