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  • 1995-1999  (6)
  • dog  (3)
  • faeces  (2)
  • 3D range data  (1)
  • Brain tumour  (1)
  • Colloid body  (1)
Datenquelle
Materialart
Erscheinungszeitraum
  • 1995-1999  (6)
Jahr
Schlagwörter
  • 1
    Digitale Medien
    Digitale Medien
    The role of granzyme B-expressing CD8-positive T cells in apoptosis of keratinocytes in lichen planus (1997)
    Springer
    Archives of dermatological research 289 (1997), S. 527-532 
    Details
    ISSN: 1432-069X
    Schlagwort(e): Key words Granzyme B ; Perforin ; Apoptosis ; Lichen planus ; Colloid body ; CD8 cell
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Epidermal basal cell injury with colloid body formation is a characteristic feature of lichen planus. Infiltrated cells are thought to be responsible for the epidermal injury. Ultrastructural findings of colloid bodies are typical of apoptosis. Granzymes in cytotoxic T lymphocytes are involved in apoptosis probably together with perforin. Based on this background, we analyzed the role of granzyme B in the mechanisms of epidermal injury in lichen planus. On electron microscopy, basal and suprabasal cells showed condensed chromatin and fragmented nuclei which are typical morphological features of apoptosis. Nuclei of colloid bodies were positively stained by the in situ nick end labeling technique indicating that colloid bodies are subsequently formed in the process of apoptosis. Immunohistochemical staining showed CD8-positive infiltrating cells to contain granzyme B. Cells undergoing exocytosis also contained granzyme B. By immunoelectron microscopy, granzyme B molecules were observed to be secreted from a lymphocyte to an apoptotic keratinocyte. These findings suggest that granzyme B-positive CD8 cells seem to induce apoptosis of keratinocytes in lichen planus.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s004030050234
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  • 2
    Digitale Medien
    Digitale Medien
    Role of diffusion-weighted echo-planar MRI in distinguishing between brain abscess and tumour: a preliminary report (1999)
    Springer
    Neuroradiology 41 (1999), S. 171-174 
    Details
    ISSN: 1432-1920
    Schlagwort(e): Key words Magnetic resonance imaging ; Diffusion-weighted imaging ; Brain abscess ; Brain tumour
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Our purpose was to evaluate diffusion-weighted (DW) echo-planar MRI in differentiating between brain abscess and tumour. We examined two patients with surgically confirmed pyogenic brain abscess and 18 with metastatic brain tumours or high-grade glioma, using a 1.5 T system. The apparent diffusion coefficient (ADC) of each necrotic or solid contrast-enhancing lesion was measured with two different b values (20 and 1200 s/mm2). All capsule-stage brain abscesses (4 lesions) and zones of cerebritis (2 lesions) were identified on high-b-value DWI as markedly high-signal areas of decreased ADC (range, 0.58–0.70 [(10–3 mm2/s; mean, 0.63)]). All cystic or necrotic portions of brain tumours (14 lesions) were identified on high-b-value DWI as low-signal areas of increased ADC (range, 2.20–3.20 [(10–3 mm2/s; mean, 2.70)]). Solid, contrast-enhancing portions of brain tumours (19 lesions) were identified on high-b-value DWI as high-signal areas of sightly decreased or increased ADC (range, 0.77–1.29 [(10–3 mm2/s; mean, 0.94)]). Our preliminary results indicate that DW echo-planar MRI be used for distinguishing between brain abscess and tumour.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s002340050726
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  • 3
    Digitale Medien
    Digitale Medien
    A high-speed and continuous 3D measurement system (1995)
    Springer
    Machine vision and applications 8 (1995), S. 79-84 
    Details
    ISSN: 1432-1769
    Schlagwort(e): Slit-ray projection ; Position-sensitive device ; 3D range data ; High-speed range finders
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Informatik
    Notizen: Abstract A new system for high-speed and continuous 3D measurement is presented. It is based on the slit-ray projection method. The key component is the image plane constructed by a position-sensitive device (PSD) array that is horizontally un segmented and linear, but vertically numbered. All PSD row elements are attached to their respective analog signal processors. The analog signals are multiplexed and digitized by multiplexers and A/D converters at appropriate sampling intervals and stored in memory. By virtue of this configuration of the image plane, basis data for 3D measurement are acquired during only one scan of the slit ray at high speed in the form of memory addresses and data. Moreover, if we use large capacity and/or dual port memories, we can continuously obtain 3D range data for as many scenes as needed. The trial system has been implemented with a newly designed 128-channel PSD array and has verified our method, enabling us to obtain successive 3D range data at video rates with an error within±0.3%.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01213473
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  • 4
    Digitale Medien
    Digitale Medien
    Experimental Detection of Canine Haemoglobin (Occult Blood) in Canine Faeces by Reversed Passive Latex Agglutination (1997)
    Springer
    Veterinary research communications 21 (1997), S. 347-353 
