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  • 1995-1999  (4)
  • 1955-1959
  • 1935-1939
  • homosexuality  (2)
  • Differential gene expression  (1)
  • Gelidiales phylogeny  (1)
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  • 1
    ISSN: 1432-072X
    Keywords: Key words Slime moulds ; Physarum polycephalum ; Plasmodium development ; Differential gene expression ; Myosin ; Calcium-binding protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract During the life cycle of Physarum polycephalum, uninucleate amoebae develop into multinucleate syncytial plasmodia. These two cell types differ greatly in cellular organisation, behaviour and gene expression. Classical genetic analysis has identified the mating-type gene, matA, as the key gene controlling the initiation of plasmodium development, but nothing is known about the molecular events controlled by matA. In order to identify genes involved in regulating plasmodium formation, we constructed a subtracted cDNA library from cells undergoing development. Three genes that have their highest levels of expression during plasmodium development were identified: redA, redB (regulated in development) and mynD (myosin). Both redA and redB are single-copy genes and are not members of gene families. Although redA has no significant sequence similarities to known genes, redB has sequence similarity to invertebrate sarcoplasmic calcium-binding proteins. The mynD gene is closely related to type II myosin heavy-chain genes from many organisms and is one of a family of type II myosin genes in P. polycephalum. Our results indicate that many more red genes remain to be identified, some of which may play key roles in controlling plasmodium formation.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of applied phycology 10 (1998), S. 229-236 
    ISSN: 1573-5176
    Keywords: Gelidiales phylogeny ; gene evolution ; LSU ; rbc ; L ; SSU
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Partial sequences (1032 bp) of the nuclear-encoded large ribosomal RNA gene (LSU) were determined for 16 gelidialean species, and analyzed separately and in combination with plastid rbcL and nuclear SSU gene sequences. The number of informative characters and levels of sequence divergence among taxa are intermediate in LSU sequences as compared to that for rbcL and SSU. Analyses of the separate LSU, and a combined LSU, SSU, and rbcL data sets have identified early-diverging lineages within the Gelidiales including Gelidiella, Pterocladia, Pterocladiella, and a lineage including Gelidium and species classified in other genera. The relationships among most gelidialean taxa are well-resolved and well-supported by analyses of the combined data; however, the relationships of Ptilophora and Capreolia remain unclear. It is speculated that these two lineages have diverged from a common ancestor over an evolutionarily short period of time.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-2800
    Keywords: homosexuality ; transsexualism ; gender dysphoria ; gender identity disorder ; birth order ; sibling sex ratio
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Psychology
    Notes: Abstract Two studies were undertaken to confirm the previous findings that homosexual men in general tend to have a later than expected birth order and that extremely feminine homosexual men also tend to have a higher than expected proportion of brothers (i.e. a highersibling sex ratio). Subjects in Study 1 were Dutch, adult and adolescent, biological male patients with gender dysphoria (persistent and recurrent desires to belong to the opposite sex), who were undergoing treatment with feminizing hormones. These comprised 83 patients who reported sexual attraction to other males (the homosexual group) and 58 who reported sexual attraction to females or equal attraction to males and females (the nonhomosexual group). Subjects in Study 2 were Dutch adolescent male patients at another hospital. The homosexual group consisted of 21 gender-dysphoric homosexual teenagers referred to a gender identity clinic for children and adolescents. The control group were 21 adolescent males referred to the child psychiatry department of the same hospital for reasons other than gender identity disorder, homosexuality, or transvestism. These were individually matched to the homosexual subjects on age and sibship size. In both studies, the homosexual group had a significantly later average birth order than the comparison group. In Study 1, the homosexual group had a significantly elevated sibling sex ratio; this was not tested in Study 2 because of its small sample size. These studies add to the mounting evidence that late birth orders are common to all homosexual samples and that elevated sibling sex ratios are an additional characteristic of extremely feminine ones.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1573-2800
    Keywords: homosexuality ; memory ; masculinity-femininity ; gender nonconformity ; sexual orientation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Psychology
    Notes: Abstract Male sexual orientation is strongly associated with childhood sex-typed behavior, but there are also marked within-orientation differences. Gay men show increased variance compared to heterosexual men on retrospective measures of childhood sex-typed behavior. Individual differences among gay men for their degree of sex-typed behavior may have important implications. However, there has been little attention given to the reliability or validity of retrospective measures of such differences that are most common. Gay men and their mothers completed questionnaires assessing the men's sex-typicality during childhood. Results of structural modeling analyses found that mothers' and sons' reports were significantly associated, both regarding the general level of sex-typed behavior and the specific behaviors, supporting the validity of retrospectively measured individual differences for those characteristics.
    Type of Medium: Electronic Resource
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