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  • 11
    Electronic Resource
    Electronic Resource
    Prognosis and work absence due to occupational contact dermatitis (2002)
    Oxford, UK : Munksgaard International Publishers
    Contact dermatitis 46 (2002), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The consequences of a diagnosis of occupational contact dermatitis (OCD) were investigated using cases available from the voluntary surveillance scheme, EPIDERM. Cases of OCD reported from November 1994 to September 1995 were identified and sampled to give at least 100 cases of allergic, irritant and mixed OCD reported by consultant dermatologists (344 cases) and occupational physicians (377 cases). A questionnaire was sent to the reporting physician to elicit further information. 512 completed questionnaires were returned, of which 510 were eligible for analysis. Among cases reported by dermatologists (n = 286) and occupational physicians (n = 224), 7% (6.3%) had been unemployed and 16.8% (20.1%) had taken sick leave. 3 factors independently predicted time off work in a logistic regression analysis: age OR = 1.25 (95% CI, 1.05–1.49), allergic dermatitis OR = 1.77 (95% CI, 1.13–2.79) and medicolegal assessment OR = 4.42 (95% CI, 2.20–8.89). Overall, 15.7% did not improve clinically between the first and last visit. Those who did not improve had been exposed to the agent for longer (mean 7.6 years) than those who did (5.3 years) (p = 0.09). In patients ≤ 45 years, those reported to be atopic failed to improve (25.4%) more often than those not atopic (13.4%) (p = 0.04). The substantial numbers (21%) with time off work and with persistent dermatitis suggest that OCD continues to have a significant impact on workers and their employers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0536.2002.460505.x
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  • 12
    Electronic Resource
    Electronic Resource
    Block and Graft Copolymers of Pivalolactone. I. A New Class of Elastoplastics and Thermoplastic Elastomers (1976)
    s.l. : American Chemical Society
    Macromolecules 9 (1976), S. 371-373 
    Details
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ma60050a042
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  • 13
    Electronic Resource
    Electronic Resource
    Convergence and Divergence in Development (1975)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Sociology 1 (1975), S. 223-246 
    Details
    ISSN: 0360-0572
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Sociology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.so.01.080175.001255
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  • 14
    Electronic Resource
    Electronic Resource
    Chemistry of the polynuclear metal halides. 13. Mixed-metal M6X12n+ species containing both tantalum and molybdenum (1978)
    s.l. : American Chemical Society
    Inorganic chemistry 17 (1978), S. 1867-1872 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic50185a034
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  • 15
    Electronic Resource
    Electronic Resource
    Rhinovirus infection up-regulates eotaxin and eotaxin-2 expression in bronchial epithelial cells (2001)
    Oxford, UK : Blackwell Science, Ltd
    Clinical & experimental allergy 31 (2001), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Human rhinoviruses (RVs) are the most common precipitants of asthma exacerbations. RV infection of bronchial epithelium results in local airway inflammation inducing eosinophil recruitment and activation. Induction of eosinophil chemoattractants could represent a central mechanism, as well as a prime target for intervention.Objective To assess the effect of RV infection on mRNA expression and production of eosinophil chemoattractants by bronchial epithelial cells in-vitro.Methods BEAS-2B cells were infected with major and minor RVs and the mRNA expression of IL-8, RANTES, MIP-1α, eotaxin, eotaxin-2, MCP-2, MCP-3 and MCP-4 was assessed by reverse transcription PCR. In cases where mRNA induction was observed, a fluoroimmunoassay was used to confirm protein production. To assess the virus-specificity of the observed reactions, cells were also exposed to inactivated RVs.Results RV infection was able to up-regulate mRNA expression of IL-8, RANTES, MIP-1α, eotaxin and eotaxin-2, did not affect MCP-4, while MCP-2 and MCP-3 were not expressed either at baseline or after virus infection. Protein production was confirmed for IL-8, RANTES and eotaxin, but not for MIP-1α. When RVs were inactivated cytokine up-regulation was almost completely lost.Conclusion Infection of bronchial epithelial cells with RVs results in the production of a wide array of mediators that are able to chemoattract eosinophils. These include the eosinophil-specific molecules eotaxin and eotaxin-2, in addition to IL-8 and RANTES, which are the most abundant. Eosinophil recruitment after RV infection of bronchial epithelium could represent a central event in the pathogenesis of virus-induced asthma exacerbations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2222.2001.01112.x
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  • 16
    Electronic Resource
    Electronic Resource
    The change from water to salt as the main vehicle for community-wide fluoride exposure in Basle, Switzerland (2003)
    Oxford, UK : Munksgaard International Publishers
    Community dentistry and oral epidemiology 31 (2003), S. 0 
    Details
    ISSN: 1600-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1600-0528.2003.00123.x
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  • 17
    Electronic Resource
    Electronic Resource
    Distribution of metals during digestion by cutthroat trout fed benthic invertebrates contaminated in the Clark Fork River, Montana and the Coeur d'Alene River, Idaho, U.S.A., and fed artificially contaminated Artemia (2000)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 56 (2000), S. 0 
    Details
