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  • 1995-1999  (3)
  • Arctic  (1)
  • Key words Nicotine nasal spray  (1)
  • Salbutamol  (1)
Material
Years
  • 1995-1999  (3)
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 137 (1998), S. 345-350 
    ISSN: 1432-2072
    Keywords: Key words Nicotine nasal spray ; Smoking cessation ; Nicotine replacement ; Cotinine replacement ; Expired carbon monoxide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Nicotine nasal spray (NNS) is generally considered to be an effective smoking cessation aid, but all studies to date of NNS effectiveness have also utilized group therapy sessions or frequent laboratory visits to support their subjects’ stop smoking efforts. We studied 50 volunteers before they attempted to quit smoking and again at 1, 2 and 3 months after they received NNS to assist them in quitting smoking. No other stop smoking intervention was used, which more closely mimics the common practice of many individuals trying to stop smoking with the aid of a nicotine replacement product but without other supportive interventions. We found that 50% of the subjects quit smoking for the first month, 34% were still abstinent after 2 months and 32% quit smoking for 3 months. Those who quit smoking for the entire 3 months and who continued regular NNS use throughout had 67% cotinine replacement at the end of the first month, while another group which quit smoking for only the first month with the aid of NNS had 42% cotinine replacement at the end of that month. Our data confirm that NNS is an effective smoking cessation aid, but our abstinent rate at 3 months is slightly lower than in other studies in which group therapy was provided. Our data also indicate that higher NNS-induced cotinine replacement during the first month of quitting smoking (suggesting more frequent use of NNS) is associated with longer term quit-smoking success rate.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 73 (1996), S. 364-368 
    ISSN: 1439-6327
    Keywords: Salbutamol ; Ergogenic aid ; Oxygen uptake kinetics ; Cycling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect of salbutamol (S) on cycling performance was examined in 15 highly trained non-asthmatic male cyclists. A double-blind, randomized cross-over design was used with S or placebo (P) administered using a metered-dose inhaler and a spacer device 20 min before each testing session. The S dose was 400 μg (four puffs), which is twice the normal therapeutic level. Subjects were habituated to all the laboratory procedures in the week prior to actual data collection. The subjects performed four tests under S and P conditions on separate days over 2 weeks. These included measurement of maximal O2 uptake $$(\dot VO_{2max} )$$ (cycle ergometry) with assessment of pulmonary function before and after, a submaximal (90% of ventilatory threshold) square-wave work transition from a base of unloaded cycling, a 60-s modified Wingate test, and a simulated 20 km time trial. No significant differences were observed in any of the dependent variables related to aerobic endurance or cycling performance between the S and P conditions. These results support other findings that an acute dose (400 μg) of S has no performance-enhancing properties.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of atmospheric chemistry 34 (1999), S. 365-383 
    ISSN: 1573-0662
    Keywords: stratospheric ozone ; Arctic ; chemical loss
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Geosciences
    Notes: Abstract In this paper we describe a technique for estimating chemical ozone loss in the Arctic vortex. Observed ozone and temperature profiles are combined with the model potential vorticity field to produce time series of vortex averaged ozone mixing ratios on chosen isentropic surfaces. Model-derived radiative heating rates and observed vertical gradients of ozone are then used to estimate the change in ozone that would occur due to diabatic descent. Discrepancies with the observed ozone are interpreted as being of chemical origin, assuming that there is negligible horizontal transport or mixing of air into the vortex. The technique is illustrated using ozone sonde measurements collected during the 1991/92 European Arctic Stratospheric Ozone Experiment (EASOE), meteorological analyses from the European Centre for Medium-range Weather Forecasts (ECMWF) and radiative heating rates extracted from the Global Atmospheric Modelling Programme (UGAMP) 3D General Circulation Model. Our results show that there was photochemical ozone destruction inside the Arctic vortex in early 1992 with a loss between 475 K and 550 K (around 20 km) of 0.32±0.15 ppmv in the first 20 days of January, equivalent to a rate of 0.51±0.24%/day (at the 95% confidence level).
    Type of Medium: Electronic Resource
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