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  • 1995-1999  (5)
  • 1930-1934
  • Cell culture  (2)
  • 1,2-bis-Dipyrrinon-9-yl-ethene  (1)
  • 2-butanediol)-3′-nitrotyramine  (1)
  • 53 C 25  (1)
Datenquelle
Materialart
Erscheinungszeitraum
  • 1995-1999  (5)
  • 1930-1934
Jahr
Schlagwörter
  • 1
    Digitale Medien
    Digitale Medien
    1,2-bis-Dipyrrinon-9-yl-ethene — a novelb-homo-verdian chromophore: the reaction of 9-methyl-10H-dipyrrin-1-ones with bromine (1995)
    Springer
    Monatshefte für Chemie 126 (1995), S. 983-991 
    Details
    ISSN: 1434-4475
    Schlagwort(e): 1,2-bis-Dipyrrinon-9-yl-ethene ; b-homo-Verdin ; Mesobiliverdin-XIIIα
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Die Reaktion von 9-Methyl-10H-dipyrrin-1-onen mit Brom in Dichlormethan ergab in mäßigen Ausbeuten rotgefärbte Gallenfarbstoffderivate. Sie konnten strukturell als 1,2-bis-Dipyrrinon-ethene zugeordnet werden, die ein Beispiel für die bisher unbekanntenb-Homoverdine darstellen. Darüber hinaus konnten aus der Reaktionsmischung die entsprechenden Mesobiliverdine-XIIIα isoliert werden. Die mechanistischen Aspekte dieser Reaktion werden diskutiert.
    Notizen: Summary Upon treatment of 9-methyl-10H-dipyrrin-1-ones with bromine in dichloromethane, red bile pigment derivatives were obtained in moderate yields. They were structurally assigned as 1,2-bis-dipyrrinon-9-yl-ethenes, which are examples of the hitherto unknownb-homo-verdins. In addition, the correspondingmeso-biliverdins-XIIIα could be isolated from the reaction mixture. The mechanistic aspects of the reaction are discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00811018
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  • 2
    Digitale Medien
    Digitale Medien
    The third fundamental form metric for hypersurfaces in nonflat space forms (1999)
    Springer
    Journal of geometry 65 (1999), S. 130-142 
    Details
    ISSN: 1420-8997
    Schlagwort(e): 53 B 25 ; 53 C 42 ; 53 C 25 ; third fundamental form metric ; hypersurfaces in nonflat space forms ; Einstein metric ; Codazzi tensor ; isoparametric hypersurfaces
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Mathematik
    Notizen: Abstract For hypersurfaces with regular Weingarten operator in nonflat space forms we study the relations between the intrinsic geometry of the third fundamental form metric and the extrinsic geometry of the hypersurface. We prove a theorema-egregium-type result for this metric and, in particular, give a local classification of hypersurfaces in case of an Einstein structure of this metric.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01228684
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  • 3
    Digitale Medien
    Digitale Medien
    N-Nitroso-N-M(3-keto-1,2-butanediol)-3′-nitrotyramine A new genotoxic agent derived from the reaction of tyrosine and glucose in the presence of sodium nitrite (1995)
    Springer
    Archives of toxicology 70 (1995), S. 10-15 
    Details
    ISSN: 1432-0738
    Schlagwort(e): Key words N-nitroso-N-(3-keto-1 ; 2-butanediol)-3′-nitrotyramine ; Unschedule DNA synthesis ; Genotoxicity ; Initiating agent
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract   N-Nitroso-N-(3-keto-1,2-butanediol)-3′-nitrotyramine (NO-NTA) is a product of a model browning system in the presence of sodium nitrite. In this study, the chemical structure is confirmed by spectral studies, including UV, mass spectrometry, nuclear magnetic resonance and infrared spectroscopy. NO-NTA is strongly genotoxic to the rat hepatocyte and is moderately cytotoxic to mouse C3H10T1/2 cells. Results obtained in this study indicate that NO-NTA inflicted DNA damage through the formation of a DNA adduct. In addition, C3H10T1/2 cells were treated with NO-NTA and, following addition of 12-O-tetradecanoylphorbol-13-acetate (TPA) as promotor, the increase of transformed foci indicated that NO-NTA could possibly be an inhibitor of TPA tumor promotion. A transformed cell line from NO-NTA initiated and TPA promoted foci increased saturation density and growth ability in soft agar reactive to the control line. These results suggest that the formation of a genotoxic agent of nitroso-derivatives may take place in a nitrite-containing food system during processing and cooking.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s002040050242
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  • 4
    Digitale Medien
    Digitale Medien
    Establishment of cell lines derived from oyster, Crassostrea gigas Thunberg and hard clam, Meretrix lusoria Röding (1999)
    Springer
    Methods in cell science 21 (1999), S. 183-192 
    Details
    ISSN: 1573-0603
    Schlagwort(e): Cell culture ; Clam ; Mollusc ; Oyster
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract The present study attempts to establish cell culture systems for the oyster, Crassostrea gigas Röding and the hard clam, Meretrix lusoria Thunberg. Treatment with collagenase was better than trypsin at dissociating mollusc tissue fragments for in vitro culture. Heart tissue of oyster and hard clam proved to be the most promising target tissue for the establishment of cell lines in vitro. Primary cultures of clam heart were established and successfully maintained for more than 5 months. Collagenase at a concentration of 100 μg/ml may enhance the growth of oyster and hard clam heart cell cultures in vitro.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1009829807954
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  • 5
    Digitale Medien
    Digitale Medien
    Establishment of cell culture systems from penaeid shrimp and their susceptibility to white spot disease and yellow head viruses (1999)
    Springer
    Methods in cell science 21 (1999), S. 199-206 
    Details
    ISSN: 1573-0603
    Schlagwort(e): In vitro ; Cell culture ; Prawn tissues
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract Monolayer cultures were established from ovary, heart, lymphoid tissue and peripheral hemocytes of penaeid shrimps including Penaeus monodon, P. japonicus and P. penicillatus. The most favorable conditions for the culture of penaeid shrimp cells in vitro was in CMRL and L-15 tissue culture media when used within an osmolarity range of 620--760 mmol/kg. The optimal maintenance temperature was 25 °C for tissues of P. japonicus and 28 °C for tissues of P. monodon and P. penicillatus. Among the four tissues tested, lymphoid tissue, or 'Oka organ', was superior to the other tissues for the formation of confluent cell monolayers. Cell cultures from lymphoid tissue and ovary have been subcultured up to three times. When peripheral hemocytes and heart were cultured, a maximum survival of 4 days was obtained. In contrast, cell cultures derived from ovary and lymphoid tissue were maintained alive for at least 20 days in appropriate culture systems. Neither confluent cell sheet nor adherence of cells was obtained in cultivation of hepatopancreas using the present culture systems. The results obtained from the present study also revealed that ovary extract, muscle extract and lobster hemolymph enhanced the survival of the cultured cells of penaeid shrimp in vitro. When the 'Oka organ' cell monolayer was incubated with either white spot disease virus (WSDV) or yellow head virus (YHV), no cytopathic effect (CPE) was obtained. However, at 5--7 days after establishment, significant CPE (a few foci) was observed in cell monolayers derived from WSDV- and YHV-infected Oka tissue. By electron microscopy, virions of WSDV and YHV were observed in the nuclei and cytoplasm of cultured cells. The CPE foci developed further with increased incubation time.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1009885929335
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