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The concentrations of essential amino acids in three, undigested invertebrate diets collected from the Clark Fork River (CFR) for cutthroat trout were similar to each other, but were c. 25–75% less than Artemia that were exposed to a mixture of arsenic, copper, cadmium, lead and zinc in the laboratory. The Artemia diet appeared less palatable and the texture, quantity and appearance of the intestinal contents differed between fish fed the Artemia and CFR diets. The Pb% in the fluid fraction of the intestinal contents was greater for the Artemia (29%) than for the CFR diets (10–17%), and the Cu% in the amino acid plus metal fraction of the intestinal contents was greater for the Artemia (78%) than for two of the three CFR diets (67% and 70%). Intestinal contents of fish fed invertebrate diets collected from various sites on the Coeur d'Alene River (CDA), Idaho, were similar in texture, quantity, and appearance. For fish fed the CDA diets, differences in the distribution of metals among fractions of the digestive fluids appeared to be related to concentrations of metals in the invertebrate diets. Pb% was lowest of all metals in the fluid portion of the intestinal contents. However, 〉80% of all metals in the hind gut were associated with the particulate fraction where they may still be available for uptake through pinocytosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1095-8649.2000.tb02093.x
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  • 18
    Electronic Resource
    Electronic Resource
    An ultrastructural study of the effects of x-irradiation on the oral epithelium of the rat: Qualitative aspects (1976)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 5 (1976), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Adult male rats of Simonsen strain were given a dose of 5000 r at 50 peak KV of x-irradiation directed at the lower lip, which was everted through a hole in a lead rubber cylinder shielding the head and body of the animal. Light and electron microscopic observations were made on specimens of lip oral mucosa from animals killed at 2, 6, 26 and 50 h and at 12 days after irradiation. The experimental model met the aim of permitting the study of the sequential effects of a high dose of irradiation without causing ulceration of the mucosa.Widespread degenerative changes were noted in the basal cells as early as 2 h after x-irradiation, increasing in degree up to 50 h. They included inflation of the outer nuclear envelope and rough endoplasmic reticulum (RER) with loss of ribosomes, swelling of mitochondria and disarrangement of cristae evident at 2 h, followed at 6 h by swelling of nucleus and cytoplasm and 26 h by frank membrane breaks. Irreversible degrees of damage were noted in a small though growing minority of cells. Immediate mobilization of the Golgi-lysosomal system was evident as an increase in size of the zone, maximal at 2 h, and subsequent autophagic activity. Signs of recovery, beginning at 26 h, were noted in nuclear envelope, RER, intercellular space, and in mitotic activity by 50 h. Virtually complete recovery was seen at 12 days.It is held that the successful confinement of irradiation to a small tissue volume, the effective activity of the lysosomal system and the short epithelial turnover time were important factors in limiting the damage and in permitting recovery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1976.tb01766.x
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  • 19
    Electronic Resource
    Electronic Resource
    A fixed allele at microsatellite locus LS-39 exhibiting species-specificity for the black caviar producer Acipenser stellatus (2001)
    Oxford UK : Blackwell Science Ltd.
    Journal of applied ichthyology 17 (2001), S. 0 
    Details
    ISSN: 1439-0426
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: The sturgeon microsatellite LS-39 was amplified across 10 different species of Acipenserinae and exhibited the potential to identify the black caviar producer Acipenser stellatus on a genomic DNA level. This was because of a fixed allele of 111 bp, which was absent in the other species which were investigated. Concerning the source of sturgeon species, LS-39 is the first nuclear marker described to examine black caviar. Furthermore, new light is shed on the controversial ploidy state of sturgeons. The present authors findings at this microsatellite locus support the hypothesis that extant ~120 chromosomal species are modern diploids, whereas sturgeons with ~240 chromosomes should be considered as modern tetraploids.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1439-0426.2001.00234.x
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  • 20
    Electronic Resource
    Electronic Resource
    Evaluation of alternative alloys to precious ceramic alloys (1979)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 6 (1979), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In the first part of this study, the microstructures and the mechanical properties of precious, semi-precious, and nonprecious dental casting alloys for the porcelainbaked- to-metal technique have been determined. The semi-precious alloys contained only 50 % gold, and palladium, silver, and some base metals. The nonprecious alloys were of the nickel-chromium type. Discs and miniaturized tensile bars have been cast and tested either in the as cast condition, or after a simulation of the various porcelain bakes. Proof stress, ultimate tensile strength, elongation, and plastic stiffness have been measured and results compared by use of analyses of variance. The microstructure examination shows that the simulation of the porcelain bakes improves the homogeneity of the precious and semi-precious alloys. Simultaneously, the mechanical properties of the same alloys are also improved. One semi-precious alloy, still under development at the time of these tests, has its mechanical characteristics markedly dovv'ngraded by the thermal treatments. The nickel-chromium alloys exhibit the best range of mechanical properties for the porcelain-baked-to-metal technique, when considering the three most relevant properties: proof stress, plastic stiffness, and modulus of elasticity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2842.1979.tb01507.x
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