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  • 1995-1999  (2)
  • 1990-1994  (1)
  • insulin treatment  (2)
  • 65G10  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Effects of early insulin treatment on ultrastructural changes of glomeruli in diabetic rats revealed by the quick-freezing and deep-etching method (1996)
    Springer
    Diabetologia 39 (1996), S. 632-640 
    Details
    ISSN: 1432-0428
    Keywords: Quick-freezing ; deep-etching ; glomerulus ; insulin treatment ; streptozotocin-diabetic rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The three-dimensional ultrastructure of glomerular basement membrane (GBM) and mesangial matrix (MM) at an early stage of streptozotocin (STZ)-induced diabetes mellitus in rats was examined by the quick-freezing and deep-etching method. In diabetic rats, the GBM inner layer was diffusely enlarged and the meshwork structure not only in the GBM middle layer but also in the MM became markedly irregular due to the rupture of fine fibrils. This irregularity and enlargement of the mesh pores in diabetic rats developed during the experimental period and was significantly different from results in control rats. Insulin treatment from 1 week after STZ injection had significant effects in preventing the ultrastructural changes in the GBM and MM. It is suggested that early insulin treatment has significant effects in preventing size barrier disturbance of GBM and MM in STZ-induced diabetes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00418534
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Effects of early insulin treatment on ultrastructural changes of glomeruli in diabetic rats revealed by the quick-freezing and deep-etching method (1996)
    Springer
    Diabetologia 39 (1996), S. 632-640 
    Details
    ISSN: 1432-0428
    Keywords: Keywords Quick-freezing ; deep-etching ; glomerulus ; insulin treatment ; streptozotocin-diabetic rats.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The three-dimensional ultrastructure of glomerular basement membrane (GBM) and mesangial matrix (MM) at an early stage of streptozotocin(STZ)-induced diabetes mellitus in rats was examined by the quick-freezing and deep-etching method. In diabetic rats, the GBM inner layer was diffusely enlarged and the meshwork structure not only in the GBM middle layer but also in the MM became markedly irregular due to the rupture of fine fibrils. This irregularity and enlargement of the mesh pores in diabetic rats developed during the experimental period and was significantly different from results in control rats. Insulin treatment from 1 week after STZ injection had significant effects in preventing the ultrastructural changes in the GBM and MM. It is suggested that early insulin treatment has significant effects in preventing size barrier disturbance of GBM and MM in STZ-induced diabetes. [Diabetologia (1996) 39: 632–640]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00418534
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Multicriterion optimization using interval analysis (1990)
    Springer
    Computing 44 (1990), S. 47-57 
    Details
    ISSN: 1436-5057
    Keywords: 65G10 ; 65K10 ; Interval analysis ; multicriterion optimization ; multiobjective optimization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Zusammenfassung Bei der Bestimmung des globalen Optimums werden in der Vektoroptimierung intervallanalytische Methoden angewendet. Hier diskutieren wir Optimierungsprobleme, bei denen mehrere Zielfunktionen in Konfliktsituationen optimiert werden müssen.
    Notes: Abstract Interval Analysis methods have been applied for obtaining the global optimum of the multimodal multivariable functions. We discuss here the multicriterion optimization problem, where several objective functions must be optimized in conflicting situations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02247964
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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