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  • 1
    Electronic Resource
    Electronic Resource
    Characterisation of Human 5-Hydroxytryptamine2A and 5-Hydroxytryptamine2C Receptors Expressed in the Human Neuroblastoma Cell Line SH-SY5Y: Comparative Stimulation by Hallucinogenic Drugs (1996)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 67 (1996), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Stable transfection of the human neuroblastoma cell line SH-SY5Y with the human 5-hydroxytryptamine2A (5-HT2A) or 5-HT2C receptor cDNA produced cell lines demonstrating ligand affinities that correlated closely with those for the corresponding endogenous receptors in human frontal cortex and choroid plexus, respectively. Stimulation of the recombinant receptors by 5-HT induced phosphoinositide hydrolysis with higher potency but lower efficacy at the 5-HT2C receptor (pEC50 = 7.80 ± 0.06) compared with the 5-HT2A receptor (pEC50 = 7.30 ± 0.08). Activation of the 5-HT2A receptor caused a transient fourfold increase in intracellular Ca2+ concentration. Whole-cell recordings of cells clamped at −50 mV demonstrated a small inward current (2 pA) in response to 10 µM 5-HT for both receptors. There were no differences in potency or efficacy of phosphoinositide hydrolysis among four hallucinogenic [d-lysergic acid diethylamide (LSD), 1-(4-iodo-2,5-dimethoxyphenyl)-2-aminopropane (DOI), 5-methoxy-N,N-dimethyltryptamine, and mescaline] and three nonhallucinogenic drugs (m-chlorophenylpiperazine, quipazine, and ergotamine). Comparison of equipotent doses producing 20% of the maximal response induced by 5-HT revealed selective activation of the 5-HT2A receptor by LSD and to a lesser degree by DOI, mescaline, and ergotamine. Quipazine and 5-methoxy-N,N-dimethyltryptamine were relatively nonselective, whereas m-chlorophenylpiperazine selectively activated the 5-HT2C receptor. It is unlikely therefore that hallucinosis is mediated primarily by activity at the 5-HT2C receptor, whereas activity at the 5-HT2A receptor may represent an important but not unique mechanism associated with hallucinogenic drug action.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1471-4159.1996.67062521.x
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  • 2
    Electronic Resource
    Electronic Resource
    Electron paramagnetic resonance of erbium doped silicon (1996)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 69 (1996), S. 3854-3856 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Electron paramagnetic resonance measurements have been made on samples of float zone silicon, implanted with 1015 Er/cm2. One sample was coimplanted with oxygen to give an impurity concentration of 1020 O/cm3 and 1019 Er/cm3. In this coimplanted sample, sharp lines are observed which are identified as arising from a single spin 1/2 Er3+ center having a g tensor exhibiting monoclinic C1h symmetry. The principal g values and tilt angle are g1=0.80, g2=5.45, g3=12.60, and τ=2.6°. In the absence of O, the sharp lines are not observed. No Er3+ cubic centers were detected in either sample. Possible structures for the center are discussed. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.117127
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  • 3
    Electronic Resource
    Electronic Resource
    Economics of Knock Ratings of Otto-cycle Engine Fuels. (1922)
    s.l. : American Chemical Society
    Chemical reviews 22 (1922), S. 281-310 
    Details
    ISSN: 1520-6890
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/cr60071a010
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  • 4
    Electronic Resource
    Electronic Resource
    Vaginal Infections and Prematurity (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Birth 14 (1987), S. 0 
    Details
    ISSN: 1523-536X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: : This is a review of four vaginal and cervical infections that may be associated with prematurity, premature rupture of the membranes, or low birthweight. Urea-plasma urealyticum, group B streptococcus, Chlamydia trachomatis, and anaerobic vaginosis are discussed, along with other data regarding intrauterine infection as a cause of prematurity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1523-536X.1987.tb01460.x
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  • 5
    Electronic Resource
    Electronic Resource
    Primary Culture of Mouse Endometrium on Floating Collagen Gels: A Potential in Vitro Model for Implantation (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 476 (1986), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1986.tb20924.x
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  • 6
    Electronic Resource
    Electronic Resource
    Demography of a native strain of the melon fly, Dacus cucurbitae, from Hawaii (1985)
    Springer
    Entomologia experimentalis et applicata 38 (1985), S. 195-199 
    Details
    ISSN: 1570-7458
    Keywords: melon fly ; Dacus cucurbitae ; demography ; life tables ; host studies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Résumé Le développement préimaginal et les taux de survie d'une souche sauvage de D. cucurbitae de Hawaí sur six hôtes courants ont été examinés à 25°C. Ces résultats ont été combinés aux informations récoltées sur la survie des adultes, la fécondité et la fertilité pour réaliser des tables de vie. La durée du stade oeuf est légèrement supérieure à un jour pour cette espèce. La durée de développement de l'éclosion de l'oeuf à l'imago et les taux de survie ont été respectivement de 17 à 20 jours et de 35 à 85% suivant les hôtes. La fécondité brute (ponte totale) a été de 1293 oeufs par femelle, tandis qui ‘la fertilité’ (nombre total d'oeufs fertiles pondéré par les taux d'éclosion et de survie des adultes) était de 518 oeufs fertiles par femelle. Le taux d'accroissement (λ) variait de 1,08 à 1,12 suivant l'hôte sur lequel D. cucurbitae a été élevé. La proportion d'adultes dans une distribution en âge stable était d'environ 14% sur tous les hôtes.
