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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 94 (1988), S. 88-92 
    ISSN: 0942-0940
    Keywords: Stereotaxy ; brain tumour ; combined open-stereotaxic procedure ; instrumentation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The combined use of Stereotaxic and microsurgical techniques makes it possible to minimize damage to critical nervous tissue during operations in subcortical regions. The Riechert Stereotaxic system has been further modified. The patient's head is fixed in the new head ring with standard Mayfield pins. The headring is connected to a standard Mayfield clamp at symmetrical bearings at 0, 90, 180, and 270 degrees, which holds the head stable in any desired position and allows unhindered access to the cranial vault and skull base.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 83 (1986), S. 12-19 
    ISSN: 0942-0940
    Keywords: Intracerebral midline cysts ; cavum vergae ; developmental cystic malformations ; hydrocephalus ; stereotactic surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cavum vergae cysts (CVC) are cerebral midline malformations, which usually have no clinical manifestations. In rare cases, however, non-communicating cysts can cause hydrocephalus by obstruction of the aqueduct. Initially, from 1930 to 1960 operative treatment consisted in open cysto-ventriculostomy,i.e. establishing a communication between CVC and the ventricles, via a transventricular approach. In the era of CT, symptomatic treatment of the hydrocephalus by ventriculo-atrial or ventriculo-peritoneal sunts is preferred. All the wellknown complications of shunting are encountered. Based on the experience of our cases of CVC with clinical manifestations, we here propose a definitive causal treatment which can be achieved by draining the cyst contents into the ventricles via a stereotactically introduced catheter.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 83 (1986), S. 24-30 
    ISSN: 0942-0940
    Keywords: Colloid cysts ; hydrocephalus ; stereotactic puncture ; third ventricle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Colloid cysts of the third ventricle can cause hydrocephalus if they grow to the point where they occlude the foramina interventricularia. The operative approach via a craniotomy used to be the common method of treating these lesions. Now, in the era of CT- and MR-scanning, stereotactic aspiration should be preferred as an ideal method of simultaneously diagnosing and treating colloid cysts. Unlike open surgery, aspiration of colloid masses poses hardly any risk for the patient. Ten cases successfully treated by this technique are presented.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0942-0940
    Keywords: Proliferating cells ; Ki-67 ; brain tumour ; stereotactic biopsy ; tumour grading
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The monoclonal antibody Ki-67 has been tested as a marker of proliferating cells in 52 stereotactic brain tumour biopsies. The antibody reacts with a nuclear protein expressed in G1,S, G2n and Mphases of the cell cycle. Using the immunoperoxidase technique on squash preparations the percentage of Ki-67 positive cells was determined as a fraction of the total number of tumour cells present. This Ki-67 index was in close correlation with the histological grade. Highest values were found in a pineal germinoma (46.3%) and in 3 primary cerebral non-Hodgkin lymphomas (mean 39.5%). Among the gliomas, the highest fraction of proliferating cells was seen in 2 anaplastic paediatric brain stem gliomas (mean 17.4%) and in an anaplastic ependymoma (12.5%). Anaplastic astrocytomas and glioblastomas varied considerably with mean values of 9.5% and 8%, respectively. To some extent this variability may reflect tumour heterogeneity which is more likely to manifest in small stereotactic samples than in large tissue specimens obtained during open surgery. Pilocytic astrocytomas, mixed gliomas and fibrillary astrocytomas had moderate to low percentages. Ki-67 staining of squash preparations can easily be performed on a rountine basis and is, in our experience, superior to frozen sections. This method allows the determination of the growth fraction of an individual tumour and could become an important additional criterion for the decision among alternative and potentially harmful therapeutic regimens.
    Type of Medium: Electronic Resource
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