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  • 1
    Electronic Resource
    Electronic Resource
    Acidic fibroblast growth factor (aFGF) is present in the fluid of brain tumour pseudocysts (1990)
    Springer
    Acta neurochirurgica 107 (1990), S. 88-92 
    Details
    ISSN: 0942-0940
    Keywords: Fibroblast growth factor ; brain tumour cysts ; glioma neovascularization ; endothelial cell proliferation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fluid samples from brain tumour pseudocysts were examined for the presence of Fibroblast Growth Factor (FGF). Fluids were collected from 6 patients with differentiated low grade gliomas (group A), 3 anaplastic gliomas (group B) and 3 metastases (group C). For FGF assays pooled fluids from group A, B, and C were subjected to affinity chromatography on a Heparin-Sepharose column. Each pool contained endothelial cell mitogenic activity which eluted in the 1.2 M NaCl fraction and to a lesser degree in the 0.6 M fraction of Heparin-Sepharose high affinity chromatography. Mitogenic activity in the 1.2 M NaCl fraction of Heparin-Sepharose chromatography suggests the presence of acidic FGF (aFGF).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01405785
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  • 2
    Electronic Resource
    Electronic Resource
    Experimental radiofrequency (RF) coagulation with computer-based on line monitoring of temperature and power (1989)
    Springer
    Acta neurochirurgica 96 (1989), S. 126-131 
    Details
    ISSN: 0942-0940
    Keywords: Thermocoagulation ; radiofrequency lesioning ; real time monitoring ; computer-based monitoring
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The safety and reliability of radiofrequency coagulative techniques are questioned after each coagulation, especially in functional neurosurgery. In spite of the high level of technical development of modern surgical RF generators there is still uncertainty about the character of the coagulative lesion. For the present study, a 500 kHz RF generator was connected through a module for analog/digital conversion and for regulation to a personal computer provided with a software programme for the graphic display in real time of the RF power and of the temperature/time curves. The effects of thermocoagulation were studied in fresh egg white, and monopolar lesions were made in the subcortical white matter of rabbits with a probe with a 0.5 mm diameter and a bare tip of 3 mm in length. The regularity of thermocoagulation depends on the accurate temperature reading at the tip of the electrode. The ideal course of the temperature is a smoothly ascending curve from the level of 37 °C to the level present for coagulation, followed by a straight horizontal line. With too slow a response of the probe to temperature changes there is an inherent danger of overheating in the initial phase of the procedure. Additionally the power level has to be adjusted for each probe. On line monitoring with graphic display of the physical parameters provides a direct control of the course of the coagulation. Regular curves of the physical parameters without temperature overshoot correspond to reproducible lesionsin vitro andin vivo.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01456171
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  • 3
    Electronic Resource
    Electronic Resource
    Clinical value of percutaneous needle trephination (PNT) (1980)
    Springer
    Acta neurochirurgica 54 (1980), S. 181-189 
    Details
    ISSN: 0942-0940
    Keywords: Percutaneous needle trephination ; twist drill trephination ; CSF ; hydrocephalus ; ICP monitoring
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 56 neurosurgical patients 70 percutaneous needle trephinations were performed. This method was mostly used in patients with acute increase of ICP due to occlusive hydrocephalus of various aetiologies. Thanks to the accuracy and exhaustiveness of CT information, and thanks to the simplicity and safety of percutaneous needle trephination, this latter could be more and more used in daily clinical practice as a diagnostic and therapeutic procedure, for example for the study of adult hydrocephalus, for provisional external ventricular drainage, for treatment of CSF infections, and for ventricular bleedings (also in newborns and premature infants). No serious complication was seen even after prolonged CSF drainage over a period of 41 days. The method of PNT, as described in detail, can be used under sterile conditions at the bedside, on the stretcher in the emergency room, or in the CT or X-ray laboratory. It fulfils the criteria for clinical acceptance: simplicity, low risk, reliability, exactness, and effectiveness.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01407084
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  • 4
    Electronic Resource
