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  • 1
    Electronic Resource
    Electronic Resource
    Macroscopic study of the adult thymus (1987)
    Springer
    Surgical and radiologic anatomy 9 (1987), S. 51-62 
    Details
    ISSN: 1279-8517
    Keywords: Macroscopic anatomy of the thymus ; Anatomy of the parathyroid glands ; Thymic compartment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé La dissection de 48 pièces cadavériques, confrontée à des données opératoires, permet de rappeler la forme, la taille et la situation de cette glande chez l'adulte. La constitution de la loge thymique puis les rapports du thymus avec, en particulier, les vaisseaux du médiastin supérieur et la base du cou sont étudiés. Les positions respectives des glandes parathyroïdes inférieures et du thymus avec l'incidence de cette topographie dans la chirurgie de ces glandes, sont précisées. La vascularisation artérielle de la glande, encore très riche chez l'adulte est en faveur d'un organe fonctionnel dont l'involution physiologique est lente.
    Notes: Summary The dissection of. 48 cadaveric specimens has been compared with operative findings for a review of the shape, size and site of this gland in the adult. The structure of the thymic compartment and the relations of the thymus, particularly with the vessels of the superior mediastinum and the base of the neck, were studied. The relative positions of the inferior parathyroid glands and the thymus were identified, with respect to the influence of this topography on the surgery of these glands. The arterial suply to the thymus, which is still very abundant in the adult, presupposes a functional organ whose physiologic involution is slow.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02116854
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  • 2
    Electronic Resource
    Electronic Resource
    Left subpancreatic transplexus exposure of the proximal abdominal aorta (1996)
    Springer
    Surgical and radiologic anatomy 18 (1996), S. 167-172 
    Details
    ISSN: 1279-8517
    Keywords: Celiac axis ; Superior mesenteric artery ; Celiac plexus ; Multiorgan procurement
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les auteurs rapportent leur expérience basée sur l'étude anatomique de la région coeliaque de Luschka et sur la pratique des prélèvements multiorganes en vue de transplantations. Ils précisent les limites et le contenu de la région coeliaque et en particulier: la position du tronc coeliaque par rapport au ligament arqué médian du diaphragme, les rapports respectifs des branches collatérales de l'aorte abdominale, la place occupée par le plexus coeliaque et sa situation par rapport à la v. rénale gauche. A partir de ces éléments, ils décrivent une voie d'abord originale, transplexique, des origines du tronc coeliaque et de l'artère mésentérique supérieure. Ils montrent l'importance de cette voie d'abord, aussi bien en chirurgie vasculaire digestive que lors des prélèvements multiorganes, en vue de transplantations.
    Notes: Summary The authors report their experience based on the anatomical study of the celiac region and on the practice of abdominal multiorgan removal for transplantation. They particularly concentrate on the limits and the content of the celiac region of Luschka and particularly: the position of the celiac axis in relation to the median arcuate ligament of the diaphragm, the relations of the collateral branches of the abdominal aorta, the place being taken by the celiac plexus and its situation in relation to the left renal v. From these elements, they describe an original transplexus surgical exposure of the origins of the celiac axis and of the superior mesenteric a. They show the importance of this approach in abdominal vascular surgery and during abdominal multiorgan removal in transplantation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02346122
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  • 3
    Electronic Resource
    Electronic Resource
    Differential effects of phosphonic analogues of GABA on GABAB autoreceptors in rat neocortical slices (1998)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 357 (1998), S. 408-412 
    Details
    ISSN: 1432-1912
    Keywords: Key words Rat neocortical slices ; GABABautoreceptors ; [3H]-GABA release ; GABAB receptor antagonists ; Phosphonic analogues of GABA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of five phosphonic derivatives of GABA on the release of [3H]-GABA from rat neocortical slices, preloaded with [3H]-GABA, were investigated. Phaclofen and 4-aminobutylphosphonic acid (4-ABPA) increased the overflow of [3H] evoked by electrical stimulation (2Hz) in a concentration-dependent manner, with similar potencies (phaclofen EC50=0.3mmol/l, 4-ABPA EC50=0.4mmol/l). At 3mmol/l, phaclofen increased the release of [3H]-GABA by 82.6±8.6%, and 4-ABPA increased the release by 81.3±9.0%. 2-Amino-ethylphosphonic acid (2-AEPA) increased the overflow of [3H] by 46.8±10.9% at the highest concentration tested (3mmol/l). In contrast, the lower phosphonic homologue 3-aminopropylphosphonic acid (3-APPA), and 2-amino-2-(p-chlorophenyl)-ethylphosphonic acid (2-CPEPA), a baclofen analogue, did not modify the stimulated overflow. These results suggest that phaclofen, 4-ABPA and 2-AEPA are antagonists at GABAB autoreceptors, the latter being the weakest antagonist, whilst neither 3-APPA nor 2-CPEPA are active at these receptors. Since phaclofen, 4-ABPA and 2-CPEPA are antagonists and 3-APPA a partial agonist/antagonist on GABAB heteroreceptors, the lack of effect of 3-APPA and 2-CPEPA on [3H]-GABA release in this study suggests that GABAB autoreceptors may be pharmacologically distinct from the heteroreceptors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00005186
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  • 4
    Electronic Resource
    Electronic Resource
    Cocaine-sensitive O-methylation of noradrenaline in dental pulp of the rabbit: Comparison with the rabbit ear artery (1987)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 335 (1987), S. 32-39 
    Details
    ISSN: 1432-1912
    Keywords: Rabbit dental pulp ; Ear artery ; Noradrenaline uptake ; Metabolism ; Cocaine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Incisor pulp from the rabbit metabolises exogenous noradrenaline in concentrations between 0.12 and 1.2 μmol/l mainly to NMN. Effects of chronic sympathetic denervation indicated that in incisor pulp the NMN is extraneuronal in origin, and that DOPEG and DOMA formation, as well as a major part of the noradrenaline which accumulates in the tissue, are associated with the sympathetic nerves. NMN formation was unaffected by hydrocortisone 210 μmol/l, but was strongly inhibited by cocaine 30 μmol/l. These effects contrasted with those in the rabbit ear artery, where NMN formation was increased by cocaine 30 μmol/l and decreased by hydrocortisone 210 μmol/l. In COMT-inhibited denervated pulp, cocaine inhibited the accumulation of noradrenaline. Monoamine fluorescence histochemistry of pulp exposed to noradrenaline 50 μmol/l indicated that cocaine-sensitive uptake occurred in fibroblasts. It is concluded that O-methylation of noradrenaline in dental pulp involves prior uptake of the amine by a process resembling uptake, but which is distinguished from uptake1 by its extraneuronal location.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00165032
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    Paper (German National Licenses)
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