    Notes: Abstract Preadult development and survival rates for a wild strain of melon fly in Hawaii were examined when reared on six common hosts at 25°C. These data were combined with information gathered on adult survival, fecundity and fertility in order to construct life tables. The duration of the egg stage was slightly over 1 day for this species. Depending on host, larval-to-adult development and survival rates were 17–20 days and 35–85%, respectively. Gross fecundity (total eggs) was 1293 eggs/♀ while net fertility (total fertile eggs weighted by hatch and adult survival) was 518 fertile eggs/♀. The finite rate of increase (λ) for the species was conditional on the host on which it was reared and ranged from 1.08 to 1.12. The percent of adults in the stable age distribution averaged around 14% over all hosts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00361932
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  • 7
    Electronic Resource
    Electronic Resource
    Reproductive limits and heterogeneity of male twospotted spider mites (1989)
    Springer
    Entomologia experimentalis et applicata 50 (1989), S. 209-214 
    Details
    ISSN: 1570-7458
    Keywords: Demography ; male population biology ; sex ratio ; Tetranychus urticae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Résumé La reproduction est un processus qui nécessite généralement un mâle et une femelle. Cependant la biologie des populations ne s'est traditionnellement intéressée qu'à la contribution des femelles dans ce processus. Un effet de cet accent sur les femelles est que l'activité reproductrice des mâles a été très ignorée. Cet article examine, dans un contexte démographique, l'activité reproductrice des mâles de T. urticae, acarien arrhénotoque et phytophage. Trois séquences de l'activité reproductrice des mâles ont été examinées: 1) la copulation, 2) l'insémination, 3) la reproduction. En moyenne un mâle de 1 jour a copulé 15 fois, inséminé 15 femelles et a eu 336 filles. Pendant les 8 premiers jours, le mâle moyen a inséminé 70 femelles et a eu 1145 filles. Ces résultats suggèrent que le nombre de spermatozoïdes transférés à chaque insémination, plus que le nombre d'inséminations, est le facteur limitant d'une forte contribution du mâle à la reproduction.
    Notes: Abstract This paper determines reproductive limits and variation in performance of male twospotted spider mites Tetranychus urticae Koch when virgin females are provided ad libitum over the first eight days of adult life. Theree phases of male reproduction were studied: copulations, insemination and reproduction. An average one day old male copulated 15 times, inseminated 15 females, and contributed to 336 daughters. All parameters declined with age. The average male inseminated 70 females and contributed to 1145 daughters in the first days. Variability between males was small for all parameters considered. These data suggest that the number of sperm transferred at each insemination, rather than the number of inseminations, is the limiting step to higher male reproductive output.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00341169
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  • 8
    Electronic Resource
    Electronic Resource
    Life history response of female Mediterranean fruit flies, Ceratitis capitata, to periods of host deprivation (1986)
    Springer
    Entomologia experimentalis et applicata 42 (1986), S. 159-167 
    Details
    ISSN: 1570-7458
    Keywords: Mediterranean fruit fly ; Ceratitis capitata ; host deprivation ; senescence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Résumé Les femelles de C. capitata ont été privées d'hôtes suivant 4 modalités pendant 3 durées (33, 50 et 67% de leur vie) par période de 24 heures. Les modalités se répartissaient de la privation pendant 8 jours après l'éclosion jusqu'à 1 jour sur 3. La survie a été notée chaque jour et la ponte pour tous les jours où il y avait des hôtes. L'effect direct de l'absence d'hôte est d'empêcher la femelle de pondre. Ceci interrompt leur cycle de ponte et réduit leur activité reproductrice totale. Un effort reproductif réduit des femelles jeunes augmente la survie (jusqu'à 2 fois) et la ponte quotidienne (jusqu'à 8 fois) chez les femelles plus âgées. Ainsi, l'effet à long terme de la privation d'hôtes est d'ajourner la sénescence. Les implications de ces observations sur la sénescence de C. capitata sont discutées quant à: (1) la réduction des taux d'extinction des populations pendant les périodes de rareté d'hôtes; et: (2) les stratégies d'obtention de pontes dan les élevages de masse de C. capitata.
