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  • 2000-2004  (1)
  • 1975-1979  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    INFLUENCE OF LIPIDS ON THE ACTIVITY OF CEREBROSIDE-SULPHOTRANSFERASE IN MOUSE BRAIN: A COMPARATIVE STUDY OF JIMPY AND NORMAL MOUSE BRAINS (1976)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 27 (1976), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— The effect of lipids other than the substrate cerebroside on the activity of cerebroside-sulphotransferase (CST) in Jimpy and normal mouse brain was investigated.The enzyme activity of an acetone-treated microsomal preparation can be stimulated in the presence of the extracted lipids either with or without addition of exogenous cerebroside as a substrate.The CST activity in the Jimpy mutant compared to that in normal animals differs from 18% in homogenate to approx 80% in solubilized or acetone-extracted microsomes.An addition of total lipid from normal mouse brain to microsomal preparations from which lipid has been removed by acetone results in a stimulation of Jimpy CST activity up to a value of 80% of normal mouse brain microsomes.Both Jimpy and normal mouse brain CST can be also stimulated by the addition of single lipid components such as cholesterol and lecithin by 50% in normal and 100% in Jimpy brain microsomes.These findings lead to the hypothesis that there is a lipid requirement for CST activity other than the substrate cerebroside.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1976.tb12288.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Phosphorylation of myelin basic protein by vaccinia virus cores (1976)
    [s.l.] : Nature Publishing Group
    Nature 263 (1976), S. 436-438 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Purified myelin basic protein was found to be an excellent substrate for the core-associated protein kinase (Figs 1 and 2a). No activator was needed, which suggests that myelin basic protein functions both as an activator and as a substrate4. The almost quantitative recovery of the radioactivity ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/263436a0
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Auto-antibody tests in peripheral neuropathies: pros and cons (2000)
    Springer
    Journal of neurology 247 (2000), S. 423-428 
    Details
    ISSN: 1432-1459
    Keywords: Key words Inflammatory neuropathies Antibodies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Most inflammatory neuropathies, both acute and chronic, probably result from an immune attack against antigens of the peripheral nervous system. Specific antibodies in serum that react with the peripheral nervous system have been described in a number of inflammatory neuropathies. We review the pathophysiological significance of auto-antibodies and discuss their use for the diagnosis of patients with peripheral neuropathy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004150070170
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    Paper (German National Licenses)
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