    Electronic Resource
    Colloid cysts of the third ventricle (1986)
    Springer
    Acta neurochirurgica 83 (1986), S. 24-30 
    Details
    ISSN: 0942-0940
    Keywords: Colloid cysts ; hydrocephalus ; stereotactic puncture ; third ventricle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Colloid cysts of the third ventricle can cause hydrocephalus if they grow to the point where they occlude the foramina interventricularia. The operative approach via a craniotomy used to be the common method of treating these lesions. Now, in the era of CT- and MR-scanning, stereotactic aspiration should be preferred as an ideal method of simultaneously diagnosing and treating colloid cysts. Unlike open surgery, aspiration of colloid masses poses hardly any risk for the patient. Ten cases successfully treated by this technique are presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01420504
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  • 5
    Electronic Resource
    Electronic Resource
    Cerebral angiography under stereotactic conditions (1988)
    Springer
    Acta neurochirurgica 91 (1988), S. 147-150 
    Details
    ISSN: 0942-0940
    Keywords: Stereotaxy ; cerebral angiography ; brain tumour biopsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A simple system for cerebral angiography under stereotactic conditions using standard components is described. X-ray tubes and power generator belong to the usual equipment of the stereotact operating room. A film changer and an injection pump were integrated into the stereotactic arrangement. Angiographic documents with reduced X-ray magnification were obtained. For topographical orientation 5 films per seriogram were sufficient. The system also allows stereoscopic viewing by performing an additional oblique sequence after the head ring is rotated exactly 6 degrees. The combination of the necessary diagnostic procedures, as CT scan, angiography, ventriculography, serial biopsy within a single three coordinate reference system offers considerable advantages for brain tumour patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01424573
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  • 6
    Electronic Resource
    Electronic Resource
    Cavum vergae cyst as a cause of hydrocephalus, “Almost Forgotten”? (1986)
    Springer
    Acta neurochirurgica 83 (1986), S. 12-19 
    Details
    ISSN: 0942-0940
    Keywords: Intracerebral midline cysts ; cavum vergae ; developmental cystic malformations ; hydrocephalus ; stereotactic surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cavum vergae cysts (CVC) are cerebral midline malformations, which usually have no clinical manifestations. In rare cases, however, non-communicating cysts can cause hydrocephalus by obstruction of the aqueduct. Initially, from 1930 to 1960 operative treatment consisted in open cysto-ventriculostomy,i.e. establishing a communication between CVC and the ventricles, via a transventricular approach. In the era of CT, symptomatic treatment of the hydrocephalus by ventriculo-atrial or ventriculo-peritoneal sunts is preferred. All the wellknown complications of shunting are encountered. Based on the experience of our cases of CVC with clinical manifestations, we here propose a definitive causal treatment which can be achieved by draining the cyst contents into the ventricles via a stereotactically introduced catheter.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01420502
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  • 7
    Electronic Resource
    Electronic Resource
    Real-time ultrasound imaging of cerebral lesions during “target point” stereotactic procedures through a burr hole (1995)
    Springer
    Acta neurochirurgica 132 (1995), S. 134-137 
    Details
    ISSN: 0942-0940
    Keywords: Stereotaxy ; peroperative ultrasound imaging ; real-time stereotactic ultrasound
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Stereotactic burr-hole procedures like biopsies of brain tumours based on CT scan or MRI and angiographic data have so far usually been carried out without real-time ultrasound image control. Intra-operative real-time ultrasound imaging was carried out during twelve target-point stereotactic procedures via a single standard burr-hole using a new slender ultrasound transducer with a diameter of 8 mm. The technical parameters of the transducer are: frequency range of 5 〈−〉 3.5 MHZ, phased array sector scan, 90 degree sector. The transducer has a bayonet-like configuration and can be sterilized. Sufficient quality of the images was achieved in these twelve cases with different pathological entities such as malformation cysts (3 cases), gliomas (7 cases), one metastasis and one intracerebellar haemorrhage. Moreover, co-ordinate values may be calculated from the ultrasound images generated peroperatively, allowing the surgeon to choose additional targets. Colour flow mapping provides the visualization of vascular structures. For the beginner stereotaxy may be easier to learn using ultrasound real-time imaging.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01404861