    Notes: Abstract Female medflies were subjected to four different patterns of host deprivation at each of three levels for a 24-day period. Treatments ranged from host absence 8 days post-eclosion to host absence 2 out of 3 days. Survival was recorded daily and egg production was recorded on the days in which hosts were present. The direct effect of host deprivation is to deny females the opportunity to oviposit. This disrupts their reproductive cycle and reduces their overall reproductive effort. Reduced reproductive effort at young ages increases survival (up to 2-fold) and daily reproduction (up to 8-fold) at older ages. Therefore, the long term effect of host deprivation is to postpone senescence. The implications of these findings regarding medfly sensescence are discussed in relation to: (i) reduction in population extinction rates during periods of host scarcity and (ii) egging strategies in medfly mass-rearing.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00343543
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  • 9
    Electronic Resource
    Electronic Resource
    Age and host effects on clutch size in the Mexican fruit fly, Anastrepha ludens (1988)
    Springer
    Entomologia experimentalis et applicata 47 (1988), S. 73-80 
    Details
    ISSN: 1570-7458
    Keywords: Tephritidae ; Mexican fruit fly ; Anastrepha ludens ; clutch size ; host selection ; insect demography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Résumé L'examen a porté sur l'influence du polymorphisme et des modifications dues à l'âge des mouches sur la fécondité et la taille des pontes de A. ludens Loew (Dipt. Tephritidae). L'étude a concerné aussi l'influence de la dimension, de la couleur et de la densité des hôtes sur la taille des pontes. Des mouches isolées ou par groupes ont reçu des hôtes artificiels formés de sphères d'agar enveloppées dans du parafilm. La fécondité brute de femelles isolées a été de 1000 oeufs/femelle et de 165 pontes/femelle, avec une variation de 1 à 40 oeufs/ponte. La taille moyenne des pontes des différentes femelles isolées s'étalait de 4,5 à 10,6 oeufs/ponte. Le nombre d'oeufs/ponte des femelles groupées était fortement liée à la dimension de l'hôte, s'étalant de 4,4 oeufs/ponte pour des hôtes de 2 cm de diamètre à 12,7 oeufs/ponte pour ceux de 11 cm de diamètre. Ni la couleur et la densité des hôtes, ni la densité et l'âge des mouches n'ont influé sur la taille des pontes. Ces résultats suggèrent que les variabilités du comportement des femelles et de la dimension des hôtes déterminent par priorité la taille des pontes de A. ludens.
    Notes: Abstract We document individual and age-specific variation in reproductive output and clutch size of Anastrepha ludens Loew. (Diptera: Tephritidae). The influence of host size, color, and density on clutch size are also examined. Individual and groups of flies were offered artificial hosts composed of agar spheres wrapped in Parafilm. The gross reproduction rate of individual flies was 1000 eggs/female and 165 clutches/female with a range of 1 to 40 eggs/clutch. Mean clutch sizes for these females ranged from 4.5 to 10.6 eggs/clutch. The number of eggs/clutch laid by females held in groups was highly correlated with host size, ranging from about 4.4 eggs/clutch in 2 cm diameter hosts to 12.7 eggs/clutch in 11 cm hosts. Host color, host density, fly density, and fly age did not affect clutch size. This study suggests that variation among females and host size are the principal determinants of clutch size in A. ludens.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00186718
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  • 10
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    Positive and Negative Experiences of Hospitalized Adolescents (1988)
    Roslyn Heights, N.Y. : Periodicals Archive Online (PAO)
    Adolescence. 23:89 (1988:Spring) 115 
    Details
    ISSN: 0001-8449
    Topics: Education , Psychology
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:c010-1988-023-89-000013
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