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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of organic chemistry 43 (1978), S. 1430-1434 
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Plant Physiology and Plant Molecular Biology 47 (1996), S. 509-540 
    ISSN: 1040-2519
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology
    Notes: Abstract Plant gene responses to changing carbohydrate status can vary markedly. Some genes are induced, some are repressed, and others are minimally affected. As in microorganisms, sugar-sensitive plant genes are part of an ancient system of cellular adjustment to critical nutrient availability. However, in multicellular plants, sugar-regulated expression also provides a mechanism for control of resource distribution among tissues and organs. Carbohydrate depletion upregulates genes for photosynthesis, remobilization, and export, while decreasing mRNAs for storage and utilization. Abundant sugar levels exert opposite effects through a combination of gene repression and induction. Long-term changes in metabolic activity, resource partitioning, and plant form result. Sensitivity of carbohydrate-responsive gene expression to environmental and developmental signals further enhances its potential to aid acclimation. The review addresses the above from molecular to whole-plant levels and considers emerging models for sensing and transducing carbohydrate signals to responsive genes.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Physiologia plantarum 35 (1975), S. 0 
    ISSN: 1399-3054
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: In a solution culture experiment with 4-week-old barley plants (variety Villa) the influence of NaCl salinization and of KCl additions on the uptake and turnover of labelled N (15NH415NO3) was studied. Labelled N was applied for 24 h at the end of the growth period.Salinization impaired growth and uptake of labelled N. The incorporation of labelled N into the protein fraction, however, was improved by NaCl salinization. Additions of KCl to the nutrient solution diminished the negative effect of NaCl salinization on growth. At both NaCl salinization levels (60 and 120 mM) K additions favoured the uptake of labelled N and particularly its incorporation into the protein fraction.It is suggested that the negative influence of the NaCl stress is not primarily due to an impaired protein synthesis, but is possibly caused by a deterimental effect of Na on other metabolic processes.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford BSL : Blackwell Science
    Alimentary pharmacology & therapeutics 11 (1997), S. 0 
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: Ranitidine hydrochloride (Zantac) is one of the most extensively studied and widely used drugs of all time. This has provided an excellent opportunity to define its safety profile. Methods: Data from 189 controlled clinical trials in which more than 26000 patients received daily doses of ranitidine for 4 weeks or more were reviewed. More than 80% of patients were treated with up to 300 mg ranitidine daily; the remaining patients received doses of up to 1200 mg daily. Eighty-seven trials were placebo controlled. Analyses of post-marketing surveillance and a database of all spontaneously reported adverse events were also evaluated. Results: Overall in the clinical trial programme adverse events were reported by 20% of those receiving ranitidine compared with 27% of those receiving placebo. The pattern of events was similar in all treatment groups with no evidence of dose-related toxicity in regimens encompassing an eightfold range of therapeutic doses. Similarly in a programme of studies designed to evaluate a dose of ranitidine of 75  mg for non-prescription (over-the-counter) use in the treatment of heartburn, ranitidine was not associated with an adverse event profile distinct from that of placebo. Analysis of spontaneously reported adverse event data allowed identification of rare idiosyncratic events. Conclusions: Review of data from a large population of controlled clinical trials with analyses of postmarketing surveillance studies and spontaneously reported adverse events confirmed the excellent safety profile of ranitidine.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 279 (1979), S. 104-105 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Two ionic fluxes, akin to those initiating and transducing nerve impulses, may be essential regulators of animal cell proliferation. This idea emerged at a recent conference* where many findings pointed to increased Na+ influx being an early, perhaps the initial, mitogenic signal, and to ...
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Cell isolation procedures and plating methods (which use arginine-free medium to select for arginine-synthesising hepatocytes6) are given in Fig. 1 (legend). About 10% of the cells in 5-7 g of normal liver are recovered for plating. Over 95 % of these cells are viable (measured by trypan-blue ...
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Colloid & polymer science 105 (1943), S. 89-97 
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Zusammenfassung Der übergang vom normal-zum supraleitenden Zustand erfolgt, zumindest dann, wenn er im Magnetfeld stattfindet, über einen Zwischen-(Mikro-)zustand, der durch 0 〈Μ 〈 1 gekennzeichnet ist (voller SupraleitzustandΜ=0). Man hat angenommen, da\ der Supraleiter in diesem Zustand aus mikroskopischen Bereichen (schmale Zylinder in Feldrichtung) bestehe, die voll sl. und durch nl. ZwischenrÄume getrennt sind. Auf Grund dieser Vorstellung lÄ\t sich zunÄchst das Verhalten sl. Hohlkörper im Magnetfeld, das auffallende Abweichungen gegenüber dem Verhalten massiver Körper aufweist, völlig verstÄndlich machen. Gewisse Hysteresiserscheinungen, die beim übergangN—S auftreten, sprechen dafür, da\ der Mikrozustand die notwendige Begleiterscheinung einer sich aus Keimen entwickelnden Umwandlung sei. Diese dynamische Auffassung der Entstehung des Zwischenzustarrdes führt zu einer ganz trivialen ErklÄrung des Mei\ner-Effektes (VerdrÄngung eines vor dem Abkühlen eingeschalteten Magnetfeldes aus dem Sl. beim übergang): in der wachsenden OberflÄche wird nach dem Durchflutungsgesetz ein Abschirmstrom induziert. Es zeigt sich schlie\lich, da\ der übergang vom normal- zum supraleitenden Zustand am ehesten zu. verstehen ist, wenn man annimmt, da\ der metallische Leiter ein Gemenge zweier Atomgattungen ist, von denen nur die eine als TrÄger des Leitungsvorganges in Betracht kommt, und da\ die UmwandlungN—S in der Bildung einer überstruktur der beiden Atomgattungen, die sich nur durch den Aufbau ihrer Elektronenhüllen unterscheiden (dia- und paramagnetisch?) bestehe. Es wird zum Schlu\ darauf hingewiesen, da\ auch bei gewöhnlichen überstrukturen (z. B. bei CuAu) metastabile MikrozustÄnde auftreten, die zu Hysteresiserscheinungen Anla\ geben.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 121 (1943), S. 488-494 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 122 (1944), S. 706-713 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Zusammenfassung Schickt man durch einen tordierten Eisen- oder Nickeldraht einen Wechselstrom beliebiger Frequenz, während der Draht gleichzeitig einem allmählich anwachsenden magnetischen Längsfeld ausgesetzt wird, so erfolgt der Anstieg der longitudinalen Magnetisierung in großen Sprüngen, die mit der Wechselfrequenz synchron sind. Der Effekt läßt sich in Analogie mit dem Sixtus-Tonks-Effekt durch die Annahme erklären, daß die zirkuläre Magnetisierung infolge der Torsionsspannung die Keime für die longitudinale Magnetisierung liefert und daß ein großer Sprung der Magnetisierung jeweils die gesamten Keime verbraucht, so daß die Sprünge in der Frequenz der keimerzeugenden zirkulären Magnetisierung erfolgen müssen.
    Type of Medium: Electronic Resource
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  • 10
    facet.materialart.
    Unknown
    Manchester : Periodicals Archive Online (PAO)
    Journal of Semitic studies. 23 (1978) 127 
    ISSN: 0022-4480
    Topics: Linguistics and Literary Studies , Ethnic Sciences
    Notes: REVIEWS
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