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  • 8
    Electronic Resource
    Electronic Resource
    Needle fixing device for percutaneous needle trephination (1981)
    Springer
    Acta neurochirurgica 58 (1981), S. 131-133 
    Details
    ISSN: 0942-0940
    Keywords: Needle fixing device ; percutaneous needle trephination ; CSF ; ICP monitoring ; hydrocephalus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The author describes a device for the fixation of the needle, instead of plaster, in percutaneous needle trephination (PNT) for continuous measurement of ventricular ICP or for external ventricular drainage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401692
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  • 9
    Electronic Resource
    Electronic Resource
    Arachnoidalzyste als Ursache eines Hypernatriämie-Hypodypsie-Syndroms (1998)
    Springer
    Monatsschrift Kinderheilkunde 146 (1998), S. 603-607 
    Details
    ISSN: 1433-0474
    Keywords: Schlüsselwörter Hypernatriämie ; Hypernatriämie-Hypodypsie-Syndrom ; Arachnoidalzyste ; Stereotaxie ; Kinder ; Key words Hypernatremia ; Hypodipsic-hypernatremia-syndrome ; Arachnoid cyst ; Stereotactic surgery ; Children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Background: In rare cases a hypernatremia is caused by cerebral dysregulation. Case: We describe a 3,5 year old girl who had a hypodipsic-hypernatremia-syndrome (serum sodium concentration 194 mmol/l) caused by an arachnoid cyst in front of the pons. Therapy: In a stereotactic puncture a catheter was implanted. Aspiration of the cyst liquid did reduce the size of the cyst. For two years now no other treatment is given. Hypernatremia did not occur again. Discussion: To our knowledge this is the first case of a hypodipsic-hypernatremia-syndrome caused by an arachnoid cyst, which was cured by a single operation.
    Notes: Zusammenfassung Hintergrund: In seltenen Fällen werden Hypernatriämien durch zerebrale Regulationsstörungen verursacht. Fall: Wir berichten von einem 3,5 Jahre alten Mädchen, bei dem ein Hypernatriämie-Hypodypsie-Syndrom (Serumnatrium 194 mmol/l) durch eine präpontine Arachnoidalzyste verursacht wurde. Therapie: Durch eine stereotaktische Operation wurde ein Katheter implantiert. Der Zysteninhalt wurde aspiriert und die Zyste dadurch verkleinert. Seit 2 Jahren trat ohne medikamentöse Therapie keine Hypernatriämie mehr auf. Diskussion: In diesem Fall konnte nach unserem Wissen erstmals ein Hypernatriämie-Hypodypsie- Syndrom, das durch eine Arachnoidalzyste verursacht wurde, durch eine Operation geheilt werden.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001120050300
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  • 10
    Electronic Resource
    Electronic Resource
    CT-Angiographie in der Planung stereotaktischer Biopsien (1996)
    Springer
    Der Radiologe 36 (1996), S. 867-871 
    Details
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Computertomographie ; Spiral-CT ; Zerebrale CT-Angiographie ; Stereotaktische Biopsie ; Key words Computed tomography ; Helical CT ; Cerebral CT angiography ; Stereotactic biopsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Twenty-one patients referred for stereotactic biopsy were studied by CT angiography. Helical CT with 1 mm collimation was obtained (pitch of 1 : 1). Multiplanar reconstructions were performed; maximum intensity projections and shaded-surface displays were generated by connectivity-based editing tools. The visualization of cerebral vessels was excellent. No further conventional angiography was needed. Improved information was obtained about localization of the intracranial lesion and its relationship to neighboring vessels. No bleeding complications were detected by CT after stereotactic biopsy.
    Notes: Zusammenfassung 21 Patienten wurden in Zusammenhang mit einer stereotaktischen Biopsie CT-angiographisch untersucht. Dazu wurde eine Dünnschicht-Spiral-CT mit einer Kollimatorschichtdicke von 1 mm (Tischvorschub 1 : 1) durchgeführt. Es wurden multiplanare Rekonstruktionen sowie mit semiautomatischen Verfahren Maximumintensitätsprojektionen (MIP) und 3D-Oberflächendarstellungen (SSD) angefertigt. Die Darstellung der zerebralen Gefäße war so detailreich, daß in allen Fällen auf eine konventionelle Hirnangiographie verzichtet werden konnte. Zusätzlich ergaben sich wertvolle Informationen über Lokalisation und Ausdehnung der Läsionen sowie über die Beziehungen zwischen Tumor und Gefäßen. In der Kontroll-CT nach der Biopsie fanden sich in keinem Fall Blutungskomplikationen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001170050153
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