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  • 1
    Electronic Resource
    Electronic Resource
    Successful methotrexate therapy for adult Still's disease with Marked thrombocytopenia (1998)
    Springer
    Clinical rheumatology 17 (1998), S. 256-257 
    Details
    ISSN: 1434-9949
    Keywords: Adult Still's disease ; Methotrexate ; Prednisolone ; Thrombocytopenia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 34-year-old Japanese woman developed spiking fever, splenomegaly, arthritis, neutrophilia, hyperferritinaemia (22517 ng/ml), elevated C-reactive protein (9.1 mg/ml) and severe thrombocytopenia (1.7×104/μl). The patient had depressed antithrombin III activity and abnormally high concentrations of both fibrin degradation products and thrombin-antithrombin complexes. This condition was resistant to high-dose prednisolone therapy (120 mg/day) and non-steroidal anti-inflammatory drugs. We initiated oral methotrexate therapy (7.5 mg/week, orally) with a favourable outcome. The patient's spiking fever subsided on the first day of methotrexate administration. Elevated levels of ferritin and C-reactive protein in the sera rapidly normalised. Methotrexate rapidly improved the disease state which suggested that methotrexate act via modulation of cytokine production or secretion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01451061
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Snowballs of radioactive ions — nuclear spin polarization of core ions (1995)
    Springer
    The European physical journal 98 (1995), S. 347-351 
    Details
    ISSN: 1434-6036
    Keywords: 24.70 ; 36.40 ; 67.40
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Short-lived ions12B (beta-radioactive, T1/2=20.3 ms) sustaining nuclear spin polarization were introduced into superfluid helium at 1.7 K. It was found that the12B ions were transported as charged entities under a static electric field and that the nuclear polarization was maintained throughout the lifetime of12B nuclei. Polarization of12B was determined through beta-NMR method. “Snowball”, a singly charged microcluster of helium atoms formed around an impurity ion, is responsible for the behaviour and thus constitutes a suitable environment for preserving nuclear polarization of the core ions12B. In a separate experiment snowballs were produced by implanting8Li (T1/2=830 ms) into liquid helium and detected by means of alpha particles from the core ions to guarantee that the snowballs survive longer than the lifetime of12B.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01338403
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Two mode fission: Existence of two independent paths in the fission of actinide elements (1995)
    Springer
    The European physical journal 353 (1995), S. 35-42 
    Details
    ISSN: 1434-601X
    Keywords: 25.28.−W ; 25.28.Ge
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We attempted to confirm the existence of two-mode-fission mechanism in the232Th and238U plus4He systems. Angular distributions and differential ranges of the fission fragments were measured for both systems. Two distinct groups, symmetric and asymmetric, were observed in the anisotropy of the fragments obtained from the angular distributions in either systems. Kinetic energies of the fragments were deduced from the measured ranges and the effective distances were calculated from the data. The distribution of the resulting distances was classified into two groups also, indicating the existence of the symmetric and asymmetric modes. This strongly suggests existence of two independent paths in the fission process.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01297725
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    Paper (German National Licenses)
    Fulltext
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