    Details
    ISSN: 1573-7446
    Schlagwort(e): diagnosis ; dog ; faeces ; latex agglutination ; occult blood ; serology
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract A reversed passive latex agglutination test (RPLA) using anti-canine haemoglobin (Hb) antibody was developed for detecting bleeding in the lower digestive organs in dogs, and its applicability as a simple test for faecal occult blood was assessed. In Ouchterlony's gel immunodiffusion test, the anti-canine Hb antibody used to sensitize the latex reacted with canine Hb but not with Hbs, plasmas or meat extracts from pigs, goats, sheep, cattle, horses or chickens, or with fish extracts. Using latex sensitized with 50 µg/mg of anti-canine Hb IgG antibody, the lowest limit of detection for canine Hb was 21 µg/ml, and the latex reacted negatively with all test specimens other than canine Hb. In an in vitro experiment with a mixture of canine faeces and erythrocytes, the antigenicity of the Hb was found to undergo only very slight changes even when the specimens were allowed to stand for 12 h at room temperature. Hb could not be detected by RPLA in any of four successive faecal samples from three experimental dogs after infusion of autologous blood (5, 3 or 1 ml) into the stomach. In 3 other experimental dogs given an infusion of autologous blood (5, 3 or 1 ml) into the ascending colon, the presence of Hb was confirmed by RPLA in all four successive faecal samples obtained from those which received 5 or 3 ml of blood and in all except that obtained following the first defecation from the animal which had received 1 ml of blood.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1005812304532
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  • 5
    Digitale Medien
    Digitale Medien
    Immunological determination of faecal haemoglobin concentrations in dogs (1998)
    Springer
    Veterinary research communications 22 (1998), S. 193-201 
    Details
    ISSN: 1573-7446
    Schlagwort(e): diagnosis ; dog ; ELISA ; faeces ; latex agglutination ; occult blood ; serology
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Faecal haemoglobin (Hb) concentrations in apparently healthy experimental Beagle dogs and in dogs of various breeds kept in private households or at breeders were measured by reversed passive latex agglutination (RPLA) and enzyme-linked immunosorbent assay (ELISA) in an effort to define the physiological concentrations of faecal Hb in the dog. In 88% (53) of 60 experimental Beagle dogs (30 males and 30 females), the RPLA titres were 1:2 and 1:8 and the faecal Hb concentrations ranged from 40.0 to 431.5 (mean 184.1±92.6) μg/g faeces by ELISA. No significant difference was found in Hb levels or RPLA titres between males and females. Seven dogs (12%) had significantly greater RPLA titres and Hb concentrations by ELISA than the remaining dogs. In 84% (45) of the 53 dogs kept in private households or at breeders, the RPLA titres were 〉1:1 to 1:8 and the faecal Hb concentrations ranged from 7.1 to 456.7 (mean 137.5±128.7) μg/g faeces in ELISA. Eight of these dogs (15.1% of 53 dogs) had significantly greater RPLA titres and Hb concentrations by ELISA than the remaining dogs. There were no significant differences between the Beagles and dogs kept in private households or at breeders. In conclusion, in 98 (86.7% of 113) dogs the physiological concentrations of RPLA titres were 〉1:1 to 1:8 and the faecal Hb concentrations were 143.5–185.1 μg/g (95% confidence level). Approximately 13.3% of apparently healthy dogs had higher faecal Hb concentrations, suggesting the presence of subclinical haemorrhages. Four dogs suffering from colorectal cancer also had high faecal Hb concentrations.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1006025422317
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  • 6
    Digitale Medien
    Digitale Medien
    Physiological levels of C-reactive protein in normal canine sera (1998)
    Springer
    Veterinary research communications 22 (1998), S. 77-85 
    Details
    ISSN: 1573-7446
    Schlagwort(e): C-reactive protein ; circadian rhythm ; dog ; ELISA ; physiological variation ; serum
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract This study was undertaken to investigate whether the level of C-reactive protein (CRP) in the serum of dogs undergoes physiological variation, using 10 normal Beagle dogs (5 males and 5 females), 1–2 years old, maintained in a healthy condition in a controlled environment. The CRP concentration in the sera collected seven times each day at intervals of approximately 3 h ranged from 0.8 to 16.4 µg/ml (mean 5.06±3.60) in one experiment and from 0.8 to 14.0 µg/ml (mean 4.50±2.80) in a second experiment. On examining the 24-h variations in the concentration of CRP in serum, neither consistent changes nor a definite pattern of circadian rhythm was detected. During 28 days observation, only very slight changes, which seemed attributable to analytical errors, were seen in any of the dogs, except one. The concentration of CRP in the serum during the 28 days ranged from 0.8 to 22.6 µg/ml (mean 3.65±1.40). The concentrations underwent no significant variations in individual dogs, but significant differences were found between the dogs (p〈0.01).
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1006071211779
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