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  • 1995-1999  (2)
  • 1990-1994  (1)
  • 21.10.−k  (1)
  • In situ hybridization  (1)
  • Key words: Liver, MR—Liver neoplasms, MR—Liver neoplasms, diagnosis—Magnetic resonance (MR), contrast enhancement—Bile ducts, neoplasms.  (1)
  • 1
    Electronic Resource
    Electronic Resource
    MR imaging patterns of gadolinium retention within liver neoplasms (1998)
    Springer
    Abdominal imaging 23 (1998), S. 592-599 
    Details
    ISSN: 1432-0509
    Keywords: Key words: Liver, MR—Liver neoplasms, MR—Liver neoplasms, diagnosis—Magnetic resonance (MR), contrast enhancement—Bile ducts, neoplasms.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Background: To determine the spectrum of appearances of gadolinium retention within cholangiocarcinoma (CCA) and other liver neoplasms. Methods: Two hundred ten patients underwent hepatic magnetic resonance imaging (MRI) at 1.5 T with precontrast T1- and T2-weighted spin-echo (SE) images and delayed Gd-DTPA- or gadoteridol- (0.1 mmol/kg) enhanced T1-weighted SE images. Postcontrast images were evaluated for lesions suspicious for tumors, and lesion signal intensity was characterized as homogeneously or heterogeneously hypo-, iso-, mildly hyper-, or markedly hyperintense to liver. Data from 94 patients with benign or malignant neoplasms are presented. Results: Imaging demonstrated 237 malignant neoplasms (121 hepatocellular carcinoma [HCC], 26 CCA, 17 colon carcinoma metastases, 73 other tumors) and 28 benign neoplasms (22 hemangioma, six focal nodular hyperplasia [FNH]). One hundred forty malignant lesions appeared as homogeneous postcontrast (29 hypointense, 75 isointense, 17 mildly hyperintense, 19 markedly hyperintense) and 97 as heterogeneous (15 isointense, 50 mildly hyperintense, 32 markedly hyperintense). Malignant lesions showing homogeneous, mildly or markedly hyperintense signal intensity postcontrast included 10 CCA, seven HCC, six epithelioid hemangioendothelioma, eight neuroendocrine tumor metastases, three adenocarcinoma metastases of unknown origin, and one breast carcinoma metastasis. Hemangiomas appeared as homogeneous postcontrast in 19 lesions (six isointense, one mildly hyperintense, 12 markedly hyperintense) and as heterogeneous in three lesions (markedly hyperintense). FNH appeared as homogeneous postcontrast in one lesion (isointense) and as heterogeneous in five lesions (one isointense, four mildly hyperintense). Conclusion: Homogeneous gadolinium retention on delayed postcontrast images of malignant hepatic neoplasms is seen in a high percentage of CCA lesions and less commonly with other neoplasms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900410
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  • 2
    Electronic Resource
    Electronic Resource
    Abnormal cell divisions in leaf primordia caused by the expression of the rice homeobox geneOSH1 lead to altered morphology of leaves in transgenic tobacco (1996)
    Springer
    Molecular genetics and genomics 251 (1996), S. 13-22 
    Details
    ISSN: 1617-4623
    Keywords: Homeobox gene ; In situ hybridization ; Leaf morphology ; Transgenic tobacco
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Transgenic tobacco plants were generated carrying a rice homeobox gene,OSH1, controlled by the promoter of a gene encoding a tobacco pathogenesis-related protein (PR1a). These lines were morphologically abnormal, with wrinkled and/or lobed leaves. Histological analysis of shoot apex primordia indicated arrest of lateral leaf blade expansion, often resulting in asymmetric and anisotropic growth of leaf blades. Other notable abnormalities included abnormal or arrested development of leaf lateral veins. Interestingly,OSH1 expression was undetectable in mature leaves with the aberrant morphological features. Thus,OSH1 expression in mature leaves is not necessary for abnormal leaf development. Northern blot and in situ hybridization analyses indicate thatPR1a-OSH1 is expressed only in the shoot apical meristem and in very young leaf primordia. Therefore, the aberrant morphological features are an indirect consequence of ectopicOSH1 gene expression. The only abnormality observed in tissues expressing the transgene was periclinal (rather than anticlinal) division in mesophyll cells during leaf blade initiation. This generates thicker leaf blades and disrupts the mesophyll cell layers, from which vascular tissues differentiate. TheOSH1 product appears to affect the mechanism controlling the orientation of the plane of cell division, resulting in abnormal periclinal division of mesophyll cell, which in turn results in the gross morphological abnormalities observed in the transgenic lines.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02174339
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    High-spin isomeric state in144Pm (1993)
    Springer
    The European physical journal 345 (1993), S. 123-124 
    Details
    ISSN: 1434-601X
    Keywords: 21.10.−k ; 27.60. +j
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A new high-spin isomeric state with a half-life of ≥2μs was found in144Pm by observing the14N(136Xe,6n)144Pm reactions. The excitation energy and spin of the isomer were estimated to be ∼7.4 MeV and ∼27+, respectively. Filling gas in a recoil ion separator was used as the target material.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01290348
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    Paper (German National Licenses)
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